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Cannabis, A Potential Treatment for MRSA?

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A paper was recently published by researchers at McMaster University in Canada, describing how cannabigerol potentially killed various strains of MRSA – the antibiotic-resistant staph bacteria. The team of researchers led by Eric D. Brown had taken a step further from the petri dish and started testing CBD on rodents. Their results could potentially be the first step in an attempt to make CBG the newest antibiotic in the market.

MRSA in hospitals

MRSA is an infection of the skin and soft tissues, which causes red pus-filled bumps and sores. While MRSA is not an infamous problem in hospitals worldwide, staph bacteria ( Staphylococcus aureus) is carried by one in three people in their nose. Although a common bacteria, unless it enters an open wound – which could lead to a sometimes deadly infection, it is generally harmless.

Antibiotics can successfully treat most staph infections, but antibiotic-resistant staph, known as MRSA, has proven to be dangerous. MRSA can be carried by 5 in 100 people. Although they are generally mild infections, difficulty in treatment has been shown. MRSA could potentially prove to be fatal for people with suppressed immune systems in hospitals.

Cannabis – An antibacterial agent

Cannabis has been known for its antibacterial properties. While early researchers had some ambiguity regarding the active specific compounds, recent research has been able to recognize which cannabinoids are effective against which bacteria.

When 18 cannabinoids were tested against common strains of MRSA by the McMaster University team, almost all of them had shown some efficacy against the bacteria. Most effectiveness was shown by seven cannabinoids including CBG, CBD, CBN, CBCA, Δ9-THC, and Δ8-THC. They were able to kill the bacteria at concentrations that were low enough to warrant further investigation. Moreover, CBG showed efficacy at specifically low concentrations.

CBG to kill MRSA

The biofilm that bacterial cells develop for protection makes MRSA difficult to treat. However, it appears that CBG is able to strip away MRSA’s biofilm, also leaving our blood cells’ defenses intact.

CBG helps prevent the formation of the biofilm, while also being able to strip it away. That is probably the reason that even low concentrations of CBG are effective at killing MRSA.

The question, however, is, whether CBG would do the same to blood cells. Such reactions would be a major signal to halt further research. However, researchers have reported healthy human red blood cells even after the exposure to CBG.

Treatment of MRSA in Humans

Conventionally in drug evolution, a compound is tested on animals, only after it has shown efficacy in a petri dish. The McMaster researchers treated mice with CBG and concluded that it reduced the animals’ bacterial load by half.

100mg/kg of injected CBG was proven to be the most effective dose to kill bacteria. Scaling it to human size, it would be a hefty dose. It would roughly be a quarter-ounce of puer CBG for a 154-pound human. Additionally, the general medical applications of cannabinoids have been oral, oromucosal, or intranasal, and not injected.

The Balance of Efficacy and Safety

According to researcher Eric D. Brown, despite the generally high doses of antibiotics compared to other medications, the need for safety and tolerability has to be taken under consideration when talking about the need for high doses of antibiotics to achieve efficacy. He further added how this is one of the reasons for failure in antibiotic drug discovery and development. He believes the balance between efficacy and tolerability is hard to achieve and which is why MRSA remains a problem. However, it may not be too far-fetched to envision a day when we can use CBG for the treatment of MRSA.

 

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Cannabis

Good news for Sciatica patients: CBD oil relieves the pain

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The recent studies on CBD oil have unfolded its utility in various fields of medicine. Researches on the effects of CBD oil on sciatica patients show that they can prove to be very useful in its treatment. The results have shown that the oil can work wonders to alleviate the Sciatica pain.

What is Sciatica?

Sciatica is a severe pain caused by disruption in the sciatica nerve. Anything that disturbs the nerve results in extreme and sometimes, unbearable pain.

Sciatica is a nerve that starts at the lower back and extends through the hips and legs to the toes. It sends messages from the brain to the legs via spinal cord. Since, it is a long nerve, patients usually complain of the pain at the lower back, hips, legs and heels.

Also read: Who owns the suspicious Marijuana farm near Middleton Home?

A compression on the Sciatica causes this severe pain. The major causes of compression are a herniated disk, bone spur on the spine or narrowing of the spine.

image credits: medium.com

What is CBD oil

CBD (Cannabidiol) is a chemical compound that is derived from the Marijuana plant. It relieves the pain without causing any psychoactive or mind-altering effects. CBD oil is made by extracting CBD powder from the marijuana plant. Coconut or olive oil is mixed in it for better application.

The recent researches on CBD oil have revealed its anti-seizure, neuroprotective and pain relieving properties. Due to its wondrous effects on human body, many celebrities advocate for CBD.

Utility of CBD oil for Sciatica patients

CBD oil works by increasing the number of pain modulators that stimulate a response to the pain. Our mind has cannabinoid receptors that modulate the pathways that stimulate a response to the pain and negative emotions.

As sciatica pain arises, the CBD oil applied on the respective part works to reach the brain in order to stimulate a faster response to the pain.

While the Sciatica is a very painful condition, it is mostly treatable with medicines. However, most pain relievers have side effects that cause harm in the long run. In contrast, CBD oil works naturally to enhance the receptors with minimum side effects.

Best CBD oil to relieve Sciatica

Every person’s reaction to different types of CBD oil varies from the other. One cannot say with surety, since what works for some might not work for the others. This is primarily because every person has a different set of genetics, general health and tolerance.

Natural and organic remedies take time to show their reaction. While CBD takes some time to relieve the pain, it is undoubtedly one of the harmless ways to do so.

CBD oil works best when used with the consultation of a doctor. Before buying, one should make sure that the oil contains laboratory verified ingredients.

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Trial shows a possible cure for a rare blood cancer type

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A recent clinical trial has shown positive results for a treatment plan for a rare form of lymphoma blood cancer.

What is Lymphoma?

Found in humans, Lymphoma is one of the most common types of blood cancer. Developing from a group of lymphocytes, the cancerous growth occurs around the lymph nodes, causing them to enlarge. However, a rare subtype of the cancer – Intravascular large B-cell lymphoma (IVLBCL) is sometimes hard to diagnose. Hence, leading to a relatively high mortality rate.

IVLBCL is a form of ‘extranodal malignant non-Hodgkin lymphoma (NHL)’, that causes the lymphoma cells to grow within the capillaries and small arteries or veins. Since the growth takes place inside the blood vessels, the cancer is extremely difficult to diagnose. Particularly during its early stages of developement. Further, the presentation of symptoms is generally non-specific, which makes the diagnosis even more challenging.

As of date, there is no effective treatment for IVLBCL. Since, it mostly develops in senior citizens, the patients are not able to withstand the side effects of extensive chemotherapy. Hence, majority of the patients end up denying the treatment altogether. There is an elevated risk of developing permanent “central nervous system” disorders, even after the treatment.

Also read: New Mexico – Governor in Favor of Legalization of Recreational Cannabis

Numerous studies have focused on finding a possible treatment for the disease, however, nothing significant has been developed so far.

Clinical Trial

A group of researchers from Mie University and NogoyaUniversity, Japan, recently tried to test a new treatment plan that would effectively target the cancer and also minimize the side effects. The study analyzed the patients’ data and concluded that those who underwent chemotherapy combined with “rituximab” drug, showed promising improvements in their overall condition.

However, it still does not prevent or reduce the secondary side effects on the central nervous system. According to Dr. Kazuyuki Shimada, “We considered that rituximab-containing chemotherapies combined with treatment for the secondary CNS problems could lead to further improvement in the clinical outcome.”

The trial consisted of 38 patients between the ages of 20 and 79. They were diagnosed with the Intravascular large B-cell lymphoma but were not showing signs of any central nervous system disorders. The subjects were monitored over several years and the finding were published in a scientific paper, The Lancet Oncology.

Results

The treatment procedure showed some positive results. Out of the total patients, 76% reached the two year survival goal without the progression of disease, whereas 92% reached the overall survival goal. The treatment significantly reduced the overall side effects and only 3% of the patients showed CNS damage. The team also reported that there were very few serious complications that occurred during the trial, especially in comparison to the average number of complications with a standard treatment.

Also read: Ontario Begins Virtual Inspections for Cannabis Stores During Lockdown

Dr. Shimada summarized the findings, saying, “It appears that the proposed treatment protocol might be effective in patients without apparent central nervous system involvement at the time of diagnosis.”

However, further research needs to be done to come to any definitive conclusion. Especially, since the trail group was very small, and the results might be purely coincidental. Despite that, the treatment can stills be employed in clinical practices, since it does not use any ‘novel’ drugs – i.e. all the compounds used are already being used for IVLBCL’s treatment across the globe.

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Resurge Reviews Reveal Important Information on its Benefits

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Resurge Reviews

Resurge is the latest addition in the best fat burners list of 2020, as people are purchasing Resurge more than all other popular products for weight loss. It is currently the most reviewed fitness formula on the market, revealing important details on all the promised benefits.

For almost everyone, weight loss is a ‘low-calorie diet’ and ‘two hours at the gym. But is it really that simple and anyone who does these two things loses weight? Maybe not.

More than 70% of obese people report that the conventional weight loss processes are unable to help them which is why they switch to rather controversial products with the hope of weight loss. These shady products cause more harm than benefits and leave them with nothing but side effects. Having said this, a product like Resurge seems like a light of hope for everyone who is going through the same problems.

The risk-free formula of Resurge starts working within a few days of usage. Where other products take months to show results, the users of Resurge experiences notice visible changes in their bodies within a few weeks.

Who would go for extreme body transformations or expensive products when a simple dietary supplement is doing the same? That’s why the number of Resurge users is increasing day by day along with its popularity and demand. But what makes it such an effective product? How does it help in weight loss? Here is everything on resurge that could help you to understand this product.

Why use Resurge?

What would you do if you come to know that there is one simple product that could help you to achieve your weight loss target? Would you go for it or continue doing the standard weight loss practices despite experiencing no results?

Resurge is a dietary supplement that is designed to make its user lose weight, in a natural way. Now, this ‘natural weight loss’ is often associated with a number of products but none of them explains what is it and how does it help.

A natural weight loss is when the body, on its own, loses weight. The next question that comes to everyone’s mind is that; is it possible to lose weight on your own? Of course yes, all body systems are in a perfect balance and each one of them functions to ensure this natural equilibrium. Just like breathing, thinking, blood pumping, metabolism is also a natural process through which the body sheds excessive weight and maintains a healthy weight for long.

When metabolism is affected, the natural weight balance is also disturbed which is when Resurge pills start taking their action.

It suggests that Resurge pills work on metabolism and improves it so that the body starts burning the fats all by itself. It is true not only for a total body weight loss but also for stubborn fat spot reduction like in case of belly fat, heavy thighs, or hips fat. In this way, it trims the excessive fat layers around the body, improves the health of its user, and saves him from the risk of certain obesity-related diseases such as heart diseases, diabetes, etc.

ALSO READ: Honest Success Stories of Resurge on its Official Website here

More than half of the world’s population is struggling with their weight right now and even the obesity trends in children have been increased over the last few years. It needs a complete lifestyle and dietary shift along with using a weight loss promoter product like Resurge, for maximum benefits.

Ideally, resurge pills should be used by adult and otherwise healthy individuals who are ready to start their weight loss journey. If there is a pre-existing medical condition, the best is to get its treatment first and then work on the body transformation with Resurge.

Who has created it?

Resurge has been created by John Barban, who is a famous name in the health and wellness industry. By profession, he is a fitness coach who specializes in sports nutrition and training. Resurge is a mix of his years-long experience as a weight loss coach while working with prestigious companies like BlueStar Nutraceuticals, MuscleTech, Slimquick, and others.

By academics, John is a graduate of the University of Guelph majoring in human biology and nutrition. He completed his Masters and various short courses from eminent universities such as the University of Florida. Having such a learned background, a product designed by him doesn’t leave a suspicion on the product’s quality and efficacy.

What is Resurge’s deep sleep action?

Resurge is often linked with its famous ‘deep sleep weight loss’  which sometimes confuses the new users. How is it possible to lose weight while you sleep? Common sense would probably say no, but John Barban has practically shown that it is indeed possible.

Metabolic regeneration is a restorative body function by which it repairs the damages and disturbances naturally. If necessary, it regenerates the cells and makes sure that nobody’s function is impaired or stopped.

This regeneration takes place by a special hormone, called Human Growth Hormone (HGH) which improves metabolism, prevents aging, boosts immunity, regrows body cells, increases libido, and burns fat. All these functions are managed alone by this human growth hormone which suggests its high significance in human health.

What would happen if this human growth hormone stops working? Is hormonal imbalance related to weight loss? This is true because aging is the biggest risk factor for limiting the production and release of this hormone, which is why people experience compromised immunity, libido, and limited growth in older ages. But surprisingly, aging is not the only factor in disturbing the human growth hormone levels. It is also affected by poor lifestyle and dietary habits which is why all weight loss plans emphasize healthy eating and doing exercise regularly.

In this situation, Resurge capsules make sure that the body is not going through trouble while initiating the natural recovery process. Typically, inflammation, stress, oxidative damage, limited blood supply, and other ‘minor’ problems like these affect the natural recovery. Using resurge pills daily reduces stress, improves blood circulation, boosts immunity, and regulates a healthy hormonal level, all of which aid in weight loss, indirectly.

The deep sleep weight loss by resurge is when the user is experiencing a peaceful sleep and his body is going through this restorative process while being on auto-healing mode. It also prevents sleep-related disorders i.e. insomnia and makes sure that the user wakes up fresh the next day and starts taking his daily tasks more responsibly and actively.

Meanwhile, the weight loss is initiated on its own without doing anything extra. It suggests that resurge is a multi-action formula that has remarkable health benefits in addition to weight loss alone. It works on all connecting problems with weight loss and improves them, as a result of which the body loses weight with resurge’s deep sleep action.

These methods don’t address the root cause behind the weight gain. John Barban’s Resurge weight loss supplement identifies sleep deprivation as the root cause which normally gets overlooked. He scientifically establishes the link between sleep and weight gain, showing how the Resurge weight loss supplement can solve the weight problem by restoring deep sleep.

Must Watch: A Complete Video on Clinically Proven Weight Loss Benefits of Resurge

Ingredients inside Resurge supplement

Resurge uses 100% natural ingredients inside it. The reason why is it promoted as a ‘safe’ and ‘effective’ product with weight loss benefits is because it uses only scientifically proven ingredients in its formulation. Each one of these ingredients is extracted from premium quality sources and combined as a non-GMO product, which is the perfect safe for everyone. The ingredients inside the resurge supplement are as follows.

Melatonin

It is a strong anti-oxidant that ensures good eye health, stomach health, and sleep regulation. Having it inside Resurge’s formulation is responsible for initiating the deep sleep action.

Ashwagandha

This natural ingredient has proven health benefits for stress relief and prevents anxiety-related disorders.

Hydroxytryptophan

It improves and enhances all the effects caused by melatonin for promoting weight loss by deep sleep.

L-Theanine

It improves heart health, anxiety, and stress levels.

Magnesium and Zinc

These minerals are essential to improve sleep, blood regulation, metabolism, and blood circulation.

Arginine and Lysine

These two ingredients are responsible for maintaining the human growth hormone levels inside the user’s body. It also initiates the restorative and regenerative process of the body’s natural healing.

All these up-listed ingredients are safe for human health. Their roles in sleep regulation, fat burning, and immunity boost are extraordinary which is why they are picked to be inside resurge supplement.

To manufacture this formula, John collaborated with a top-quality production unit to prepare the fully loaded resurge capsules and pack them inside a sealed bottle. This bottle comes with complete user guidelines to educate the new users on its dosage and use.

The exact information on its formula is not made public for obvious reasons. More than just a weight loss pill, resurge is popular for an all-in-one dietary formula for good health and immunity.

Benefits of using Resurge pills

As it is clear so far, Resurge is a fat burner but unlike other typical products, it has a broad spectrum of benefits to offer. Resurge user reviews suggest the following benefits of this dietary supplement.

  • Improvement in metabolism and a complete breakdown of food.
  • A control over unhealthy hunger pangs
  • Reduced food cravings especially of sweets, treats, fast food and candies
  • Improvement in sleeping time, quality and relaxation
  • High energy levels that last throughout the day
  • Better and improved immunity and low risk of weight-related diseases
  • Improvement in skin, hair and nail health
  • Complete body transformation by melting the stubborn fat layers
  • Increased libido and sexual strength
  • Improvement in eye health
  • Better focus, concentration and cognitive benefits
  • Zero side effects even when used for a long term
  • 100% natural formulation that is vegan friendly
  • Made in the latest and high-quality manufacturing unit
  • Comes with a money-back guarantee

Who should use Resurge Supplement?

Ideally, it looks like Resurge is only suitable for people who want to lose weight. But going through resurge user reviews tell that people are using it for maintaining weight as well, once they have achieved their weight loss target.

In addition to this, it is also helpful for a person who is suffering from sleep-related problems, work performance problems, and low immunity. As it is made of natural ingredients, it is safe for everyone. So even if a person has no such weight-related problem but wants to upgrade his health and immunity, resurge is a reliable product to add to the daily routine.

It is even more helpful for middle-aged people who are experiencing aging effects physically and mentally and are looking for something which is not a medicine but improves their health.

Resurge pills work even better if a user incorporates them in a healthy diet and light to a moderate exercise routine.

How to use Resurge pills?

Like other dietary supplements, resurge pills are to be taken with water. The complete dosage guidelines are mentioned on the label and every user is advised to go through them before taking the pills.

The good thing about resurge weight loss is that it doesn’t require the user to follow a crash diet or spend hours at the gym. However, switching to healthy alternatives accelerates the benefits of resurge and the user is able to get its results fast.

Resurge has helped hundreds of people to completely upgrade their lives and achieve their dream weight. However, it needs regularity of usage to show these benefits. Use it for at least four weeks to expect any results.

Side effects of Resurge

Everything inside resurge is taken from natural ingredients and natural ingredients are generally safe for human health. These ingredients are least likely to cause a side effect which means Resurge pills have zero side effects.

Still, it is necessary to consume these pills with caution. Do not overdose, mix, or combine resurge pills with other fat burners, medicines or dietary supplements to avoid interactions. If used correctly, it can not cause any side effect in its user, even after months of using it.

When would you see the results?

The online Resurge reviews tell that most of its users were able to experience its results within three to four weeks of usage. However, this is not a standard and the weight loss varies from person to person. If a user is very obese and has a sedentary lifestyle, he might take some more time to show results as compared to a person who is active and wants to lose only a few pounds.

In any case, four to eight weeks are enough for resurge pills to show their effects. This process would be slow at first but it accelerates as the user gets used to his new lifestyle and habits.  Just to add, resurge has no side effects and is 100% safe for all users.

Pros and cons of Resurge

PROS

  • Fast-acting formula
  • Natural supplement
  • Risk-free product
  • Easy to use
  • Affordable
  • No side effects

CONS

  • Suitable for adult users only
  • Not a medicine alternative

MUST READ: Resurge Updates New Discount Bundles for 2020 – Check Price Here

How expensive is the Resurge supplement?

It looks like an expensive product but it fits the budget of all users as it costs less than $100 a bottle. It is also available in bundle offers which allow the user to buy multiple resurge bottles and stock them to use later on a discounted price.

It comes with a 60-day long money-back guarantee which ensures that the customer’s money is safe. In any case, this product goes show the expected results, every user can request a refund and get his money back within 60 days of his order.

Conclusion 

Resurge is a reliable product for overall better health that comes with an ideal weight standard. It can make a person lose weight with its deep sleep action, but there are countless other benefits that make it an effective product. It is affordable and comes with a money-back guarantee suggesting it a product that any user can trust. Right now, resurge is available on discounted bundle offers. Visit its website here for a safe purchase!

 

 

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Disclaimer*

Please note that any guidelines and advice given here are not a substitute for medical advice. Please consult your physician if you are under medication or have doubts following the advice/instructions given. Individual results may vary. All images used are for illustration purposes only.

 

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