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Cannabis May Lead to An Alteration in the Sperm’s Gene for Autism

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Autism

A recent study suggests that using cannabis may lead to an alteration in the sperm’s gene for autism. The journal Epigenetics has published this study. And it states that cannabis can bring about changes in the DLGAP2 gene in men’s sperm.

The results of the study have shown that changes in this gene take place by a process known as DNA methylation. And it has the potential to pass on to the next generation.

Using cannabis can bring changes in the methylation of DLGAP2 gene

Nowadays, many countries have legalized the use of recreational and medical cannabis. But the use of cannabis in parents may affect the nervous system of the offspring and cause conditions like autism. The fathers who use cannabis may be using them for two.

This study includes 24 men and 15 rats. And it highlights the ability of marijuana to affect the next generation. The research team has detected a significant hypomethylation at the DLGAP2 gene in the sperm of men who have used cannabis compared to the non-users.

The finding was similar in the case of mice exposed to THC (tetrahydrocannabinol). The rats born to fathers subjected to THC also had this hypomethylated state in their forebrain. These results may provide little evidence that cannabis can lead to an alteration in the sperm’s gene for autism.

Also related- These trials will help us know if Marijuana has the capacity to treat Autism

The research team has stated that these results do not define an obvious relation between the use of cannabis and autism. But still, this possible link stresses the need for further study. The team has used quantitative bisulfite pyrosequencing to validate the differential methylation in the DLGAP2 gene for the nine CpG sites in intron seven.

The DNA methylation at the DLGAP2 gene was present in the sperms of male rats exposed to THC. Moreover, the accumbens nucleus of their offspring has also shown the presence of methylation.

DNA methylation can cause a reduction in the expression of DLGAP2

In an earlier study, the research team found many changes in the gene of men’s sperm who smoked marijuana. On the contrary, this recent study has focused on specific genes, especially DLGAP2.

DLGAP2 means Discs-Large Associated Protein 2. DLGAP2 is a gene implicated in autism. And it is involved in neural signaling and the organization of synapse. Besides its link with autism, this gene is also related to PTSD and schizophrenia.

Other discoveries from this study involve a sex-based difference in the link between DNA methylation and gene activity in human brain tissues. In both sexes, there was a decrease in gene activity with an increase in DNA methylation.

But this link was strongest in females, and less maintained in males. At present, the exact reason for this difference is unknown. This variance in both sexes was significant, as the ratio of boys to girls with autism is 4:1.

The association between methylation and the expression of gene changes if the methylation change is passed along to offspring. But the fact that DLGAP2 gene in sperm is functionally important in the brain is clear, in any event. This is the first study that has shown the relation between cannabis use in men and autism in offspring.

It indicates that use the cannabis may lead to an alteration in the sperm’s gene for autism. But due to the small sample size (24 men), this study hasn’t accounted for the confounding factors. And still, these factors like sleep, diet, and physical activity may affect the study results.

 

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Cannabis

Variety Of Marijuana Strains Yield Different Health Impacts 

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Marijuana Strains

Marijuana is a plant that has many beneficial medical uses. Moreover, researchers are discovering more and more about the effectiveness of cannabis in treating various psychological and pathological conditions. The plant has been gaining popularity for its health effects. 

Marijuana is effective in reducing pain and anxiety. It is also applicable for elevating the quality of sleep, and recently it is famous for being an aphrodisiac. The impact of various strains of cannabis is different.

Marijuana strains are classified as indica, Sativa, and hybrid. However, the classification is considered controversial. Moreover, each variant-strain of cannabis generates a specific effect. But personal preferences also determine what individuals will use and how it will affect them. 

ALSO READ: Cannabis Strains Perfect For Parents During Back-To-School Season

Are There Any Marijuana Genital-specific Strains?

There is no evidence of the existence of marijuana strains that can result in genital-specific arousal. However, cannabis is usable for treating and helping to ease certain penis-specific situations. Moreover, individuals with anxiety associated with erectile dysfunction can take the anxiety-reducing strain of cannabis.

According to a 2017 study, marijuana use has a positive link with sexual frequency. Moreover, according to some studies, cannabis users have sex more often. Furthermore, there is a possibility that cannabis leads to increased libido levels. 

However, some research studies disagree with cannabis having a positive association with sex. According to a 2011 literature review, frequent marijuana use can cause erectile dysfunction. There is another study of 2010 that links daily use of weed to the inability to achieve orgasm. 

Thus, further research is essential to understand the true-effect of marijuana on sexual health. However, without sufficient evidence, people are still using cannabis to enjoy sex, boost their libido, and deal with other undesirable symptoms like pain or depression.

Various strains of cannabis generate different effects on different individuals. So far, there is no guarantee of which cannabis-strain will be beneficial for your sexual health. Moreover, it is wiser and safer to use marijuana strains with the recommendation of doctors and under their supervision. 

Strains For Arousal 

The two strains most frequently used for enhancing libido are Sativa-dominant hybrid (Sweeties) and hybrid (OG Kush). Sweeties contain 22 percent THC, while OG Kush contains 18 percent THC. 

Sweeties produce euphoria and are usually used for relieving stress, anxiety, and low libido. OG Kush has a reputation for generating happy feelings. However, the usage of OG Kush makes consumers a little sleepy. Thus, consuming it in small doses is safe and effective.

Treating Depression With Cannabis Strains

Depression can lead to multiple conditions including erectile dysfunction, lethargy, fatigue, and low sex drive. Many individuals use Strawberry Diesel and Jillybean to treat depression. Both are hybrid marijuana strains.

Jillybean and Strawberry Diesel strains contain zero CBD, but both have 16 percent THC each. Moreover, jellybean is energizing, produces euphoria, is a mood elevator, and perfect for combating depression. However, Strawberry Diesel does have a euphoric, mood uplifting effect, but it is not too energizing. Moreover, it is not sleep-inducing and thus is useable during day time.

ALSO READ: Cannabis Greenhouse Effect – Areas With More Emission

Getting Rid Of Anxiety And Stress With Aid Of Marijuana Strains

Stress and anxiety are both common libido killers. Moreover, stressed individuals are unable to enjoy and have fun. Furthermore, stress can lead individuals to exhaustion, brain fog, and irritability. It also decreases the potential for sexual pleasure. However, the use of marijuana strains will enable the consumer to reduce stress levels and soothe anxiety. 

Sherbet and Locktite are hybrid strains of marijuana containing 18 percent THC capable of producing euphoria. For arousal, individuals use Locktite, and Sherbet is effective for erogenous play. 

Moreover, if individuals desire to use more energetic strains, they can use Durban Poison and Harlequin. Both have Sativa-strain of marijuana, but Durban Poison contains 17% THC, and Harlequin contains 5% THC.

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Cannabis

Cannabis Greenhouse Effect – Areas With More Emission

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Cannabis Indoor cultivation

Cannabis can cause climate change that can affect the environment and life of human beings, reports The Conversation. The extent to which marijuana contributes to environmental alterations depends upon its cultivation technique and location.

The marijuana industry is expanding, and lawmakers are working on legalizing its cultivation, possession, and other activities across the United States. The cultivation of cannabis can occur indoor and outdoor. However, the effects of cultivating marijuana indoors are different from its cultivation in open outdoor fields.

According to a recent study, cultivating cannabis indoors results in the production of large amounts of greenhouse gasses. Moreover, the impact of these gasses depends upon the location where cannabis indoor cultivation occurs.

ALSO READ: Texas A&M Freshman Desires To Expand Cannabis Medical Use

Energy For Cannabis Indoor Cultivation

Cultivating cannabis indoors requires a controlled environment and source of energy, light, water, and other suitable conditions. A lot of electricity is utilized in producing sufficient light for the cultivation and growth of marijuana indoors. 

Moreover, cannabis cultivation at an optimal growth rate requires a lot of energy. Energy is essential for producing a comfortable growing environment for the marijuana plant. Furthermore, air conditioners and heaters are essentially required to keep the temperatures within a suitable range. 

The growth and cultivation of plants require the presence of a certain percentage of carbon dioxide. Thus, cannabis producers pump carbon dioxide into the indoor marijuana cultivating unit. However, apart from the beneficial effect in the growth of cannabis, carbon dioxide contributes to 11% to 25% of greenhouse gas emissions in facilities. 

Producers require a proper ventilation system that allows clean, fresh air at a suitable temperature and humidity levels to enter the indoor cultivating unit of cannabis. Availability of air is essential for growth but cleaning it and correcting its temperature and humidity is possible with an energy-intensive process.

Intensive energy and other production requirements increase greenhouse gas emissions. Moreover, in some regions, the emission of greenhouse gasses is higher than in other localities. 

Areas With More And Less Greenhouse Gas Emissions 

Regions with milder climates require less heating and air conditioning. Moreover, their electric grids use more clean energy. As a result, greenhouse gas emissions in such regions are less than in other areas.

According to Department of Energy, Environmental Protection Agency, and industry data, growing pot cannabis indoors results in greater emissions of greenhouse gasses in the Mountain West, Midwest, Alaska, and Hawaii in comparison with Pacific and Atlantic coasts. 

Moreover, cannabis in southern California has the lowest emissions, and eastern Oahu in Hawaii has the highest greenhouse gas emission. Greenhouse gas emissions in Southern California are at 143 pounds of carbon dioxide, equivalent per ounce of dried marijuana. However, 324 pounds of carbon dioxide equivalent per ounce emission occurs at Oahu in Hawaii. Moreover, this emission is equivalent to burning 16 gallons of gasoline

Greenhouse Emissions From Cannabis And Its Impact

The emission rate affects the environment, but authorities, cultivators, and industrialists do not consider the environmental impact. There is an urgent need to take measures regarding the greenhouse effect of cannabis cultivation to control the possibly worse situation. 

ALSO READ: Denver’s Cannabis Ordinance Will Jeopardize Hard Earned Public Health And Safety

There are old warehouses that use outdated equipment that emit more greenhouse gasses as they are less energy efficient. Furthermore, there is a need for developing new better techniques for growing high-quality cannabis with energy-efficient methods. 

Unknown variations in the cultivation process and growing methods make it hard to design effective policies that can enable producers to limit the emission of greenhouse gasses. Moreover, one serving of THC, roughly 10mg dried-flower, yields more greenhouse gasses emission than a serving of beer, wine, spirits, coffee, cigarettes.

Furthermore, it is better to cultivate and grow cannabis outdoors in open fields with a suitable environment as it will lower the emission of greenhouse gasses. 

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Texas A&M Freshman Desires To Expand Cannabis Medical Use

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Cannabis Medical use expansion

Cannabis is an illicit drug that is applicable for treating certain medical conditions. Moreover, marijuana is effective in treating psychological disorders but due to its dependency nature and ability to cause addiction, its use is restricted. 

The cannabis industry continues to explore new products, lines of administration, and much more. Furthermore, researchers are working on finding possibilities to expand the medical use of cannabis. Research and development projects continue to work and explore marijuana deeply. 

Julia Patterson is a Texas A&M freshman and has a political science major. She is the first to become one of the youngest registered lobbyists in Texas, reports The Eagle. Medical use of cannabis to treat epileptic seizures was an effective approach for Julia as she was able to recover from epileptic seizures with marijuana use.  

ALSO READ: Know Doctors Recommended Marijuana Tips

Julia Efforts For Expanding Medical Use Of Cannabis In Texas

Julia is currently working on expanding the state’s Compassionate Use Program, and for that, she seeks to influence Texas-Legislatures. She has been very active to encourage and convince lawmakers to expand their medical use of cannabis. Moreover, she has devoted herself to the cause and has been doing so since 2019.

She is also a participant in the Texas Compassionate Use Program, which allows physicians and psychiatrists to use low-THC medicines and products. Moreover, doctors under the program rules can give specific small doses for treating various health-related conditions to those patients who qualify.

In 2015 she advocated for passing the Texas Compassionate Use Program to treat more people with cannabis. In 2019 more qualifying conditions became part of the program. At the time, Julia testified before legislators. 

According to Julia Patterson, expanding the program will make a difference and improve the quality of life. Especially those that can recover from certain diseases with sufficient larger doses of marijuana. Her life altered after getting treatment with marijuana in the form of CBD-oil, and she wants to do the same for others.

Julia desires not only to expand the Compassionate Use Program but also increase the limits of THC. So far, individuals can get only 0.5% THC in any cannabis-based formulation as per the program instructions. However, the program allows for low THC % medication because it is psychoactive and capable of producing a high feeling. Moreover, according to Jayne Reuben, chronic use of high THC medications can lead to Cannabis-use disorder. 

Julia Peterson Recovers From Epileptic Seizers By Using CBD-Oil

Peterson had brain surgery and three medical implants. She was on a ketogenic diet for five years and received various medications. However, of the things she does or eats, nothing was effective in treating or controlling the seizures

She was missing a lot of normal-life and suffering due to epileptic seizures. In February 2018, she was given CBD-oil for treatment through the Compassionate Use Program. According to her, within two months, she was entirely seizure-free. She was able to have a healthy life.

ALSO READ: CBD Oil Solutions To Many Pandemic Mental Health Issues

Along with CBD-oil, she was on second-seizure medication, and the treatment made her life better for good. Moreover, her recovery via medical use of cannabis encourages and motivates her to convince lawmakers to expand the Compassionate Use Program. Furthermore, she suggests that some qualification-conditions shall be part of the list that includes allowing the use of marijuana for non-terminal cancer, PTSD, and chronic pain patients. 

According to Julia, if an individual has a chance of recovery from any disease, by using marijuana, then the doctors shall have access to give the doses. 

According to Julia, increasing the THC percentage from 0.5% to between 1% and 5% will be effective and safe. Julia elaborates that monitoring of patients who receive cannabis-medication always occurs. Furthermore, prescribers monitor, supervise, and administer medication to such patients. The prescriber keeps in check alterations in the condition to ensure intoxication does not occur. They work to improve the quality of life of the patient.

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