A recent study suggests that using cannabis may lead to an alteration in the sperm’s gene for autism. The journal Epigenetics has published this study. And it states that cannabis can bring about changes in the DLGAP2 gene in men’s sperm.
The results of the study have shown that changes in this gene take place by a process known as DNA methylation. And it has the potential to pass on to the next generation.
Using cannabis can bring changes in the methylation of DLGAP2 gene
Nowadays, many countries have legalized the use of recreational and medical cannabis. But the use of cannabis in parents may affect the nervous system of the offspring and cause conditions like autism. The fathers who use cannabis may be using them for two.
This study includes 24 men and 15 rats. And it highlights the ability of marijuana to affect the next generation. The research team has detected a significant hypomethylation at the DLGAP2 gene in the sperm of men who have used cannabis compared to the non-users.
The finding was similar in the case of mice exposed to THC (tetrahydrocannabinol). The rats born to fathers subjected to THC also had this hypomethylated state in their forebrain. These results may provide little evidence that cannabis can lead to an alteration in the sperm’s gene for autism.
The research team has stated that these results do not define an obvious relation between the use of cannabis and autism. But still, this possible link stresses the need for further study. The team has used quantitative bisulfite pyrosequencing to validate the differential methylation in the DLGAP2 gene for the nine CpG sites in intron seven.
The DNA methylation at the DLGAP2 gene was present in the sperms of male rats exposed to THC. Moreover, the accumbens nucleus of their offspring has also shown the presence of methylation.
DNA methylation can cause a reduction in the expression of DLGAP2
In an earlier study, the research team found many changes in the gene of men’s sperm who smoked marijuana. On the contrary, this recent study has focused on specific genes, especially DLGAP2.
DLGAP2 means Discs-Large Associated Protein 2. DLGAP2 is a gene implicated in autism. And it is involved in neural signaling and the organization of synapse. Besides its link with autism, this gene is also related to PTSD and schizophrenia.
Other discoveries from this study involve a sex-based difference in the link between DNA methylation and gene activity in human brain tissues. In both sexes, there was a decrease in gene activity with an increase in DNA methylation.
But this link was strongest in females, and less maintained in males. At present, the exact reason for this difference is unknown. This variance in both sexes was significant, as the ratio of boys to girls with autism is 4:1.
The association between methylation and the expression of gene changes if the methylation change is passed along to offspring. But the fact that DLGAP2 gene in sperm is functionally important in the brain is clear, in any event. This is the first study that has shown the relation between cannabis use in men and autism in offspring.
It indicates that use the cannabis may lead to an alteration in the sperm’s gene for autism. But due to the small sample size (24 men), this study hasn’t accounted for the confounding factors. And still, these factors like sleep, diet, and physical activity may affect the study results.
Diabetes Freedom Review – A Natural Way To Beat Diabetes Type 2
Diabetes is one of the most prevalent medical conditions worldwide. It is not a disease itself but untreated diabetes may lead to complications that affect the quality of life. Diabetes Freedom is a complete guide on diabetes and how to make peace with it.
Anyone who fears from diabetes needs to know the way to beat up diabetes from the root cause. Usually, it affects old age people but it is now common among people of all ages. It suggests that every person should be aware of diabetic symptoms and how to prevent and treat them naturally.
This Diabetes Freedom review will help all readers to understand diabetes well. It would further suggest practical approaches to beat diabetes at an early level. Read the complete review to know all the details.
What To Know About Diabetes Freedom?
Diabetes Freedom is a complete program designed to help diabetic people. It is a complete guide that explains the process of diabetes prevention, reserving and control. The program uses simple and powerful nutrients that work on the body to neutralize toxins and thus relieve diabetic symptoms.
Diabetes Freedom is designed by George Relly & James Freeman. James Freeman is a famous doctor from Japan who is internationally famous for his medical contributions to diabetes management. Usually, doctors recommend using medicines that help with managing the disease. But in Japan, the situation is different.
The Japanese doctors try to reach to the root cause and treat it. So that the disease never hits back again. The major causes of diabetes include toxins and fats that reduce insulin production and release. This guide will explain the best ways to get rid of toxins from the body. Following these simple hacks would make the pancreas to secrete insulin again and the body would be able to work naturally.
How Does This Program Help?
Diabetes Freedom is not any magic pill that would reverse diabetes for its users. It is a practical way to reduce the risk and save a person from developing diabetes type 2 diabetes. It works by Phyto Hack Method. This method reduces body fat and completely destroys fat deposition sites. It pushes the body to produce insulin without affecting other body functions.
The pancreas is a body organ that secretes insulin. The functioning of this organ could be affected by ceramides and fat cells. On the other side, phytonutrients are natural compounds extracted from plants that help to flush out toxins that block the pancreas. There are different types of phytonutrients that melt fat cells and de-clog the arteries. This cleaning of arteries not only reduces the risk of diabetes but also prevents other circulatory and heart diseases.
Gradually, the body is able to get self-control and the symptoms of diabetes type 2 completely vanish. Another benefit of this whole process is weight loss. The user can get rid of unwanted fat and this way he can lose weight and achieve a healthy weight.
This program doesn’t require any medicines or expensive protocols to follow. This program works by using phytonutrients, such as flavonoids, lignans, prophenylphenols, and others. These phytochemicals are highly reactive and they can affect metabolism, insulin resistance and hormonal levels of the body. With the right ingredients, it is even possible to fight against toxin damage and prevent from diabetes to go worse.
Scientific Evidence Of Diabetes Freedom
Diabetes Freedom is based on original research by the research teams of the University of Utah, Texas University, Newcastle University in England, Harvard Medical School and 14 other research studies from respectable institutes. All these researches suggest that the methods used by Diabetes Freedom can help to reverse diabetes type 2 in users.
Ingredients Suggested by Diabetes Freedom
The program focuses on the following ingredients.
- Dark Chocolate
Unlike medicines and supplements, the ingredients emphasized by Diabetes Freedom are not chemicals. These ingredients are a part of a normal diet and taste yummy. But not many people know that using these foods can reduce fat storage in the body and pump insulin production. Also, these foods are rich in phytochemicals and hence induce an effect called Potent Catalytic Effect. This way, the body is able to excrete all toxins and reverse the signs of diabetes. The program further focuses on following a healthy lifestyle with light meals and maintaining a healthy weight all for reducing factors leading to diabetes.
There are three steps that make up the Diabetes Freedom plan.
- STEP 1– “The Pancreas Restart Nutrition Plan”
- STEP 2– “The Brown Fat Boosting Blueprint”
- STEP 3– “Meal-Timing Strategies That Eradicate Diabetes Type 2”
What To Expect From Diabetes Freedom?
Expect the following outcomes from following Diabetes Freedom.
- It completely supports insulin segregation.
- It suggests the best food choices that control sugar levels naturally.
- It suggests meal times to fuel the body with food.
- It normalizes the blood glucose level and blood pressure both.
- It is 100% side effect free.
- It helps pre-diabetic patients at best.
- Using it during the early stages can prevent diabetes.
- It causes a healthy weight loss without doing any extra effort.
- It improves the quality of life.
Pros and Cons of Diabetes Freedom
- It is a natural way to fight against diabetes type 2 diseases.
- It gives detailed information on natural foods and their relation to diabetes.
- It helps to normalize the blood glucose levels.
- It shares the best tips to beat diabetes.
- It is inexpensive and affordable.
- It is easy to understand and follow.
- It has no harmful effects.
- It comes with a 100% money-back guarantee.
- It is only available online.
- After purchasing it online, the buyer is given access to download it on any electronic device.
- It has no physical status.
Ordering Diabetes Freedom Online
The price for Diabetes Freedom is only $37.00. It is only available online and all orders of Diabetes Freedom must be placed to its creator’s website. There are no handling and shipment charges for ordering Diabetes Freedom.
Every order comes with the following bonus items.
- “The Fat Burning Blueprint”
- “The Stay Young Forever Program”
- “33 Power Foods For Diabetics”
Nature has solutions for almost all health problems but not everyone can find them easily. Fortunately, it is possible to relieve diabetic symptoms and beat them in the early stages by using the right dietary and lifestyle choices. It is no less than a miracle to find a solution for diabetes that doesn’t require medicines, insulin, and expensive treatments.
Diabetes Freedom is a natural approach that improves the quality of life and helps to defeat diabetes type 2. This is a simple program but the information mentioned in it is not known to the public. So this is the right time to try a 100% side effect free diabetic solution. Do not miss this opportunity and order it before it runs out of stock.
Zenith Labs launches Fresh Flora, a new formula for Healthy Gut
Yeast infections lately have become very common. Every woman will at least be infected by it one time in their life. Zenith Labs, a renowned company for high-quality supplements has announced a new formula by the name Fresh Flora. Unlike other medications on the market, Fresh Flora is safe and only made from natural ingredients. It can help people overcome the severe symptoms of yeast infection or Candida overgrowths while keeping in check the number of healthy gut bacteria.
Fresh Flora contains doctors formulated capsules that protect the immune system and prevent further outbreaks of yeast infection in the body. Having a poor immune system, stress, constipation, bloating, feeling lethargic, and recurring yeast infection are some of the symptoms that outline Candida growth. What is more exciting? Purchasers will be given a bonus of worth $129, absolutely free.
It is important to look after the yeast infection as it prevents the fungus from spreading to other parts of the body and becoming an immune disorder. Thanks to Zenith Labs that they have created an amazing formula to fight back the Candia Overgrowth. Herbs and minerals used in Fresh Flora are clinically proven.
Directions to take Fresh Flora
To reap the best results, all the purchaser needs to do is take 2 veggie sizing capsules every day. It is not obligatory that it must be taken with a meal. To enjoy the benefits all day long, take one capsule in the morning and one in the night.
Is it safe to use Zenith Labs Fresh Flora?
Fresh Flora introduced by Zenith Labs is a result of many studies. It is specifically designed to fight back Candida and its horrifying manifestations. However, results may vary from person to person. The experience of using Fresh Flora is completely side effect free as it has only been made from natural ingredients.
These natural ingredients can easily be absorbed in the body. Each batch of Fresh Flora is checked under strict standards and is CGMP certified. However, consult a doctor before taking any supplement, especially if anyone is going under any medical treatment or having any medical condition.
Zenith Labs Fresh Flora Anti-fungal Ingredients
Fresh Flora ingredients are all-natural and side effects free. Dietary supplements have the potential to break the recurrence of yeast infections and provide a life of ease. Some of the main benefits of using Fresh Flora are highlighted below:
1) Oregano Leaf Extract
This ingredient has the ability to prevent Candida recurrence better than other prescribed medications. To put an end to Candida growth, oregano leaf extract damages the fungal membrane and prevents them from recurring.
2) Garlic Bulb Extract
Garlic bulb extract can naturally fight back against the fungal infection. It is as effective as the anti-fungal prescribed medications, but what makes it so special is its ability to give a side effect free experience and fight back resistant fungal growth.
3) Caprylic Acid
Coconut oil is a rich source of caprylic acid. While keeping a check on gut bacteria, it restricts the growth of fungal infection in the small and large intestine.
4) Pau d’Arco Bark Extract
This ingredient is extracted from the Tabebuia tree found in America (south and central region). Pau d’Arco Bark Extract penetrates the fungal membrane and then inhibits its growth.
5) Milk Thistle Seed Extract
Milk Thistle Seed Extract is an ancient ingredient that is still being used to treat yeast infections. Its effectiveness is further supported by a 2016 study in “The International Journal Of Biochemistry and Cell Biology.”
Berberine rich source is a Chinese herb, named Goldenseal. Berberine has the potential to fight back resistant Candida growth and fungal infections, which prescribed medications fail to treat.
7) Bacillus Subtilis
Bacillus Subtilis are healthy strains of bacteria that can fight back effectively against yeast infection. Other than acting as an anti-fungal ingredient, it also boosts the performance of healthy gut bacteria.
With the purchase of Fresh Flora, free video series will be given as a bonus. “Candida Overgrowth Masterclass” video series is divided into 5 parts where Dr. Ryan Shelton directs about the symptoms and precautions of getting a yeast infection. The video series has a worth of $129.
Why’s Zenith Labs Fresh Flora getting popular?
Zenith Labs Fresh Flora lately has reached many hearts due to its long list of benefits and effectiveness. Some of the main benefits are highlighted below:
- The capsules may boost the functioning of the immune system.
- It may improve digestive health conditions too, including bloating, gas, and constipation.
- The supplements naturally restrict Candida’s growth.
- The chances of recurrence of Candia growth are reduced.
- It keeps a healthy level of gut bacteria and boosts its performance.
- The capsules are easy to carry and take.
- It boosts energy levels and helps the consumer to feel free from embarrassment.
- It removes the white mucous lining on the tongue (oral thrush).
- The supplements kick off unnecessary sugar cravings.
- Consumers will be given a free bonus of worth $129.
Drawbacks of using Fresh Flora
Since Fresh Flora is only available online, it is difficult for people to buy, who do not have internet access.
How to store Fresh Flora?
Do not accept the package if the seal is broken. Try to keep it away from children and store it in a cool area at a temperature between 15 and 30 degrees Celsius.
What are the pricing details for Fresh Flora?
With the increasing demand for Fresh Flora, Zenith Labs has introduced a deal to further reduce the price. In this deal, the purchaser can get 3 bottles of Zenith Labs Fresh Flora at the price of only 1. Yes! He will be able to save $188 in one go.
On buying one bottle of Fresh Flora for $49, 2 bottles each of 60 capsules will be given free. However, this is only a one time offer. Here all the purchaser needs to do is pay the cost of one bottle with its shipping cost.
Only $19.95 is charged for shipping and handling. For international orders, the purchaser will receive his package within 1 to 2 weeks, while the USA shipping only takes 7 to 10 days. For any further queries, contact them on +1 (800) 928-1184 or email them at support@FreshFloraHome.com.
60 day 100% Money Back Guarantee (Refund Policy)
With the purchase of Zenith Labs Fresh Flora, a 100% money-back guarantee for 60 days is given. If any customer feels unsatisfied with his purchase, he can get his complete money back excluding shipping charges.
Zenith Labs has complete faith in their products, thus, they are also not asking for their empty bottles. Even if all capsules have been used by the customer, still no question would be asked. Buying Fresh Flora is a complete hassle and confusion-free experience.
Verdict – Why to choose Fresh Flora?
Fresh Flora is an all in one formula released by Zenith Labs that can help the consumer to get back into his life. It prevents the recurrence of yeast infections and digestive issues. A 60 day 100% money-back guarantee policy further solidifies its effectiveness. Along with wiping-off unnecessary sugar cravings, Fresh Flora also strengthens the immune system. Since their stock is limited, try to buy it in bulk quantity and avail the special discount, only given on its official site.
At no additional cost to you, We may earn a small commission if you decide to buy the products or services we recommended here as a part of our affiliate partnership. This only helps us maintain our website. And we only recommend quality products.
Please note that any guidelines and advice given here are not a substitute for medical advice. Please consult your physician if you are under medication or have doubts following the advice/instructions given. Individual results may vary. All images used are for illustration purposes only.
Popular Cannabis Dispensary Launches in Palm Springs
Lighthouse with its grand opening in the Palm Springs becomes the pioneer in bringing cannabis products in the Riverside County. Now residents and tourists and visitors in the area can have a nice time indulging themselves in cannabis delight.
With the upcoming 2019 holiday season and the Palm Springs Pride, the company offers a bunch of luxurious dispensaries within the mesmerizing vicinity of Palm Springs in California. The first location for this company was in the Coachella Valley.
The company Lighthouse is offering clients and medical patients with a huge variety of cannabis products in California. Not only the retail store has consumable products, you can also find cannabis accessories from there.
The organization is aimed at educating people about different uses and strains of cannabis and wants to make the cannabis for the culture approach in California knowledgeable for adult consumers.
With cooperation of many popular cannabis enthusiasts in the field, the cannabis company in the West Coast is coming with an objective to destigmatize cannabis consumption and bring out more of its positive value among people, especially medical patients who can get directly or indirectly benefitted from cannabis strains of certain types.
Lighthouse Dispensary houses certain famous and trendy cannabis products for its customers and patients such as Marley Natural, Sunday Goods, Candescent, Papa and Barkley, Care by Design, PLUS, CRU, and the list goes on.
With every new product range finding its way to the shelves of the dispensary, the variety gets even more exciting.
Ranging from edibles to topicals, flowers to anxiety relieving oils, the Lighthouse has it all. While we are talking about it, it has not forgotten your beloved pets as well.
There is something for everyone in the store – of course, those who are legally allowed to consume cannabis (no pun intended for millennials).
Till now, you can find top health and fitness cannabis products from the company as one of their specialties.
Not only you can get the products of your choice, but the carefully arranged health and wellness products serve educationally positive as well for the customers.
With more social settings like consumption lounges, outdoor patios, coffee shops, and event spaces, you can find a wide range of efforts that drive I a positive manner towards accentuating more knowledge about cannabis.
The focus is on many advantages of cannabis consumption that also includes educational classes, discussions, interactive gatherings, and much more.
Co-owner, Joseph Rubin is quite positive about the future of the next Lighthouse branch in the Palm Springs after Coachella Valley. He is “thrilled” and have further plans for “additional locations” in other popular Californian sites like Los Angeles, Massachusetts, and the Golden Gate Bridge city.
The owner is hopeful that with the spread of more knowledge through this project will open considerable number of doors in the market. Moreover, there is time to debunk all the myths relating to cannabis consumption through positive education and more engagement with the clients.
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