A recent Israeli study has found a possible treatment for COVID-19 complications in cannabis. The chemical CBD (cannabidiol) has been studied in a combination with a cannabis terpene (NT-VRL). This CBD is one of the key ingredients in cannabis Sativa. Meanwhile, the cannabis terpene NT-VRL (patent of Ebyna) is an aromatic chemical from the flowers of the plant. When administered in combination, there has been a noticeable positive effect on ‘cytokine storm’, a feared complication of COVID-19.
Cytokine storm is a dangerous reaction to COVID-19 by the body’s immune system
The term ‘cytokine storm’ refers to a chain reaction of immune cells, causing increasing levels of inflammation. Because the body is responding to the coronavirus infecting the patient, it secretes small proteins called ‘cytokines’. Usually, these have small but important roles in helping kill off the virus by creating inflammation and fever. However, when this reaction goes unchecked, it can be deadly if untreated. The patient would undergo very high levels of fever, fatigue, inflammation, and in worst-cases, respiratory failure.
This is why the recent discovery that COVID-19 can lead to cytokine storm was so shocking. It meant that even young, healthy people with strong immune systems would be susceptible to potential deaths from this disease. Furthermore, the most widely-used drug of choice for treating this, dexamethasone, is undergoing a global shortage.
The company, Ebyna, had patented the cannabis terpene, NT-VRL
The study was a collaboration between Ebyna, the terpene company, and Cannasoul, a cannabis research entity. Thus, Ebyna and Cannasoul’s joint venture led to the formation of an inhalant drug. This contained NT-VRL, to be administered with or without CBD. The aim of the study was to investigate the effects they had on treating cytokine storm from COVID-19.
Long just dismissed as simply useful in the flavor/smell of cannabis products, terpenes were shown to be very effective in this case. When combined with the CBD, which has also been shown to have positive health effects, it was remarkable. The combined therapy of both CBD and NT-VRL significantly improved symptoms of cytokine storm from COVID-19.
“This type of delivery [inhaled, rather than ingested] method is a game-changer enabling us to achieve therapeutic qualities from these unique phytochemicals like never before,” said Nadav Eya, the CEO of Ebyna. He was referring to the unexpected efficacy of the NT-VRL therapy in this COVID-19 complication.
Other studies confirm Ebyna-Cannasoul’s findings
Outside of Israel, several studies report similar findings. More and more researchers are turning to cannabis byproducts to battle the COVID-19 pandemic.
Igor and Olga Kovalchuck, researchers from Canada, were both developing a new strain of cannabis. Their aim was to extract anti-cancer drugs from it. However, the new COVID-19 pandemic caused them to shift focus towards combating the coronavirus. Their strain is hoped to be able to produce a drug that could reduce the communicability of SARS-CoV2. It would do so by restricting the ACE-2 receptors in the body.
All in all, Ebyna and Cannasoul’s NT-VRL terpene may just be revolutionary. The existence of terpene as an anti-cytokine storm drug is still debatable, and more research is still required. However, their study and that of corroborators have shown that cannabis is even more useful a plant than we had ever suspected. For more news and updates on the state of the CBD-terpene therapy, stay tuned. In the meanwhile, check out other recent studies on CBD here.
Cannabis & Sleep – 5 Factors To Contemplate
Something one should be aware of is the various effects of the different types of cannabis on the user. While marijuana is considered an excellent tool to achieve peaceful sleep, there are a few tips that are necessary to follow. Hence, it is advisable for individuals hoping to try this for the first time, to gather enough information from any friends that may have used marijuana to sleep, or found immense relaxation from the herb which can promote better sleep.
Researchers have studied the plant and its benefits and harmful effects on the users for years now. They gathered anecdotal evidence from individuals with different levels of insomnia to test the effectiveness of cannabis. The anecdotal evidence suggested that the use of cannabis promoted relaxation which in turn led to hours of uninterrupted sleep.
While marijuana can have quite the sleep-inducing effects, it is essential to study the association of sleep with cannabis. Here are 5 factors that any individual needs to take care of when using marijuana to promote better sleep.
Dosage of cannabis
This goes without saying, but dosage plays a critical role in the effects of cannabis or any drug that the user can achieve. Varying dosages can significantly affect the way cannabis interacts with the individual. With different experiences with the plant, it is essential to proceed carefully. Smoking too little may not give rise to any helpful effects for the user.
Meanwhile, smoking too much may lead to weed-induced paranoia and cause enough anxiety to keep the user awake instead. Hence, when using marijuana for sleep, one should attempt to promote a relaxing and peaceful environment around themselves. It is also advisable to exclude any forms of overstimulation with the inclusion of too much alcohol or screentime.
Gradually increase your marijuana intake and take the signals from your body, into notice to determine how much dosage is just the right amount for your uninterrupted rest.
Consumption methods are also significant in the way cannabis may affect the user. With a variety of consumption methods available, the user has can suit whatever suits them. However, this will significantly affect the intensity and speed of the reaction.
Edibles may take a few hours to allow your body to experience the desired effects. On the other hand, vaping or smoking can be quicker options. However, while the latter may be quick, it comes with the danger of inhalation of smoke which can be an active issue for many individuals, especially during the pandemic.
Consequently, it seems reasonable to analyze the different consumption methods to determine whatever method suits you best, and plan accordingly.
Types of Cannabis
From sativas to indicas, and THC-based to CBD-based, he different types of cannabis produce different effects. While Indica strains promote relaxation giving rise to sleepy effects, sativas or a hybrid could work well with many individuals as well.
It is important to acknowledge the variety of cannabis and how this will be a trial-and-error process to determine the perfect strain for specific individuals. Hence, don’t hesitate to experiment with different types of cannabis, while keeping track of the effectiveness of each.
If you haven’t actively consumed marijuana during the night, the groggy feeling may add to your experience which can be confusing. While weed hangovers aren’t really strong and common as others, their existence is undeniable.
While there hasn’t been enough research, low-quality marijuana is seen to have popularly given rise to these hangovers. Drinking lots of water, with a healthier diet for the day, may help cope up with the hangover. Additionally, make sure to track your cannabis intake during the course of the day.
Modifications in dreams and sleep patterns
One of the significant effects of cannabis on sleep is the lack or absence of dreams, which is caused owing to the limitations in REM sleep. This is the deepest stage of sleep in which dreams usually occur. However, research shows that REM sleep is essential for optimal learning and rest.
While the relationship between sleep and cannabis is not fully understood, taking necessary measures can prove to be helpful and efficient. These measures include monitoring of cannabis usage, sleep patterns. However, this is especially if the sleep may not seem as restful as it should be.
CBD Is Effective for Treating Psoriasis and Acne – Myth or Not?
Many countries use cannabidiol or CBD for its therapeutic properties. It is one of those 113 cannabinoids in Cannabis Sativa, which is scientifically-proven for its benefits. Apart from providing relief for stress, anxiety, epilepsy, and arthritis, it is widely used in the skincare industry. There are many skincare brands, which are using CBD as a major ingredient in their products to target skin issues like acne and psoriasis.
The skincare industry has reached new heights of success after CBD products started taking their own place on skincare shelves. CBD oil enriches the skin with omega-3 and omega-9 fatty acids. It helps many people to keep their skin supple, fresh, and moisturized. Their benefits do not restrict over here; they are even useful for healing skin and treating psoriasis, acne, and eczema.
Should You Use CBD Oil Products for Acne?
Even though the market has hundreds of acne treating products, not all of them are effective and useful. Some are even meant to trigger more inflammation. A best acne-treating product has the property to kill the bacteria and reduce the oil production that clogs pores.
A 2014 study found that CBD has the potency to regulate sebum production. When excess sebum is mixed with dead cells and pollutants, it clogs the pores and produces acne. Also, it prevents the triggering of the inflammatory cytokines. The activated cytokines result in acne.
CBD shows strong antifungal and antibacterial effects to prevent skin infections, which later results in acne due to pollutants and dirt in the surroundings. Many CBD products, with their anti-inflammatory and anti-bacterial properties, follow the rules of best acne products strictly. They are not only best for facial acne but body acne too.
Can CBD Treat Psoriasis?
Psoriasis, an autoimmune skin disease, causes rapid mitosis of skin cells. This quick division results in the accumulation of the immature and dead skin cells underneath the surface of the skin. It causes red scaly patches on the skin that are not contagious.
There are a number of studies that support CBD as a potential treatment for psoriasis because of its powerful therapeutic properties. Our endocannabinoid system comprises of CB1 and CB2 cannabinoid receptors. Cannabinoid works on them to regulate and boost the immune system. It suppresses excessive epidermal growth and accumulation.
It is blessed with strong anti-inflammatory properties and rich content of omega-3 and omega-6 fatty acids to moisturize and hydrate the skin. A 2007 study further provides evidence of CBD as an effective treatment for psoriasis.
Ways to Incorporate CBD in your Daily Routine
The most common and effective way to benefit from CBD for psoriasis and acne is to use it in topical form. Apply any CBD ointment, lotion, or cream to the required area until it gets completely absorbed. So far, none of the users have reported side effects.
With topical use, there is also a need to incorporate cannabinoid tinctures and capsules for psoriasis treatment. For effective treatment of psoriasis, there is a need for both external and internal intervention.
Since the new laws of CBD legalization in the United States, online stores have been gaining popularity. You can also get your CBD skincare products from any licensed dispensary. A number of CBD skincare products are available on the market, ranging from small capsules to serums.
CBD is effective for the treatment of both acne and psoriasis. However, it is better to consult a dermatologist first to adjust your safe consumption and set the instructions. Alternatively, you can start with a small dosage and gradually increase it until you get your desired results.
Cannabis Home Delivery Services Likely to commence in Massachusetts
The CCC has agreed upon setting up a substructure for beginning cannabis home delivery services in the state of Massachusetts. The organization has presented a draft highlighting a timeline and new industry rules for starting the delivery services. Operations may begin in about a month.
The Commission has proposed an outline that would permit two types of delivery licenses for operators. Its limited delivery license would allow authorized personnel to make deliveries from CCC licensed retailers and dispensaries. Furthermore, the wholesale delivery license would allow operators to buy cannabis in wholesale directly from the cultivators. The purchased commodities will be allowed storage at a CCC approved warehouse facility. Warehouses are required to have a docking facility or sally port for a secure loading of delivery vehicles.
In additio.3n to these requirements, the CCC’s delivery draft regulations has fixed a $1,500 application fee for the licenses. Along with this, a $5,000 annual license fee for limited delivery licensees and a $10,000 annual license fee for wholesale delivery licensees is also proposed. As per the initial drafts, the CCC has decided to relinquish the application fee and first year license fee for limited delivery licensees. In the second year, the fees will be halved.
Chairman Steven Hoffman has pushed the Commission to provide finalized delivery regulations by October 20th. In the light of this, the CCC will shortly open a public comment period on the delivery regulations.
What would these cannabis delivery licenses mean for licentiate?
These delivery permits would allow licensees to supplement retail stores and provide new channels of recreational marijuana purchase.. Obtaining delivery licenses would provide a boost to small businesses. This is because the barriers to obtaining retail licenses are much more pronounced than the delivery category.
According to Commissioner Britte McBride, who wrote the regulations, “What we’ve done in addition to creating those two license types is also to establish new fees and fee structures, to require warehousing for wholesale delivery licensees, to authorize white labeling for wholesale delivery licensees. We’re defining specific operational requirements that will be in addition to the general operational requirements, and we are amending existing relevant regulations to incorporate the license types and the activities that they can undertake,”
Is it too early to allow cannabis home delivery services?
Is the requisition of cannabis really going to be just a phone call away?
For marijuana opponents, the idea of getting such convenient doorstep delivery is surely not going to be taken in good spirits. According to ballotpedia, about 46.34% of voters in Massachusetts were against the legalization of marijuana and its regulation as alcohol in 2016. For this particular segment of the population, home delivery of the drug may be an advancement that is taking place too fast. There will be concerns related to identity thefts, rise in crime rates, and products falling into wrong hands, particularly children.
Contrary to this, for the advocates of marijuana, this advancement of licenses would allow them a much needed convenience. Look at this from the perspective of bed-ridden medical marijuana patients. Leaving beds, let alone houses, is a painful endeavor for this segment of marijuana users. If other medications are already being delivered to their doorsteps, why cant medicinal marijuana join the delivery market?
For the recreational users, home deliveries might prove catalytic in reducing the stigma attached to marijuana usage. For years, marijuana has been shelled with the “not in my backyard” attitude. Despite of being advocates, most marijuana users have had to hide their association with the drug to curtail themselves from the society. If home delivery vans arrive right at the door step, it may lead to a normalization and acceptance of marijuana at some point.
Why allow delivery now?
Delivery of medical marijuana is not a new concept, even in the state of Massachusetts. Almost six authorized medical dispensaries have provided this service to registered patients since 2018.
If more licenses are granted for more legal businesses, illegal delivery services may be controlled right in infancy. In addition, this will also provide low cost business opportunities to aspiring market entrants.
The government provides no support to the marijuana industry due to its illegal federal status. By creating such opportunities at the state level, barriers to entry may be successfully reduced.
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