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New Technology to Predict Cancer Recurrence in Melanoma Patients

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The beginning of melanoma takes place when a small pigmented spot appears on the skin. By removing the lesion, a primary melanoma can be treated but it has a tendency of reoccurrence and can spread throughout the body. A new study showed that the likelihood of cancer can be predicted after the removal of the lesion.

Despite all medical advancements, the analysis of lesion his performed in the same old way. Generally, molecular diagnostic labs have many advances for the detection of other forms of cancer but for the skin lesion cancer the way of diagnosis is very simple. The diagnosis is based on the thickness of the melanoma and microscopic features.

A patient with thinner melanomas is considered to be normal and the T stage from 1 to 4 is assigned. The complete details of this study are published in Nature Cancer.

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The researchers from the Brigham and Women’s Hospital in collaboration with international colleagues showed a new technique about the reoccurrence and spread of melanomas. It leverages the sequences of DNA for predicting the possible factors involved in the reoccurrence and spread of melanomas.

Thomas Kupper who is the chairperson of the department of dermatology at the Brigham that there were no treatments available for metastatic melanoma 10 years ago. But now it is possible to treat the patients who have metastatic melanoma and these treatments can be given at the primary stage of the disease. It is important to have a clear idea about the patient’s progress report after giving the new immunotherapy treatments, so we can modify the treatment.

There are immune checkpoint inhibitors that can reinitiate the immune response through T cell against the cancer cells. These inhibitors have changed the results and options for the patients in which cancer has spread throughout the body. Immune checkpoint inhibitors can start dramatic responses such as long-term remission in the period of curing a patient.

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Kupper and colleagues wanted to know about some measurable features of T cells. These features are used to check the predictions of the reoccurrence of melanoma in the removed primary melanoma and disease-free patients. Scientists study T2, T2, and T4 primary melanoma as the T1 are rarely metastasized melanoma.

They also face difficulty in finding the sample that was enough for results because skin lesion surgeries are usually performed at private clinics and ambulatory clinics. So, the concentration of the specimen is not available in the hospitals. For resolving this issue and for sharing the resources researchers collaborated with colleagues of the Melanoma Institute of Australia and the Zealand university Hospital in Denmark. The sample size for the analysis contains more than 300 patients from different areas.

The samples of primary melanoma patients with progress have been compared with those patients whose primary melanoma did not show any progress. For analyzing the T cell range of tumors, Adaptive Biotechnologies performed high throughput DNA sequencing. It was found that out of all identified variables the T cell fraction (TCFr) was an independent and strong predictor for the patients’ progress condition.

Patients with the same lesion thickness were more at the risk of developing metastatic disease. If the TCFr value is lower than 20 % in the patients, then they are more at the risk of disease progression. On the other hand, if the TCFr value is more than 20% then the risk of disease progression is low in patients.

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 The test used in this study is not available at the commercial level for clinical use. It is only used for research purposes. The authors said that the study is retrospective because it took the sample and data of patients that are already available. While the prospective study is that in which data for outcomes is not known and further tests are needed for validation.

Kupper and colleagues imagine that if a test could bring to the clinics then it will improve the patient care and strengthen the results. The test is elegant, simple and quantitative. These types of tests will help us in the future to modify the treatments according to the situation. If the patients have high TCFr then we will benefit him with checkpoint inhibitor therapy. If the value is low in patients, then more interventions are needed.

 

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Resurge Reviews Reveal Important Information on its Benefits

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Resurge Reviews

Resurge is the latest addition in the best fat burners list of 2020, as people are purchasing Resurge more than all other popular products for weight loss. It is currently the most reviewed fitness formula on the market, revealing important details on all the promised benefits.

For almost everyone, weight loss is a ‘low-calorie diet’ and ‘two hours at the gym. But is it really that simple and anyone who does these two things loses weight? Maybe not.

More than 70% of obese people report that the conventional weight loss processes are unable to help them which is why they switch to rather controversial products with the hope of weight loss. These shady products cause more harm than benefits and leave them with nothing but side effects. Having said this, a product like Resurge seems like a light of hope for everyone who is going through the same problems.

The risk-free formula of Resurge starts working within a few days of usage. Where other products take months to show results, the users of Resurge experiences notice visible changes in their bodies within a few weeks.

Who would go for extreme body transformations or expensive products when a simple dietary supplement is doing the same? That’s why the number of Resurge users is increasing day by day along with its popularity and demand. But what makes it such an effective product? How does it help in weight loss? Here is everything on resurge that could help you to understand this product.

Why use Resurge?

What would you do if you come to know that there is one simple product that could help you to achieve your weight loss target? Would you go for it or continue doing the standard weight loss practices despite experiencing no results?

Resurge is a dietary supplement that is designed to make its user lose weight, in a natural way. Now, this ‘natural weight loss’ is often associated with a number of products but none of them explains what is it and how does it help.

A natural weight loss is when the body, on its own, loses weight. The next question that comes to everyone’s mind is that; is it possible to lose weight on your own? Of course yes, all body systems are in a perfect balance and each one of them functions to ensure this natural equilibrium. Just like breathing, thinking, blood pumping, metabolism is also a natural process through which the body sheds excessive weight and maintains a healthy weight for long.

When metabolism is affected, the natural weight balance is also disturbed which is when Resurge pills start taking their action.

It suggests that Resurge pills work on metabolism and improves it so that the body starts burning the fats all by itself. It is true not only for a total body weight loss but also for stubborn fat spot reduction like in case of belly fat, heavy thighs, or hips fat. In this way, it trims the excessive fat layers around the body, improves the health of its user, and saves him from the risk of certain obesity-related diseases such as heart diseases, diabetes, etc.

ALSO READ: Honest Success Stories of Resurge on its Official Website here

More than half of the world’s population is struggling with their weight right now and even the obesity trends in children have been increased over the last few years. It needs a complete lifestyle and dietary shift along with using a weight loss promoter product like Resurge, for maximum benefits.

Ideally, resurge pills should be used by adult and otherwise healthy individuals who are ready to start their weight loss journey. If there is a pre-existing medical condition, the best is to get its treatment first and then work on the body transformation with Resurge.

Who has created it?

Resurge has been created by John Barban, who is a famous name in the health and wellness industry. By profession, he is a fitness coach who specializes in sports nutrition and training. Resurge is a mix of his years-long experience as a weight loss coach while working with prestigious companies like BlueStar Nutraceuticals, MuscleTech, Slimquick, and others.

By academics, John is a graduate of the University of Guelph majoring in human biology and nutrition. He completed his Masters and various short courses from eminent universities such as the University of Florida. Having such a learned background, a product designed by him doesn’t leave a suspicion on the product’s quality and efficacy.

What is Resurge’s deep sleep action?

Resurge is often linked with its famous ‘deep sleep weight loss’  which sometimes confuses the new users. How is it possible to lose weight while you sleep? Common sense would probably say no, but John Barban has practically shown that it is indeed possible.

Metabolic regeneration is a restorative body function by which it repairs the damages and disturbances naturally. If necessary, it regenerates the cells and makes sure that nobody’s function is impaired or stopped.

This regeneration takes place by a special hormone, called Human Growth Hormone (HGH) which improves metabolism, prevents aging, boosts immunity, regrows body cells, increases libido, and burns fat. All these functions are managed alone by this human growth hormone which suggests its high significance in human health.

What would happen if this human growth hormone stops working? Is hormonal imbalance related to weight loss? This is true because aging is the biggest risk factor for limiting the production and release of this hormone, which is why people experience compromised immunity, libido, and limited growth in older ages. But surprisingly, aging is not the only factor in disturbing the human growth hormone levels. It is also affected by poor lifestyle and dietary habits which is why all weight loss plans emphasize healthy eating and doing exercise regularly.

In this situation, Resurge capsules make sure that the body is not going through trouble while initiating the natural recovery process. Typically, inflammation, stress, oxidative damage, limited blood supply, and other ‘minor’ problems like these affect the natural recovery. Using resurge pills daily reduces stress, improves blood circulation, boosts immunity, and regulates a healthy hormonal level, all of which aid in weight loss, indirectly.

The deep sleep weight loss by resurge is when the user is experiencing a peaceful sleep and his body is going through this restorative process while being on auto-healing mode. It also prevents sleep-related disorders i.e. insomnia and makes sure that the user wakes up fresh the next day and starts taking his daily tasks more responsibly and actively.

Meanwhile, the weight loss is initiated on its own without doing anything extra. It suggests that resurge is a multi-action formula that has remarkable health benefits in addition to weight loss alone. It works on all connecting problems with weight loss and improves them, as a result of which the body loses weight with resurge’s deep sleep action.

These methods don’t address the root cause behind the weight gain. John Barban’s Resurge weight loss supplement identifies sleep deprivation as the root cause which normally gets overlooked. He scientifically establishes the link between sleep and weight gain, showing how the Resurge weight loss supplement can solve the weight problem by restoring deep sleep.

Must Watch: A Complete Video on Clinically Proven Weight Loss Benefits of Resurge

Ingredients inside Resurge supplement

Resurge uses 100% natural ingredients inside it. The reason why is it promoted as a ‘safe’ and ‘effective’ product with weight loss benefits is because it uses only scientifically proven ingredients in its formulation. Each one of these ingredients is extracted from premium quality sources and combined as a non-GMO product, which is the perfect safe for everyone. The ingredients inside the resurge supplement are as follows.

Melatonin

It is a strong anti-oxidant that ensures good eye health, stomach health, and sleep regulation. Having it inside Resurge’s formulation is responsible for initiating the deep sleep action.

Ashwagandha

This natural ingredient has proven health benefits for stress relief and prevents anxiety-related disorders.

Hydroxytryptophan

It improves and enhances all the effects caused by melatonin for promoting weight loss by deep sleep.

L-Theanine

It improves heart health, anxiety, and stress levels.

Magnesium and Zinc

These minerals are essential to improve sleep, blood regulation, metabolism, and blood circulation.

Arginine and Lysine

These two ingredients are responsible for maintaining the human growth hormone levels inside the user’s body. It also initiates the restorative and regenerative process of the body’s natural healing.

All these up-listed ingredients are safe for human health. Their roles in sleep regulation, fat burning, and immunity boost are extraordinary which is why they are picked to be inside resurge supplement.

To manufacture this formula, John collaborated with a top-quality production unit to prepare the fully loaded resurge capsules and pack them inside a sealed bottle. This bottle comes with complete user guidelines to educate the new users on its dosage and use.

The exact information on its formula is not made public for obvious reasons. More than just a weight loss pill, resurge is popular for an all-in-one dietary formula for good health and immunity.

Benefits of using Resurge pills

As it is clear so far, Resurge is a fat burner but unlike other typical products, it has a broad spectrum of benefits to offer. Resurge user reviews suggest the following benefits of this dietary supplement.

  • Improvement in metabolism and a complete breakdown of food.
  • A control over unhealthy hunger pangs
  • Reduced food cravings especially of sweets, treats, fast food and candies
  • Improvement in sleeping time, quality and relaxation
  • High energy levels that last throughout the day
  • Better and improved immunity and low risk of weight-related diseases
  • Improvement in skin, hair and nail health
  • Complete body transformation by melting the stubborn fat layers
  • Increased libido and sexual strength
  • Improvement in eye health
  • Better focus, concentration and cognitive benefits
  • Zero side effects even when used for a long term
  • 100% natural formulation that is vegan friendly
  • Made in the latest and high-quality manufacturing unit
  • Comes with a money-back guarantee

Who should use Resurge Supplement?

Ideally, it looks like Resurge is only suitable for people who want to lose weight. But going through resurge user reviews tell that people are using it for maintaining weight as well, once they have achieved their weight loss target.

In addition to this, it is also helpful for a person who is suffering from sleep-related problems, work performance problems, and low immunity. As it is made of natural ingredients, it is safe for everyone. So even if a person has no such weight-related problem but wants to upgrade his health and immunity, resurge is a reliable product to add to the daily routine.

It is even more helpful for middle-aged people who are experiencing aging effects physically and mentally and are looking for something which is not a medicine but improves their health.

Resurge pills work even better if a user incorporates them in a healthy diet and light to a moderate exercise routine.

How to use Resurge pills?

Like other dietary supplements, resurge pills are to be taken with water. The complete dosage guidelines are mentioned on the label and every user is advised to go through them before taking the pills.

The good thing about resurge weight loss is that it doesn’t require the user to follow a crash diet or spend hours at the gym. However, switching to healthy alternatives accelerates the benefits of resurge and the user is able to get its results fast.

Resurge has helped hundreds of people to completely upgrade their lives and achieve their dream weight. However, it needs regularity of usage to show these benefits. Use it for at least four weeks to expect any results.

Side effects of Resurge

Everything inside resurge is taken from natural ingredients and natural ingredients are generally safe for human health. These ingredients are least likely to cause a side effect which means Resurge pills have zero side effects.

Still, it is necessary to consume these pills with caution. Do not overdose, mix, or combine resurge pills with other fat burners, medicines or dietary supplements to avoid interactions. If used correctly, it can not cause any side effect in its user, even after months of using it.

When would you see the results?

The online Resurge reviews tell that most of its users were able to experience its results within three to four weeks of usage. However, this is not a standard and the weight loss varies from person to person. If a user is very obese and has a sedentary lifestyle, he might take some more time to show results as compared to a person who is active and wants to lose only a few pounds.

In any case, four to eight weeks are enough for resurge pills to show their effects. This process would be slow at first but it accelerates as the user gets used to his new lifestyle and habits.  Just to add, resurge has no side effects and is 100% safe for all users.

Pros and cons of Resurge

PROS

  • Fast-acting formula
  • Natural supplement
  • Risk-free product
  • Easy to use
  • Affordable
  • No side effects

CONS

  • Suitable for adult users only
  • Not a medicine alternative

MUST READ: Resurge Updates New Discount Bundles for 2020 – Check Price Here

How expensive is the Resurge supplement?

It looks like an expensive product but it fits the budget of all users as it costs less than $100 a bottle. It is also available in bundle offers which allow the user to buy multiple resurge bottles and stock them to use later on a discounted price.

It comes with a 60-day long money-back guarantee which ensures that the customer’s money is safe. In any case, this product goes show the expected results, every user can request a refund and get his money back within 60 days of his order.

Conclusion 

Resurge is a reliable product for overall better health that comes with an ideal weight standard. It can make a person lose weight with its deep sleep action, but there are countless other benefits that make it an effective product. It is affordable and comes with a money-back guarantee suggesting it a product that any user can trust. Right now, resurge is available on discounted bundle offers. Visit its website here for a safe purchase!

 

 

Affiliate Disclosure*

At no additional cost to you, We may earn a small commission if you decide to buy the products or services we recommended here as a part of our affiliate partnership. This only helps us maintain our website. And we only recommend quality products.

Disclaimer*

Please note that any guidelines and advice given here are not a substitute for medical advice. Please consult your physician if you are under medication or have doubts following the advice/instructions given. Individual results may vary. All images used are for illustration purposes only.

 

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General News

3 Coronavirus Myths Debunked

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The global pandemic has caused a global lockdown and turned every one to their phones, and therefore social media. However, social media hasn’t been presenting the most reliable information about the COVID-19 pandemic, with its misleading posts.

Protective badges

There are “protective badges” that are marketed around the world, with the claims that it will ward off viruses. Many of the badges also highlight a white cross design. These specific badges are erroneously sold as “virus stoppers” in Russia. A few members of the Russian parliament were also seen wearing it at a recent conference of the State Duma.

The US Federal Drug Administration (FDA) however, has called all claims regarding the badges as a safeguard against COVID-19, “fraudulent”. BBC News Russian questioned MP Andrei Svintsov, why he wore the badge. He reportedly said that despite being uncertain about the effectiveness of the badge, he hasn’t contracted any virus. He further added that he has been following all guidelines on the internet (Vitamin C and chewing ginger), true or not, just to be safe.

President Vladimir Putin’s spokesman Dmitry Peskov was reported wearing alike merchandise. However, he confirmed that he was infected with COVID-19 and is currently hospitalized.

A biochemist and Associate Professor at Nottingham University, Dr. Wayne Carter also had something to say. He stated that the badges are ineffective as a protection against COVID-19. He further added that the infection is caused primarily by the inhaled or ingested infected droplets from sneezes.

Cannabis as a treatment

While thousands of articles have been published online regarding cannabis as a treatment, many have made misleading deadlines. It is true that many trials are currently taking place around the world. This includes Canada, Israel, and the UK. All these countries are trying to investigate the effectiveness of cannabis as a treatment.

Medical cannabis is already known to reduce inflammation. This useful property could potentially treat cytokine storms that are the deadly immune response sometimes shown by the most infected COVID-19 patients.

However, it is important to recognize that these trials are still at an initial stage. Hence, it would be too soon to form conclusions regarding the effectiveness of cannabis as a treatment for coronavirus.

Facebook flagged one of the articles about one Canadian research, due to some misleading information. One of the authors of this research had spoken to the PolitiFact website. The author stated that the headline claiming cannabis as protection against the virus was “an overstatement”.

The potential of cannabis to be used as a treatment for several conditions has gained popularity over recent years, with mixed evidence.

The origin of the virus

There has been speculation online regarding where did the coronavirus first emerge. A Chinese state media outlet recently posted a video. The video suggests that China is not necessarily the origin of the virus solely because the first infected case was reported there.

The video referenced an Italian scientist’s statements n a US radio interview. The interview was regarding the unexplained pneumonia cases in Northern Italy, at the end of last year. The narrator stated that the virus was possibly circulating in Italy before the eventual outbreak in China.

BBC’s China Media Analyst, Kerry Allen stated that the way China has recently increasingly ramped up the rhetoric, it could imply that it is not the origin of the virus. However, there is no scientific evidence for this idea.

It is possible to track genetic information and its course of mutation over time, to date and confirm the origin of the coronavirus.

A molecular epidemiologist at the University of Basel, Dr. Emma Hodcroft had spoken about this matter. She stated that despite the proven possibility of samples in the US and Europe linking back to the initial genetic sequencing in China, these versions have further mutations. She says that there is currently no evidence to support an alternate origin of the virus.

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WHO Warns of Mental Health Crisis – COVID-19 “May Never Go Away”

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While there have been gradual ease in the lockdown restrictions in some countries, that were originally imposed in an attempt to stop the novel coronavirus from spreading, the WHO has warned that the virus may never be wiped out entirely.

It was warned by the World Health Organization (WHO) that the coronavirus “may never go away” with the prediction by experts about un upcoming global mental health crisis that will be caused by the pandemic.
On Wednesday, predictions of the expected duration of the circulation of coronavirus were warned by the global health body and further called for a “massive effort” to overcome it.

According to the WHO’s emergencies chief, Michael Ryan, this is a new virus that is entering the human population for the first time and consequently, it is incredibly hard to predict how long will it last. He continued that it is important to focus on and understand that it may never go away and be another endemic virus in our communities. He further added that dates and promises cannot be announced for this, and there is ambiguity regarding the virus settling into a long problem.

Another looming crisis was warned, according to a report by the WHO’s mental health department to the UN. According to the department’s director, Devora Kestel, psychological distress could be potentially caused due to the isolation, fear, uncertainty, and the economic turmoil surrounding us.

She further added that an upsurge in the severity of mental illness, with the inclusion of children, young people, and healthcare workers, could be expected due to the present crisis. She continued that due to the severe impact on the mental health and wellbeing of whole societies, owing to the crisis, there is consequently an urgent need to address this.

These statements came in after Russia had 242,271 confirmed COVID-19 cases, making it the second country in the world with the highest number of infections, behind the US with just under 1.4 million. While there are 2,212 COVID-19 deaths in Russia, authorities have ascribed over 60% of COVID-19 deaths in April to other causes. The center of the country’s outbreak being Moscow has held 1,232 of those deaths. However, any falsification of the statistics was denied by Russia’s health minister, Tatyana Golikova.

In the US, according to President Donald Trump, warnings from his top infectious diseases expert were “not acceptable”, regarding the dangers of lifting the restrictions too soon. Furthermore, Anthony Fauci’s caution o the reopening of the economy and schools too soon was indeed surprising for Trump.

According to Trump, he felt that it was an unacceptable answer, especially regarding schools, and that the country has to resume its normal state as soon as possible and it will not if the schools are closed. He further added that the only acceptable situation would be if classes were not held by professors or teachers “over a certain age”.

With the prediction of a “significantly worse” US recession in comparison to any downturn since the second world war, along with present record job losses and wore ahead, by the head of the Federal Reserve, Jerome Powell, the apparent widening gap between the two men came on a day of more sobering economic warnings.

According to Powell’s statement in a webcast speech, the path ahead seems to hold uncertainty and is also subject t significant downside risks. Powell has also rejected the suggested use of negative interest rates to aid recovery, by Trump.

It was cautioned by the US Treasury Secretary, Steven Mnuchin, how waiting too long for the reopening of the economy, could give rise to severe economic damage, along with the created health impact. Moreover, global infections from the virus have almost reached 4.36 million, which accounted for nearly 300,000 deaths.

 

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