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Researchers Suggest that Standardized Dosing of Cannabis Might be Important

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With the gaining popularity of cannabis, there are guidelines that need to be followed, regarding its use. While cannabis as a medicine, require a framework for the minimization of harm, which standardized dosing may be a cornerstone of.

Currently, the varying levels of medical cannabis programs in some states and none in others, only show consistency in the therapeutic cannabis landscape Clinical research focused on the efficacy of cannabis as a treatment of specific ailments, shows that with a varying difference in the administered dosage of THC and CBD, which makes the deduction of a standard dose, quite tricky.

There is a diverse array of cannabis products and administration methods which include edibles, vapes, flower, concentrates, each with varying THC concentrations. According to a 2019 article that was published in Addiction, it was affirmed that there exists a need for standard units of THC.

Standardized dosage promotes safer use of cannabis, which has been suggested before, which included measurement of cannabis in grams and standard joints.However, neither of them could allow the varying concentrations of THC that are usually present in products such as joints, blunt etc.

In order to overcome this shortfall, the authors of the study had proposed the standard THC unit to be 5 mg, for all cannabis products and administration methods. The 5 mg dose is able to deliver meaningful effects irrespective of the administration method, and also minimizes the risk of any unpleasant or excessive effects for new consumers.

Research suggests that the labels that list the number of doses in a product, has been shown to be more understandable by consumers, rather that listing THC in milligrams alone. The development of standardized units of a dose, has been identified by the National Institute on Drug Abuse (NIDA) Cannabis Policy Workgroup, as one of its top research priorities.  Standardization of THC units could potentially offer greater clarity into the understanding of the current inconsistencies in cannabis research, along with it influence on addiction, brain development, etc.

While adverse effects after a single exposure to cannabis have been shown by some research, other studies have shown that with regular exposure, there were no differences. However, contributions to discrepancies in research can be made due to the lack of information about THC.

According to a cannabis medicine expert at Green Flower Media and Instructor of Medicine at Harvard Medical School, Dr. Jordan Tishler, an ideal unit dose for both research and clinical situations, is 5 mg. H explains how most medicines have a starting dose and, as needed, multiples of that dose are given to the patient, which is based on the research that defines that the initial unit dose is correct and can be multiplied to increase effectiveness.

While Dr Jordan Tishler affirms that according to his clinical experience, 5 mg is a very appropriate baseline, hr also explains how a fixed unit dose would not mean that it would be the only available dose for patients or that there would be any sort of restriction to that dose. Instead, it is an attempt to standardize research or clinical use to increase the predictability and reliability of results.

Standardization of THC units can also lead to the enhancement of the understanding of the effects of other cannabinoids. According to Dr. Jordan Tishler, a constant THC level could cause us to be able to discern what the effects of the medication are and what are not, along with the ultimate goal being the better understanding of cannabinoids, where they will need to be standardized as well.

According to a 2019 Addiction study, standardized CBD doses might also be recommended in future, where the health aspects of CBD are being evaluated currently with its high demand.

 

 

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Cannabis Gummies – The Best Cannabis Snack

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Cannabis gummies

Cannabis gummies are part of individuals’ life for multiple reasons, including their effect on pain relief, depression, and other conditions. Over the years, people’s consumption of weed evolves. Previously they ate weed brownies, homemade cannabis cookies, and other homemade dishes. Now people have more variety for the consumption of weed with the advent of soft drinks, candies, and other readily available foods containing marijuana. 

Gummies, mints, tarts, and candies are the new trends in the market. Moreover, gummies sales have risen remarkably in the market as they enable the consumption of weed legally. Other reasons make these little weed chewable stand out in the market.

Weed Gummies Are User Friendly 

Gummies contain cannabidiol (CBD) oil, which is one of the compounds present in cannabis or weed. It develops a positive impact on multiple mental conditions. Thus, patients with anxiety disorders, depression, and cancer-related symptoms use it as prescribed by their physician. Moreover, it has neuroprotective properties that improve the mental health condition of individuals.

ALSO READ: Cannabis Industry- A Way to Business or Social Justice in Society

Eating CBD in the form of gummies is easy for administration, and individuals can consume it on their own. CBD-gummies are quickly chewable, and individuals can accurately take a specific dose at each administration. 

Eating weed-chocolate and other foods incorporated with cannabis provide the drug, but its dose varies. On the other hand, gummies will provide the same dosage at each self-administration. 

Cannabis Gummies Any Time

The thing with various dishes is that you cannot consume the same meal for days and need alteration to taste something new. You can eat brownies or cookies once a week or every other day. But consuming them daily is not easy as you will lose appetite for the same dish. 

However, CBD-gummies have no such problem as individuals can eat them anywhere, whenever they want. Moreover, there is always room for gummies, unlike occasional eats like mints and tarts. 

The calorie intake is also lower in gummies consumption than other desserts like brownies, cookies, etc. Chef Matt Kulczycki is the edible product manager for CannaCraft, California. According to Chef Matt Kulczycki, gummy provides an easy way to eat cannabis. Also, a quick way to snack on something.

Longer Shelf-Life Of The Cannabis Snack

Usually, baked foods get old with time and are no longer fresh for consumption. But gummies and candies comparably have a longer shelf life, and they remain free of contamination for a longer duration if it is within its wrapping. 

Moreover, risks of melting, deforming, and flavor alterations are lower with weed-gummies than other snacks like chocolates, brownies. Also, gummies do not require any specific storage condition and remain in form for a longer duration wherever you take them. 

ALSO READ: How to Make Ice Cream Infused with Cannabis

Evolving Is Part Of Life

Evolution occurs naturally over the years and brings changes in nature. Similarly, with time science makes progress and formulates more advanced technologies. Like that, food items and their formulation also change with time. 

Moreover, the type changes depending upon the manufacturing procedure, and the state of cannabis used for forming the Gummies. Gummy may contain any one of the following: pectin, gelatin, distillate, live resin, for manufacturing a different type. Some of them also contain additives like melatonin and terpenes. 

Manufacturers alter production methods and product formulas to formulate weed gummies of great taste, efficacy, and reasonable cost. According to Chef Kulczycki, the cost of adding CBN and CBG is so high that its difficult to add them to the product. Sleep-gummy and fruit chews, similar to Starburst and Mamba, are ready for launch in the market. Sleep gummy contains 5mg of THC and other compounds of medicinal importance. 

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Weed Illegal Possessors Fined By Police

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Weed Illegal Possessors Fined By Police

As health care professionals condemn the use of weed illegally, the situation has become more critical during the coronavirus pandemic.

Illegal Activities Late At Night In Hampshire  

According to the Island Echo, three friends from different backgrounds were busted by police for not following lockdown-instructions at night on 22nd January.

Police stopped a trio of friends in Hampshire. The police discovered that not only they are breaching COVID-19 lockdown. But they have a large amount of a controlled drug. The three men did have a wish-list purchase, but the Hampshire Constabulary officer was not convinced with it.

Having weed illegally in one’s possession is against health laws. As a result of breaching COVID-19 lockdown and health regulations, each of the three was fined £200 ($348).

Maggie Blyth is the assistant chief constable of Hampshire. According to Blyth, authorities reintroduce the national restrictions. Further, she added that there is a need to take immediate action against breaching the law. Multiple groups and individuals have gone against the instructions of authorities for controlling coronavirus pandemic.

ALSO READ: Does Cannabis Affect Your Brain?

Government Policies For Coronavirus Lockdown

The government makes videos for public awareness and recommends them to stay within their homes or apartments. Moreover, because one of every three individuals is asymptomatic. Such individuals are carriers of coronavirus and have no symptoms of infection.

Authorities have given clear instructions recommending people avoid public gatherings and unreasonably leave during the lockdown.

Coronavirus is spreading exponentially. The U.K. government recommends individuals stay at home unless it is an emergency or an urgent matter. However, there are few other situations in which outdoor visits are permissible.

People can purchase necessities for life or do work relating to services that cannot be done from home. Furthermore, exercising within home premises with a trainer is permissible if there is a distance of two meters between individuals.

However, purchasing class B drugs that are controlled drugs is not legal according to law. Moreover, having an immense amount of weed or cannabis without prescription is illegal and can result in five years imprisonment, a fine, or both.

ALSO READ: Cannabis Industry- A Way to Business or Social Justice in Society

Legal Professionals Remarks On Weed (Cannabis) 

According to Sara Zborovski, it is not permissible to promote weed or cannabis under section 16, even for educational purposes. There are certain boundaries within which information about weed can be provided for medical purposes. The age of people who are getting educational information about cannabis also matters. However, any information regarding cannabis for promoting its sale in public is not permissible.

According to Matt Maurer, education about cannabis is continuing under strict rules without any promotional campaigns encouraging its sale. According to Paul Lewin, the law permits discussion and teaching of the medical benefits of cannabis within limitations.

However, cannabis health benefits are remarkable in improving the condition of patients with epilepsy. But illegal purchase and possession of drugs are punishable under the law. Moreover, individuals can face years of imprisonment for illegal-activities regarding drug sale and purchase.

Sometimes individuals with illegal drug activities have to pay heavy-fines. Moreover, it depends upon the number of controlled drugs like cannabis found at the crime scene. There is a possibility of receiving imprisonment and a fine by the culprits from the court.

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Does Cannabis Affect Your Brain?

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Does marijuana affects your brain?

Cannabis has a lot of effects on human body-positive and negative too. Science is focusing on the unrevealed face of marijuana. There are immense benefits of medical marijuana use but recreational use can ultimately lead to addiction and then the adverse effects can come into notice. According to the pieces of evidence, it seems that cannabis may have benign effects on the structure of the brain and not producing lethal damage. Cannabis abuse is a very common problem worldwide. With the on-going pandemic situation, the usage of cannabis has increased. More dispensaries are opening up and the stock is also rising. These days cannabis is the most common drug of abuse.

Cannabis and schizophrenia

The relationship of cannabis with schizophrenia and the effects of smoking marijuana are evident. The changes in the brain could lead to psychosis. According to recent findings the heavy use of cannabis results in some adverse consequences like the occurrence of acute psychotic episodes and the development of severe schizophrenia in people. After terminating the use of cannabis episodes of schizophrenia are seen. The recent studies have proven to show a controversy about heavy usage of cannabis whether it can cause irreversible brain damage. In addition to this, a controversy has arisen about the use of cannabis resulting in a chronic psychosis due to the alteration in the brain caused by cannabis.

Experimentation on Rats

An experiment was performed on rats which provided enough evidence that exposure to marijuana can result in long-term or permanent adverse alteration in the brain. During the experiment, the rats were exposed to THC before their birth. Soon after birth or during adolescence different problems and notable issues with specific learning and memory tasks came into evidence. Exposure to THC is interlinking with the structural and functional change changes in the hippocampus.

ALSO READ: 5 Surprising Health Benefits of Using CBD Gummies

Effect of marijuana on the brain

If you imagine the impact of marijuana on brain structure in humans so it shows conflicting analysis. Few studies suggest that using marijuana daily can alter connectivity and reduce the volume of specific regions of the brain. These regions of brain are involved in functions like memory, learning, and impulse control. Other studies suggest that there are no significant structural differences in the brains of people who don’t use drugs. The use of marijuana resulting in the impairment and alteration of the drugs is highly dependent on the age when a person began using marijuana.

In addition to this the age and the time duration for which the person has been using also matters. Some studies also suggest the decline in IQ is link with the use of marijuana especially when they start using it in adolescence. On the contrary, not all studies show the same evidence. Few studies suggest that using cannabis does not affect IQ level. Along with using cannabis multiple factors come into play in lowering the IQ level like genetics, age of use, frequency of use, duration of use, and environment.

ALSO READ: Possibility of Brain Disorders in COVID-19 Patients

THC, a Major Component of Weed

The major psychoactive ingredient, THC stimulates the part of your brain that responds to pleasure, food, and sex. This triggers the chemical, dopamine which leads you towards a euphoric and relaxed feeling. Vaping, smoking, drinking, and eating weed may leave you in different states. It may leave you afraid, anxious, and panicked. Also if you have any mental health conditions it might worsen. It can also drive you towards the use of clinical depression.

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