With the growth of the cannabis industry, there are new methods of consumption coming around. These methods have surpassed the once trendy joints and edibles. You can have a tiny film of cannabis under your tongue now. These cannabis strips are becoming quite trendy now in the emerging industry.
The characteristics that include uniqueness and efficiency are what make them stand out from the crowd.
What is the mechanism of action for these strips?
The strips interact directly with the saliva-producing membranes present in the oral cavity of a person. These membranes are resistant to wear and tear and are able to regenerate their cells at a fast pace. They have many functions. The biggest function is being a barrier and shielding the tissues of the oral cavity from microbes that might enter the oral cavity.
The mucosal membrane is also responsible for sensitization of the oral cavity which helps in eating. In addition to that, it also keeps the cavity moist to provide lubrication for easy chewing.
Why is the oral cavity absorption mechanism so highlighted?
Many scientists have used this membrane as a means to dose people with specific pharmaceutical products. It is because this membrane is highly permeable to certain molecules.
The main cause of sublingual absorption popularity among cannabis users is the efficient result that it offers to the users. Moreover, the patient will have a dose of the substance without getting any smoke. The onset is quite rapid and consistent in comparison to edibles as well.
This method of absorption skips the absorption process through the gastrointestinal system. This is a crucial step because in the GI tract the acids and enzymatic actions convert the THC into a more potent psychoactive form which can make a person get high.
This way, medical patients won’t have to get scared of the psychoactive side effects of consuming cannabis edibles through the GI route. Also, they would get twice the efficiency in half the time.
What is the right method of consuming cannabis strips?
However, you will have to keep this in mind that you need to keep the strip right under your tongue, where the sublingual gland is present. You will not get optimal results if you keep the film over your tongue.
Many cannabis users do not get the require results because they keep placing the film on their tongues. This is because many people mistake them for breath strips. Both are totally different products and have a different mechanism of action.
When you place the product under your tongue, keep your mouth closed for around five minutes. The product will get dissolved and provide with the beneficial results that you want.
The dissolving capability of these strips varies from brand to brand. Some take a minute to dissolve, while some take a few more minutes. However, experts suggest waiting for 5 minutes to get beneficial effects. If you do not wait after placing the strip and continue talking, chances are, the mechanism of action might get disturbed.
Dangerous Effects of Cannabis During Pregnancy Explained by New Research
Cannabis is a derivative of Cannabis sativa that affects the normal functioning of the brain and impairs motor coordination leading to hallucinating effect. This new study suggests that cannabis exposure has real-time devastating effects on the fetus and placental development during the gestation period in pregnancy.
The principal constituent in cannabis is Tetrahydrocannabinol (THC) and the researchers at Western University and Queens University find that regular exposure to THC has a great effect on the development of the placenta and fetus during gestation. Since recreational cannabis has been legalized in Canada, the effects of cannabis during pregnancy are beginning to be perceived.
Researchers used a rat model and human placental cells to show that regular exposure to THC during pregnancy has a great impact on not only the development of the vital organs of the fetus but also on the gene expression that is extremely important for the proper functioning of the placenta.
The researchers practically find an 8 percent deduction in birth weight and diminished growth of brain and liver by more than 20 percent during gestation in a rat model due to the regular exposure to a low-dose of THC that copies the daily use of cannabis.
An associate professor, Daniel B. Hardy at Westerns Schulich School of Medicine and Dentistry and co-author on the paper suggests that the use of cannabis during pregnancy is highly linked with low birth weight babies.
Clinical data is hard to analyze because it is perplexed by other factors. The study is a definite way that supports that THC has a direct influence on the growth of the placenta and fetus.
Oxygen and nutrients cross the placenta into the developing fetus for nourishment and the research team characterizes how THC prevents oxygen and nutrients from crossing the placenta.
A decrease in a glucose transporter called GLUT-1 is caused by the exposure to THC that was found by studying the placental cells of humans. This shows that THC is stopping the transfer of key nutrient glucose through the placenta, from mother to the fetus. A reduction in placental vasculature was also found in the rat model and infers a reduced flow of blood from the mother to the fetus.
In the researcher’s opinion the restricted growth they observed in the offspring is likely caused by both of these factors and find that there are recently no proper guidelines from Health Canada on the use of cannabis during the gestation period.
To prevent morning sickness, for anxiety, depression or social issues up to one in five women are using cannabis during pregnancy according to some studies.
A Ph.D., Associate Professor, David Natale at Queens finds in Canada and many states of the US the use of marijuana has been legalized, but its use during gestation period has not been studied well. There are very real devastating risks associated with the regular exposure of cannabis during pregnancy.
First Pneumonia Related Death Reported in China
The first case of pneumonia-related death is reported this Saturday in China. It’s a 61 years old man who died with respiratory illness. This illness was caused by a new type of virus that belongs to the same family as that of SARS. Not to forget, SARS is the same virus that took hundreds of life some years ago.
Currently, forty-one people in Wuhan are diagnosed with this new pneumonia-like disease but it is not pneumonia. The experts believe it’s a new viral strain and a statement from the central Chinese city’s health commission on its official website has confirmed it.
After this first death, seven more cases are in critical condition. But two of them are discharged after recovering from the mysterious pneumonia-like disease. The emergence of this new virus has alarmed the health officials and scared the public due to the past SARS outbreak.
In 2002-2003, or Sudden Acute Respiratory Syndrome (SARS) topped the headlines with hundreds of people dying with it in China, Hongkong and many other parts of the world. Only in China SARS killed nearly 349 people and some 299 confirmed death cases in Hong Kong. It affected the national economy of these countries at large and completely distorted the tourism industry.
Chinese scientists are investigating the root cause of this outbreak and they believe it’s a new strain from coronavirus. Coronavirus is a family of viruses that contain different mild and severe varieties of flu virus including common flu and SARS.
The researchers from Kong’s Department of Health in this death announcement on Saturday shared that genetic sequencing of this virus has been found in only one patient from the Wuhan region and is now available online. By going through its sequencing and comparing it with SARS shows that both of these viruses are 80% similar. However, it is too early to give a conclusion if it is SARS or something more deadly. They have warned the people and healthcare authorities to be vigilant this flu season.
“We will remain alert as we believe the epidemic will continue to develop,”
Hong Kong authorities are trying to follow the necessary precautions to stop the spread of this new SARS-like virus. This includes disinfectant sprays in public transport i.e. trains and airplanes, checking of passengers and awareness campaigns on the new virus.
The Wuhan health commission further shares that this first person to die from the new viral disease bought eatables from a local seafood market. This seafood market was located in the city which is currently known to be the hub of this new flu outbreak in China and was cloves on January 1st for public safety.
The patient had the chronic liver disease but he died last Thursday due to “respiratory failure”. Ever since new cases are being detected nearly every day which shows that the evidence of this disease is contagious.
World health organization (WHO) said that there are no traveling restrictions necessary specific measures to follow during trade visits to China. It also expressed full confidence in Chinese health authorities to control the viral spread as soon as possible.
Global Alliance for Cannabis Commerce announces GACC Certified™ testing
The Global Alliance for Cannabis Commerce (GACC) provides policymakers and legislators with the guidance necessary to take the nascent cannabis industry from the gray market into a global provider of medical and adult-use cannabis products.
Recently, the Company announced the launch of a nationwide, voluntary industry certification standard for safety and purity in cannabis product testing. The aim of this program is to provide licensed sellers and consumer confidence that the legal products are safe and they meet the purity standards. By the end of 2020, this program will be available to all state-licensed cannabis operations.
The Executive Director at GACC, Randal John Meyer says that with the current laws it is impossible to make sure that there are uniform standards for purity. Furthermore, GACC President Rezwan Khan added, ”GACC wants to establish a means by which consumers can have confidence in the products they buy and to provide the industry the tools to give this assurance.”
GACC and the member of the companies believe in establishing standards for safety and purity, and in creating a serious and effective testing program. Nominations for membership on the Standards Committee (terms are two years) will be open to the public beginning on Thursday, December 5, 2019, and closing on January 30, 2020.
The Board of GACC will determine the initial composition. Future members will include public nominations and will be determined by the GACCAST Standards Committee and reviewed by the GACC Board of Directors. It is expected that the GACCAST Standards Committee will take approximately nine months to establish the initial standards and protocols so that implementation can begin in 2020.
Brands such as Raw Garden, DNA Genetics, Crockett Family Farms, Urbn Leaf, La Familia, and Team Elite Genetics, and all derivative cannabis products from DNA Genetics’ and Crockett Family Farms’ genetic have pledged to support the development of the standards setting protocol and to adopt and implement it as well when it is effective.
To accommodate the entire legal cannabis industry’s access to this program, GACC will be creating a membership class, the Standard Membership, which involves minimal costs for participation, and that will provide access to the GACC Certified™ Program. GACC is also planning to arrange for testing discounts for members who use the GACC network of laboratories. The GACC President Rezwan Khan added, “Our goal is to ensure this program isn’t cost-prohibitive for any cannabis companies of any size.”
Solo sciences will be offering GACC members a substantial discount on anti-counterfeiting, instant product recall solo*CODE™ technology as they have previously partnered with GACC to ensure that medical patients and adult consumers do not unwittingly purchase counterfeit or illicit vape products.
On this account, the Executive Director of GACC added, “The combination of the voluntary GACC Certified™ consumer safety standard, particularly when combined with members’ access to substantially discounted solo*CODE™ anticounterfeiting technology, allows GACC members to provide their consumers with the confidence they need that anywhere in the United States they legally purchase a participating cannabis product, our blue leaf means it’s safe and genuine.”
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