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6 top-ranked cannabis stocks in the United Kingdom

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The use and possession of cannabis is illegal in the United Kingdom. Not only it is the largest producer in the world but also the largest exporter of legal cannabis in the world. There are many companies in the United Kingdom dealing in this business. Let us go through some of the top listed cannabis stocks in the country.

GW Pharmaceuticals

When we talk about the medical cannabis stocks of the United Kingdom, GW Pharmaceuticals surely tops the list. Established in 1998, this company has manufactured a couple of leading marijuana-related treatments worldwide.

GW Pharmaceuticals has the worth of a sale of more than $50 billion which is greater than most of the North American companies of cannabis including Tilray, Canopy Growth, and Aurora.

One of the leading producers of GW Pharmaceuticals is Sativex. It is a spray constituting THC as well as CBD. The function of Sativex is to medicate different kinds of multiple sclerosis (MS).  Furthermore, Sativex is legal in more than 25 countries. In addition to Sativex, the other leading product of GW Pharmaceuticals is Epidiolex. This product is used to medicate epilepsy in children and it is authorized in the United States of America and not in the UK.

Associated British Foods

Associated British Foods is also in the list of largest manufacturers of legal marijuana in the country. It produces a great amount of CBD-based marijuana and supplies it to GW Pharmaceuticals to produce Epidiolex.

Moreover, AB Foods is also involved in other businesses as well including agricultural and ingredients. It produces sugar, corn, and clothing as well.

Futura Medical

Futura Medical produces gels and creams which provide medications through the skin. The lead product of Futura Medical treats erectile dysfunction.

Furthermore, Futura Medical has done a collaboration with CBDerma Technology to produce CBD-based items for patients.

Zoetic International

Zoetic International was known as Highlands Natural Resources, an oil and gas company, before its transformation into the cannabis business. This company discovered gas in one of the states of the US which had pure nitrogen and hydrogen. They used these gases to make fertilizer which enhanced the yields of marijuana facilities.

Zoetic International owns two CBD-based products brand in the United States, which include vapes and soft gels. Additionally, the company has initiated the sales of marijuana tinctures online in the country and it is planning to expand it across Europe.

Integumen

Integumen has acquired Rinocloud, which provides a platform for automated and real-time skin testing digital service. To enhance the quality of cosmetics and soaps, the company has collaborated with a small firm of blue-chip in the United States of America.

Integumen has signed many deals to produce CBD-based products and test its platform.

AfriAg

AfriAg is a firm serving in logistics in the agricultural sector worldwide. Additionally, it has announced to enter in the medicinal marijuana market. According to the sources, AfriAg is planning to apply for a license from the UK to allow it to grow and produce marijuana for medical purposes in the country.

It has already invested in the Apollon Formularies, a medicinal marijuana firm of Jamaica, and has made many harvests successfully.

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Cannabis

Long Term Use of Cannabis Could Affect Your Social Behavior, Here’s Why

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While there’s no denying the fact that cannabis has tons of medical benefits, extended exposure to it could have serious social behavioral repercussions.

In a nutshell, long term use of cannabis affects the ability of astrocytes to manufacture food for neurons from glucose. This reduced food production compromises on the neural function, which appears to have adverse effects on the person’s behavior.

The way long term cannabis use alters behavior appears to have a direct link with the cannabinoid function. While it is mostly observation and researchers know of no concrete mechanism yet, cannabis consumption could lead to reduced social interactions and withdrawal.

A deeper understanding of the cannabinoid receptors could prove fruitful in determining the relationship between cannabis and social behavior.

The role of cannabinoids

The role cannabinoids play is much more important than ever since some of these receptors are also present on the mitochondrial membrane. ‘Mitochondrion is the powerhouse of the cell’, is a statement almost everyone is well familiar with. If something were to happen to the mitochondria inside the cells, it could very well reflect on the person’s behavior.

Also read: Cannabis Maybe a Cure For Various Cancers

Mitochondria metabolize glucose into lactate, which neurons use as food. The main psychoactive compound in cannabis is THC. A better understanding of the relationship between the two could open doors to new possibilities.

Observations in mice reveal that if astrocytes are exposed to THC for an extended period of time, the cannabinoid receptors present in them start a chain of reactions that in turn lead to glucose metabolism dysfunction.

Therefore, there’s less available ‘food’ for astrocytes. This is like operating some heavy machinery with dry cells from a TV remote. Observations made suggest that this lack of ‘food’ has a direct impact on the subject’s behavior.

Moreover, in extreme cases, exposure to THC hampered social interactions for up to 24 hours.

While uncontrolled use of cannabis could be dangerous, controlled use with appropriate observations could very well be used to deal with some behavioral problems more easily and effectively.

The debate over therapeutic cannabis is yet again a hot topic. A better understanding of cannabis’ effects on the human body could help in finding the optimal solution.

However, for now, a simple rule to keep in mind, excess of everything is bad.

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Pennsylvania: Lt. Gov. Fetterman Urges Cannabis Legalization

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Lt. Gov. John Fetterman urges Cannabis Legalization to reduce the impact of the budget deficit. Due to the COVID-19 pandemic, the economy has suffered a lot. Due to the economic setback, the state faces a budget shortfall of $3.2 billion.

Fetterman tweeted to support the legalization of recreational marijuana. He says that legalization of marijuana will open new avenues to generate tax revenue. According to Fetterman, the legalization of marijuana could generate half of this COVID-19 deficit. It will also be helpful in reforming the state prison system.

Recently, Lt. Gov. Fetterman took to Twitter in support of cannabis legalization.

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Catering For Budget Deficit

In an economy greatly hit by the global pandemic, the legalization of recreational cannabis will help providing thousands of jobs to the unemployed.

Majority people of Pennsylvania support the legalization. Fetterman is of the viewpoint that cannabis in Pennsylvania could bring up to 500 million dollars into the state’s coffers which is why he urges Cannabis Legalization.

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Pennsylvania has a big marijuana market. Its legalization will allow Pennsylvania to stand on its own feet.

Some other politicians, however, disagree with the notion of legalization. They think that instead of adding new taxes, they should try to control the spending. The bill to legalize the adult use of Marijuana is in the committee. However, nothing can be said about the legalization with certainty.

Also Read: Police Caught 50 kgs of Cannabis from Plungington Area

However, According to State Sen. Stefano, his committee is reviewing new research. He told KDKA’s Meghan Schiller that the biggest hurdle is that there is no measurement technique for determining THC concentration in the human body. He said he’s hesitant to move forward, until there’s a way to determine the amount of intoxication.

The State Senator said that the bill was in his committee and he didn’t have plans to bring it up anytime soon. There is still room for a lot of research to be done. The decision to legalize adult-use marijuana isn’t a very wise decision without taking all the factors into account.

However, it’s research business owner Posteraro sees this as an opportunity. He hopes that it doesn’t take too much time to legalize it, because opportunities like these seldom present themselves.

Whether or not Cannabis should be legalized still remains open to debate, but there is no denying could help the nation face a huge financial deficit.

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Cannabis Rendered Helpful in Saving Lives of COVID-19 Patients

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Recent Researches revealed how Cannabis plant can help in saving lives of COVID-19 patients. The active components found in Cannabis Plant make it seem as a possible treatment for coronavirus infections.

Anti-Inflammatory Properties of Cannabis

The University of Nebraska and the Texas Biomedical Research Institute are conducting further researches to study the utility of CBD to check its utility in treating inflammation of lungs caused by coronavirus. The anti-inflammatory properties of Cannabis can be especially valuable in improving issues related to behaviour, immunity and brain.

Researchers explained that the infection is related to a cytokine superstorm, that causes symptoms like cough, fever and muscle pain. The increased inflammation can even cause pneumonia and breathing difficulties. Breathing difficulties are the number one cause of deaths due to COVID-19.

Also Read: Cannabis Found Effective in Treating Pain with Zero Side Effects

Reduction in the Amount of Cytokines

Previously, researches conducted on CBD show that it can bring down the level of several cytokines, that cause inflammation, including IL-6. It also helps in controlling interleukin (IL)-2, interferon gamma, IL-1α and β, inducible protein-10, macrophage inflammatory protein-1α, monocyte chemoattractant protein-1 and tumor necrosis factor-α. Excess of these leads to severe COVID-19 conditions. Moreover, CBD also increases the  interferons production. Interferon is a protein that prevents viruse replication and activates immune cells.

CBD’s anti-inflammatory properties have worked wonders for asthma patients by reducing the production of pro-inflammatory cytokine production. CBD also reduces pulmonary fibrosis. This condition causes scarring, thickening and damage to the lung tissue, along with making breathing considerably more painful. COVID-19 actually leaves patients with pulmonary fibrosis. This is the major reason why Cannabis can greatly help COVID-19 patients.

An insight into how COVID-19 works

Much like other respiratory pathogens, COVID-19 is also spread through respiratory droplets. However, it also has potential for contact and aerosol spread.

Coronavirus makes it way into the human body through receptor-mediation. This is done through angiotensin-converting enzyme II (ACE2). ACE2 is present in lung tissue, oral and nasal mucosa, gastrointestinal tract, kidneys, and testes.

This information opens door to a new way of hindering the spread of coronavirus. Modulation of ACE2 could prove fruitful in this regard.

Cannabis’ prospects

A special strain of cannabis can render this function. Through ACE2 modulation it could block the virus’ entry into the human body. Nipping the evil in the bud.

Basically, ACE2 acts like doorways to the virus. The main idea is to temporarily alter the extent of ACE2 gene expression. Therefore, it could very well make the human body a no entry zone for the virus. The same strain could also be used to stop the virus’ propagation if it has made its way into a person’s body.

This is where Cannabis sativa comes into play. Plants with high CBD content have been proposed as a way to modulate the ACE2 gene expression in target tissues.

At this point in time, it is more of a theory than a confirmed fact. However, it sure opens a new avenue with promising prospects. If it proves successful, the next step would be to start manufacture that particular strain into a medication.

It sure looks like CBD properties of cannabis can prove fruitful in the treatment and prevention of coronavirus. However, further research will prove whether it is the case or not.

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