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Chronic Cannabis Use and Liver Cancer

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Analysts from the University of Arkansas for Medical Science investigated the effects of cannabis compound, cannabidiol, on the livers of mice. According to the results, people who regularly consume the compound have greater chances of developing liver cancer.

The study appears in the Journal Molecules. It suggests that even though cannabidiol is good for relieving pain in comparison to painkillers, it is harmful to liver. Examiners at the University of Arkansas for Medical Science gave various doses of the compound to the mice under study. They gave lower doses to some mice, while they administered more doses to other mice.

Scientists used a new term for the various doses given to the mice

They gave them a technical term, ‘Mouse Equivalent Doses’ (MED) that suggested optimum dose in human maintenance in EPIDIOLEX. The dose was equal to 20 milligrams per kilogram weight.

The results were surprising. Scientists found that the mice they gave larger doses of CBD to had signs of liver toxicity within a day.

What did the results indicate?

After noting those results, they found that two-thirds of the mice in the subacute stage were either dead or were about to die within a week of the consumption. The scientists went into in-depth analysis and analyzed mice that were administered with different doses of CBD or mouse equivalent doses.

The study finds that the compound CBD in cannabis can intervene in the drug and nutrient interactive process.

CBD differentially influences around fifty genetic variants. They were in association with oxidative stress response due to more than normal free radicals. These free radicals resulted because of the response of the body. In addition to that, there was also some association found in the lipid metabolic pathway and enzymes that were involved in drug metabolism.

Previous studies do not show unanimous results about the effect of cannabis on liver

Previous researches have shown that there are certain components of cannabis that are hazardous to the liver. Out of these researches, on the contrary, one study suggested that the compound reverse the damage.

The liver damage, in that case, points to the damage done as a result of alcohol abuse, like fatty liver disease. In other cases, the compound further worsened the signs.

Moreover, hepatitis C patients who consumed cannabis showed more scars on the liver tissues than those who didn’t consume it. There was a general progression of the viral disease. Doctors are concerned that there might be certain components of cannabis that can result in liver diseases such as fatty liver diseases.

However, there is a dire need to study the effects of the compound on the liver on bigger levels, so there is no misunderstanding. At this point, it is not ideal to believe in a few types of research.

Government funding for researches is essential to provide a bigger framework and capital for more beneficial studies. However, the products for cannabis that are legal in the market do not pose such serious threats to the liver health of the consumers.

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Cannabis

United Kingdom has still a long way to go before legalizing cannabis in the country

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Though the United Kingdom is in favor of cannabis legalization, it is still illegal in the country. Let us go through the marijuana sector of the United Kingdom.

Some facts about cannabis consumption in the United Kingdom 

The people residing in the United Kingdom strongly favor the legalization of cannabis. But it is limited only to the back door market. There are more than 2.5 million cannabis users in the UK who buy it illegally as reported by the Cannabis Consultancy Prohibition Partners. It makes up almost 4% of the total population of the United Kingdom carrying a worth of more than £5 billion. 

It is important to note that 22% of the country’s population smokes tobacco, which makes up the revenue of almost £18 billion annually. Whereas, 60% population of the country drinks alcohol regularly ranging a worth of almost £68 billion. 

Legalization of cannabis in the United Kingdom

In 2018, the UK legalized the use of cannabis for medical purposes. The major reason behind its regulation was many high-profile cases of epilepsy in children came to light. Cannabis-related medications became the pain reliever for those patients suffering from such high profile epilepsy cases. Still, the use of cannabis for medical purposes is extremely less. 

Only the specialist consultant from General Hospital can prescribe it. The UK also allowed hemp oil and CBD, containing less than 0.2% THC, in the country. But a medical license is mandatory for using them too.

 Which country is the largest exporter and producer of legal marijuana across the globe?

Although the stance of the government of the United Kingdom is much strict for cannabis users, it is the largest exporter as well as the largest producer of legal medical marijuana in the world according to the reports of United Nations International Narcotics Control Board. This clearly shows that the UK exports all the legal cannabis products manufactured by the country.

There are only two products of medical marijuana in the UK that have a license. One is Sativex which is produced by GW Pharmaceuticals and the other one is Nabilone owned by Eli Lilly. 

The contradictory policy of the United Kingdom

It is evident from all the facts mentioned above that the government of the United Kingdom is still confused about whether to legalize marijuana in the country or not. While it is the largest exporter and producer of cannabis, it is very tough for patients of the country to have access to the products of medical cannabis. 

This shows the sanctimonious face of the country and it would probably cause difficulties for the cannabis industry in England including the monopoly of licensed manufacturers, high cost and barriers for the new entrants.

Some top-notch stocks of the United Kingdom

Though there are many difficulties for marijuana companies in the UK, there is a large range of public companies. According to the London Stock Exchange, most companies have other side businesses too other than cannabis. Some top cannabis stocks of the United Kingdom are GW Pharmaceuticals, Futura Medical, Integumen, AfriAg, and Sunrise Resources.

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New Jersey still waiting to Regulate Cannabis for Recreational Purposes

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The members of the Senate of New Jersey were going to vote on the bill of expungement on September 12. This bill was related to the convicts of marijuana and also involved some recommendations from Governor Philip D. Murphy.

But, as mentioned by one of the articles of NJ Advance Media, Senators including Teresa Ruiz, Sandra Cunningham and Stephen Sweeney, the President of the Senate of New Jersey, launched a new legislation. In light of the article, the new legislation will widen the restrictions on the offenders charged with cannabis-related offenses to entreat expungement.

But the bill could not pass because the Democrats failed to gather enough support in the Senate on 12th September.

History of marijuana legalization in New Jersey

In New Jersey, only medical cannabis is legal yet. Though Governor Philip D. Murphy along with other Democrats tried several times to regulate recreational cannabis, they failed to gather enough support to pass the bill.

Governor Corzine signed the Compassionate Use Medical Cannabis Act of New Jersey in 2010 to regulate marijuana for patients suffering from chronic illness. This year, Governor Philip Murphy passed the Jake Honig Law. This law relieved the restrictions including the amount of medical marijuana any patient could buy and the number of visits to physicians required to purchase it.

For recreational marijuana, Senator Scutari first launched a bill on 17th May to regulate adult-use marijuana. But the Governor of New Jersey at that time, Chris Christie, opposed this legalization. As a consequence, the bill rejected. When Murphy was elected as the Governor of New Jersey, he launched a campaign to regulate marijuana in the state. Governor Philip Murphy had full control of the Democrats in the Senate as well as in the Assembly. But he could not succeed to legalize recreational cannabis. The major reason for failure was the disharmony among the party. Also, African American members of the senate strongly opposed this bill.

The people residing in New Jersey favor the regulation of adult-use cannabis. According to the Cannabis Business Executive, a survey conducted by Monmouth University suggested that 62% of adults of the state were in favor to legalize a small amount of marijuana in possession for recreational purposes. The survey also indicated that 74% of the adults were in favor to remove the charges on offenders charged for cannabis-related offenses. In the United States of America, 33 states have legalized the use of medical cannabis. Whereas, only 11 states including Oregon, Massachusetts, Alaska, and California have allowed recreational marijuana.

Some advantages of the legalization

There are many advantages of legalizing marijuana for recreational purposes. It would not only create new job opportunities but also increase tax revenue. According to the article of NJ Advance Media, the Governor of New Jersey believes that $80 million would be collected by the state as a cannabis tax revenue in the upcoming year. It involves $20 million from cannabis for health purposes and $60 million from cannabis for recreational purposes. This regulation will also allow cannabis companies to enlarge their businesses across the state.

 

 

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This University is Launching a Cannabis Program!

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Medical cannabis has gained highlight, even in the academic ground. The University of Maryland is going to be the first US university to be offering a graduate program in medical cannabis.

The program will be offering the students an in-depth insight into the medical management of cannabis patients. Moreover, there will be an extensive study for continuing research in the field.

This will be giving a new way to transform policies regarding medical cannabis. The program will be for two years for the students of the university.

Status of cannabis in different US states

Thirty-three states in the US have legalized medical cannabis. The number will be increasing in the coming time. There will be more jobs opening up in the industry.

Since quite a while, individuals did not more often than not discuss it. In any case, presently, cannabis has compelled its way into the standard. In the United States energy toward wide based legitimization stayed at just 25% in 1995. Now, an unequaled record number of people by and by the need to see pot approved in an extensive range.

The overall expansion has been likewise as exceptional. A year back, worldwide weed arrangements hit $12.2 billion. There are in like manner over 40 countries worldwide to have waved the green flag on restorative cannabis.

A couple of things will happen before the legitimate weed industry has any shot at $166 billion in yearly arrangements. This consolidates keeping an eye on the enormous contraband market by approving cannabis in the United States and different countries.

Numerous individuals need to devour cannabis only for recreational purposes. To include further, the item can turn out to be so promptly accessible in each home in each room. Odds are it will lose its substance simply as some other conventional painkiller did. The inquiry still stays unanswered on the vulnerability of the dimension of the utilization of the item.

Be that as it may, researchers can examine thoroughly the employment of exceedingly significant dynamic elements of the substance. This way, they will be better ready to coordinate for the making of exact items explicitly intended to manage certain issues.

How will this graduate programs benefit people?

The graduates will be able to pursue a career in the medical cannabis space. Also, another fact about this program is that it will be benefiting professionals in medical and health sciences. Industry related people will be able to dive deeper into certain aspects of medical cannabis.

Many pharmacists will be able to manage better the new products coming in the market from this emerging industry. The courses will be acting as an integral tool for providing students with the knowledge they need to know about the subject.

Most of the course will be constituted of online classes. This way, more professionals who have their work shifts during the day can easily manage the course. The understanding of the course is easy even for people who do not link with medicinal studies.

The students will be able to better support not only the clinical setup but also the industries in respect to cannabis use.

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