Connect with us

Health

Congenital Seizures and Hemp Seed Oil

Published

on

hemp seed oil

Hemp seed oil containing CBD and THC in fixed quantities are beneficial in alleviating and even ending seizures in children. Research suggests that it is helpful for even drug-resistant epileptic attacks.

Scientists from the University of Saskatchewan performed this study. It appears in the Frontiers in Neurology. Children’s Hospital Foundation by Jim Pattinson provided financial aid for the study.

Children who have severe attacks of epilepsy do experience better life quality with a low dosage of medical hemp oil. The researchers analyzed the effects of the oil with a carefully thought ratio. It included CBD with 95 percent purity and rest of the percentage with tetra hydra cannabidiol.

They kept the bigger percentage of CBD and a smaller one of THC in the regimen

Scientists made this composition with the aid of scientific evidence. They also fixed a specific amount of the THC. The team found no intoxicating effects of the THC on using plant extracts with CBD enrichment. In the study, three out of seven children did not show any signs of seizures after using the seed oil regimen.

Most of the positive effects of using hemp seed oil were quite drastic. Some of the children were able to communicate with their families for the first time efficiently. Whereas, some children who were not able to talk or crawl were able to do so after the doses. They felt connected to their families and other loved ones.

Children with epileptic encephalopathy suffer from frequent seizures the most

Many studies have suggested cannabis items with cannabidiol to be efficient in providing aid to control epileptic seizures in children. These children include ones having epileptic encephalopathy, a congenital and severe epilepsy type.

However, most of the children do not have access to cannabis products because of a lack of knowledge. Most physicians are unaware of the required dose for the patients. Moreover, the presence of THC in the regimen makes some health care workers dubious of it.

What did the study suggest?

The study suggested that most children showed a significant alleviation in their seizures upon the daily dosage of CBD. The total dosage consisted of 5 to 6 mg of cannabis extract per kg of the weight of the child daily. Scientists also tested a dose increment to 10 to 12 mg/kg daily. They noted a dramatic alleviation in the seizures in more than half of the population under study.

The scientists realize that they have taken an important step in paving the way for a scientific answer to find treatment for epileptic seizures. There is a need to find the perfect dose and composition of the product. While administering this product, physicians will also need to monitor levels of CBD and THC in the children’s bloodstreams.

The children did not respond to multiple anti-convulsant medicines. The failure of the medication in these children motivated the scientists to find potential ways to alleviate the symptoms.

This research is a ray of hope for patients who show resistance to the drugs for epilepsy. However, there is a need for more research to apply this regimen on a vast scale.

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Cannabis

Dispensaries Funding in Missouri

Published

on

Dispensaries

Medical cannabis dispensaries had to pay $3.9 million fees to the concerning bodies of the state in Missouri. This has happened in the mid of June 2019.

Cannabis business applications are 543 in total. Moreover, St. Louis and Kansas City regions received 180 applications in total for opening cannabis dispensaries.

Moreover, Missouri will start accepting these applications from August 3. However, it has permitted groups to give associated fees of ten thousand dollars for cultivation. It has also allowed a fee of six thousand dollars to sell it. The same fees apply for cannabis derivative items.

Furthermore, the data of the applicants will be confidential according to the decision of the state. A judge last week granted a motion for the enforcement to force Missouri to release those records. However, it postponed the tentative date for the judgment summary to give time to the state for their final decision.

Missouri is the 33rd state to be legalizing cannabis for medical uses. The win constituted a percentage of 65 percent in total for Amendment 2. This led to people in business from the state to pour in huge amounts of money for the ever emerging industry.

Retailers looking forward for next year

Retailers will be introducing new lines of cannabis-infused products next year. Furthermore, the data predictions state this top up by hundred million dollars after six years.

Health care funds for incoming veterans will be requiring licensing fees and tax proceedings. Predictions suggest they will be generating around twenty million dollars annually.

People who wrote their applications have made long term planning regarding their businesses. Also, they are in anticipation of a competitive procedure for entering the legal industry.

Applications are available this summer

Application forms have been available since June 4. However, the dates for accepting business applications are from August 3 to August 17. Missouri will hopefully begin providing licenses to the businesses at the end of the year.

However, the overall proceeding will be too much costly and time taking for the applicants. It includes security and economic influence as well with the provision of business details. Sixty-nine applicants for the dispensary solely belonged to Jackson County.

The remaining applicants were twenty-one and fourteen for cannabis cultivation and infusion products, respectively.

Status of applicants in different regions of Missouri

St. Louis County had 51 people applying for dispensaries and 17 people for cultivation. The congress district in the US determines the number of dispensaries.

Missouri can approve more than 60 cultivators, 86 companies for cannabis-infused products, and 192 licenses.
Forty-eight dispensaries come this way in the St. Louis metropolitan region. Missouri counties will be getting some dispensaries for two congress districts that extend to Jefferson City.

What are some major concerns regarding cannabis business

Missouri will be licensing ten medical cannabis testing facilities. Female business owners are concerned about the state of the industry are more than half white males. It points towards unsettled discrimination in the nation.

Applicants relating to business are concerned about the insiders belonging to other states. They would be cutting the locals out from a big share of the industry.

Continue Reading

Cannabis

Can Cannabis Treat Pancreatic Cancer?

Published

on

treat pancreatic cancer

In new research, Dana Farber Cancer Institute and affiliate researchers have suggested a new way to treat pancreatic cancer. The research says that there can be a treatment for resistant pancreatic cancer with the help of a compound in marijuana. The compound is not CBD or THC. Instead, it is cannabis flavonoid.

Flavonoid is a chemical compound common in plants and fruits. It gives a vibrant color to the plant and has lots of health-related benefits.

Pancreatic cancer is a deadly form of cancer. In fact, it is the second major cause of cancer-related deaths. There are very low chances of survival. Only 20 percent of the patients survive for about a year and 8% for about 5 years. It is because pancreatic cancer cells have a greater capacity to develop resistance against treatment.

Pancreatic cancer is a very aggressive form of cancer also approaches other body parts within days. Treatment options include surgery, chemotherapy, immunotherapy, and radiation therapy. Surgery can only help at an initial stage diagnosis. Advanced stage cancer is usually defiant to these methods. There is a dire need for a treatment to improve both the quality and quantity of the patient’s life.

Investigations conducted at Dana Farber Cancer Institute

In an experiment, the researchers induced pancreatic cancer cell to rats in both vivo and vitro conditions. Later, they introduced them a cannabis flavonoid FBLO3G. It is a flavonoid extracted from Cannflavin B found in Cannabis Sativa strain. They used the method of flash chromatography to extract it from the plant.

The investigators used the modern technique of smart radiotherapy biomaterials to inject the medicine.

They published online their findings in the journal Frontiers in Oncology. Mice which were not treated died in about 20 days. About 30 to 50% of the mice exposed to radiations and FBLO3G survived for more than 40 days.

Also read- Chronic Cannabis Use and Liver Cancer

The measurements of the tumor through digital Vernier caliper, after treatment, showed a marked reduction in the size of the tumor. Cannabis flavonoid attacked both local and metastatic tumor cells. Moreover, it also reduced the number of cancer cells in other parts of the body.

What can these component do?

There is a great possibility that use of FBLO3G can increase the life of expectancy patients and may treat pancreatic cancer.

The overall discussions about the healing quality of cannabis usually revolve around CBD and THC. Both of the cannabinoids work effectively with endocannabinoid mechanism found in the body.

Although the compound FBLO3G has been extracted from the same source, it has some entirely different qualities. It is non-cannabinoid and non-psychoactive component. Unlike CBD and THC, it has nothing to do with the endocannabinoid receptor system of the body.

Cannabis flavonoid is found in very low concentration in a plant. To extract a considerable amount for experimentation is another hindrance for investigation. however, scientists are trying to synthesize it artificially in the laboratory.

The study’s authors strongly recommend the need for further research in this field. This way, their findings are applicable clinically to ease the life of patients by the end of the year 2020. It would require human involvement clinically for better verification of results.

 

 

Continue Reading

General News

CBD Association With Cannabis Dependence

Published

on

cannabis dependence

Is the cannabinoid compound agonist treatment a safe approach to reduce the use of illegal cannabis in patients? Especially if it is in combination with psychosocial aid, can it be a better choice for people who have cannabis dependence?

Using cannabinoid agonist substances is apparent to be positive addition in treating patients that are dependent on cannabis.

A study has caused a difference of opinions among some medical experts. It analyzed the treatment of cannabis addiction with nabiximol. It is a medicated spray that is derived from cannabis and contains a fixed ratio of THC and CBD. The study appears in JAMA Internal Medicine.

In the study, scientists studied the habits of 128 participants who consumed cannabis for three months. The control group had to consume the oral spray and then had to record the amount of cannabis they consumed. This study was a double-blind study in which the scientists could also not differentiate between the real and the placebo spray.

Half of the group took a placebo, and the other half took the nabiximol spray. The spray contained a dose of 80 mg of CBD and 86.4 mg of the psychoactive compound, THC.

What were the results of the study?

The studied showed an association between the use of nabiximol spray and decline in cannabis intake among cannabis dependents. People using the placebo spray had higher intakes of cannabis than the people who consumed nabiximol spray.

This concluded to the point that the pharmaceutical spray was a safe treatment for people having cannabis dependency.

Views of the medical community about the spray

Medical experts are dubious of the fact that nabiximol spray has any potential to treat cannabis dependence than any cannabis oil. The cost of the pharmaceutical spray to treat the condition is very high, and it might not even be as efficient as it seems to be. Some medical experts suggest to better rely on the natural plant or the cannabis oil instead of getting this spray.

This study holds the same phenomenon as nicotine holds when it comes to reducing smoke habit in addicted individuals. It points to the fact that it is some type of replacement therapy in which the individual is getting the same product to counteract the addiction.

Treating cannabis addiction with any type of derivative of cannabis is a safe and efficient manner to alleviate the addiction. Whether you are employing a pharmaceutical drug or a going for cannabis oil, the real solution might be cannabis itself.

What does the study demonstrate?

The study suggests that cannabinoid agonist treatment through nabiximol might be helpful. It can be especially improved in combination with many interventions of the psychosocial paradigm. It can be a safe approach to alleviate cannabis use among people who want to seek treatment for cannabis dependence.

At the current stage, there are no effective medicinal drugs for alleviating the cannabis dependence among individuals. There is a need for more extensive research to find innovative answers to tackle with the problem of cannabis addiction among people.

Continue Reading

Trending