Inflammation, although a life-saving immune response, can also range from unpleasant to downright life-threatening. When a body is injured or infected, the white blood cells rush to the affected area to release signaling proteins for protection, while also pushing out potential pathogen, and then start the healing process.
However, blood flow and spark fluid secretions are increased by these proteins, which cause redness, swelling, and pain, which is inflammation. Inflammation is commonly caused by the false identification of harmless substances, even our tissues, by the immune system, which in turn produces painful and often chronic conditions like arthritis, ulcerative colitis, skin conditions, asthma, and general soreness and joint paint.
Mass-market drugs by the dozen are used for the treatment of inflammation, including over-the-counter aspirin, ibuprofen, and naproxen, that although reliable and effective, carry side effects. Furthermore, herbal and natural remedies have also gained popularity in recent years.
However, even the most popular inflammation treatments have their side effects such as ulcers, liver damage, and kidney damage that can be caused by taking high doses of Advil – with the active ingredient ibuprofen, over long periods.
Furthermore, fluid retention, high blood pressure, mood, and memory swings, and hormonal imbalance, can be caused by steroids – even in the short-term.
Meanwhile, all kinds of inflammation are shown to be alleviated by medical cannabis, which also works in ways that are different from conventional drugs. Cannabis compounds have been shown to suppress cytokines and chemokines – the inflammation-causing proteins, unlike the hormone-mimicking steroids and ibuprofen, which works by blocking prostaglandins (released in the brain in response to injury).
National Institutes of Health funded a comprehensive scientific peer review that was published in the journal, Future Science, in 2009, that explained that compounds in cannabis can identify when and where the immune system is over-reacting, and can hence help down-regulate those responses at the site instead of throughout the body.
The effectiveness of cannabis in particular for inflammatory bowel disease (IBD), is singled out in the review. This disease, not limited to, can include ulcerative colitis and Chrohn’s disease.
Regulation of the tissue response to excessive inflammation in the colon has been shown by cannabinoids. The results suggesting the modulation of the physiological activity of the cannabinoid system during colonic inflammation could potentially be a therapeutic tool for the treatment of several diseases.
130 clinical studies – that mostly involved lab mice, and similar academic reviews and papers are cited by the review. The review concludes that receptors in the endocannabinoid system, are found on the immune system, which is why cannabinoids can play an important role in the regulation of the immune system.
Despite the promising research, clinical trials involving humans have not been performed. Dr. Sue Sisley, the pioneering medical researcher with a groundbreaking study of cannabis for PTSD, has also shown agreement to the general findings of the 2009 review. Sisley’s research, placebo-controlled, blind clinical study that involved more than 70 former US soldiers for their response to cannabis therapy, will help understand the effect of cannabinoids on inflammation in the human body.
According to Sisley, although they have not quantified the degree of anti-inflammation, drawing blood for markers for inflammation, and measuring it pre-treatment and post-treatment, can help see if cannabis has an impact on the inflammatory process.
The results of Sisley’s research will not be revealed until it is completed later this year or early next. However, a positive outcome could cause renewed interest in further exploration of the development of cannabis therapies for inflammation, including the different consumption methods, strains, and terpene profiles that will be best suited for certain types of inflammatory response.
However, Sisley has explained although it is believed that strains high in the terpenes Myrceneand Pinene may have the highest anti-inflammatory effects, there is no proper evidence to support this.
Good news for Sciatica patients: CBD oil relieves the pain
The recent studies on CBD oil have unfolded its utility in various fields of medicine. Researches on the effects of CBD oil on sciatica patients show that they can prove to be very useful in its treatment. The results have shown that the oil can work wonders to alleviate the Sciatica pain.
What is Sciatica?
Sciatica is a severe pain caused by disruption in the sciatica nerve. Anything that disturbs the nerve results in extreme and sometimes, unbearable pain.
Sciatica is a nerve that starts at the lower back and extends through the hips and legs to the toes. It sends messages from the brain to the legs via spinal cord. Since, it is a long nerve, patients usually complain of the pain at the lower back, hips, legs and heels.
A compression on the Sciatica causes this severe pain. The major causes of compression are a herniated disk, bone spur on the spine or narrowing of the spine.
What is CBD oil
CBD (Cannabidiol) is a chemical compound that is derived from the Marijuana plant. It relieves the pain without causing any psychoactive or mind-altering effects. CBD oil is made by extracting CBD powder from the marijuana plant. Coconut or olive oil is mixed in it for better application.
The recent researches on CBD oil have revealed its anti-seizure, neuroprotective and pain relieving properties. Due to its wondrous effects on human body, many celebrities advocate for CBD.
Utility of CBD oil for Sciatica patients
CBD oil works by increasing the number of pain modulators that stimulate a response to the pain. Our mind has cannabinoid receptors that modulate the pathways that stimulate a response to the pain and negative emotions.
As sciatica pain arises, the CBD oil applied on the respective part works to reach the brain in order to stimulate a faster response to the pain.
While the Sciatica is a very painful condition, it is mostly treatable with medicines. However, most pain relievers have side effects that cause harm in the long run. In contrast, CBD oil works naturally to enhance the receptors with minimum side effects.
Best CBD oil to relieve Sciatica
Every person’s reaction to different types of CBD oil varies from the other. One cannot say with surety, since what works for some might not work for the others. This is primarily because every person has a different set of genetics, general health and tolerance.
Natural and organic remedies take time to show their reaction. While CBD takes some time to relieve the pain, it is undoubtedly one of the harmless ways to do so.
CBD oil works best when used with the consultation of a doctor. Before buying, one should make sure that the oil contains laboratory verified ingredients.
Who owns the Suspicious Marijuana Farm Near Middleton Home?
The Police discovered a Marijuana Farm near Kate Middleton’s family home in Buckleberry in Berkshire. A power outage led to the discovery of the illegal farming of marijuana right next to Middleton’s 18 acrea estate, on Thursday.
The Middleton Estate
Kate Middleton’s parents, Carole and Michael Middleton, own a £4.7 million Grade II Manor house in Buckleberry in Berkshire. The purchased this property back in 2012 after moving from their £1.5 million house in the same village of Berkshire. The 18-acre estate consists of 7 bedrooms and 5 reception rooms. Carole and Michael moved here due to the better privacy and security this house offered.
The Middleton Family House holds great importance for the Duke and Duchess of Cambridge. The Duke and Duchess have spent a lot of fun moments at ‘The Manor’. All the sweet memories make The Manor a strong fort to hold.
Discovery of the Marijuana Farm
Upon calling, people from the electricity board came to solve the electricity power situation. The workers from the electricity board discovered the Marijuana Farm on the Wednesday night. They immediately brought this to the attention of the police. The police raided the area on Thursday and found an empty Cannabis factory.
A witness reported that about 6 vans collected the content inside the potential cannabis factory. The police has taken all the evidence for further investigation. The Police is investigating this case under the top priority badge. They have found some evidence that the empty and abandoned factory was previously being used as a safe space to make drugs from cannabis.
Until now, no arrests have been made and people are clueless about the owner of the factory. The police has asked the public to contact police if they have any information regarding the suspicious factory hidden in the barns. The investigating officer told the media that they are still carrying out an investigation. They are confident that they will soon get to the bottom of this matter.
As suspicious as it might sound, there is no confirmation to it. Kate Middleton is the Queen of Grace and her family is an epitome of class. The rumors about the Cannabis Factory being owned by the Middletons are circulating however, it seems nothing but a rumor. Royal family has always been subjected to such fake news every now and then. Previously rumors about Kate’s fourth pregnancy were also in the air and Kate having marital issues with Prince William also surfaced.
While the Police and CID are working hand in hand to solve the mystery of the Cannabis factory and marijuana farm right next to the Middleton Family House, people are looking forward to get their hands on the latest gossip.
COVID-19 – Florida Medical Cannabis Industry Sees Significant Sales Spike
Despite the global pandemic and its consequences, the medical cannabis industry of Florida continues to flourish. Moreover, sales have increased in comparison to sales before the outbreak. Medical cannabis has gained popularity with a consistent increase in demand. Consequently, this gives an appropriate example regarding the stability of the cannabis interest despite the times of an economic crisis.
Weekly sales of medical cannabis in Florida
The first 2 months of 2020 were somewhat a state of normalcy. This was the time when the outbreak was under control. Hence, no government was forced to take drastic measures such as global lockdown, economic shutdown, etc. During the time, the sales in the dispensaries in Florida were on an average of 22,800 ounces of smokable MMJ weekly.
While these sales were during the first 10 weeks, the next week of March 13 recorded higher sales. There was a trade of 36,400 ounces during the week of March 13. That resulted in a rise of 38% in sales compared to the last week. This was the week when COVID-19 became a global concern and many countries began to issue stay at home orders.
Florida’s program records the sales figures generated starting from Friday and ending the following Thursday, to create a weekly sales report. However, the week of April 17 was another essential week to record sales. During that week, the Florida program recorded that sales in Florida resulted in a combined 39,290 ounces of the flower.
The sales during that week could be understandable due to the 2 sales boosters that aligned. The first was the initial round of the COVID-19 relief fund. During this time, the stimulus checks happened to be the primary issue that Americans’ bank accounts dealt with. The second was the cannabis holiday, 4/20, which is unofficial due to the current laws.
The market’s experience of a rise in sales on a weekly basis was not infamous. However, there was a record of consistently higher sales during this pandemic in comparison to the time before. Moreover, the rise in consumption led to this consistent period of the rise in demand. Both existing, and new patients, led to the rise in consumption.
The data available regarding the sales made in the first 10 weeks of 2020, led to the generation of an average figure. It was determined that the average medical cannabis patient obtained the average amount of 2 grams of the flower, weekly.
There was a rise in the figures during the past month in total, or the 4 weekly reports, from May 1 to May 28. The average medical cannabis patient, on average purchased 2.9 grams. This resulted in a rise of 43%.
Legal actions taken by the government
Furthermore, due to tot the global lockdown and economic crisis, there was a delay in many legal processes. However, the government recently granted permission to the medical cannabis patients for the renewal of their registrations. There were restrictions regarding the renewal which still banned in-person communication but encouraged teleconference for the renewal. However, Florida’s Office of Medical Marijuana Use did not reportedly take any substantive actions for the strengthening of the industry during a crisis as such.
The state included medical cannabis dispensaries in the list of essential businesses. The Florida government released the list early in the pandemic, in March and included the unaffected companies and businesses during the lockdown. Hence, Florida’s medical cannabis retailers continued the delivery of their cannabis products to patients.
There are different concerns that come along. The question that arises, however, is if this rise in both Florida’s medical cannabis market, and the cannabis industry generally, will be consistent or not. he cannabis industry hopes for the restoration of the economy before their added, shifting coronavirus unemployment advantages cease.
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