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Could Cannabis Be Used As A Potential Treatment for Inflamation?

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Inflammation, although a life-saving immune response, can also range from unpleasant to downright life-threatening. When a body is injured or infected, the white blood cells rush to the affected area to release signaling proteins for protection, while also pushing out potential pathogen, and then start the healing process.

However, blood flow and spark fluid secretions are increased by these proteins, which cause redness, swelling, and pain, which is inflammation. Inflammation is commonly caused by the false identification of harmless substances, even our tissues, by the immune system, which in turn produces painful and often chronic conditions like arthritis, ulcerative colitis, skin conditions, asthma, and general soreness and joint paint.

Mass-market drugs by the dozen are used for the treatment of inflammation, including over-the-counter aspirin, ibuprofen, and naproxen, that although reliable and effective, carry side effects. Furthermore, herbal and natural remedies have also gained popularity in recent years.

However, even the most popular inflammation treatments have their side effects such as ulcers, liver damage, and kidney damage that can be caused by taking high doses of Advil – with the active ingredient ibuprofen, over long periods.

Furthermore, fluid retention, high blood pressure, mood, and memory swings, and hormonal imbalance, can be caused by steroids – even in the short-term.

Meanwhile, all kinds of inflammation are shown to be alleviated by medical cannabis, which also works in ways that are different from conventional drugs. Cannabis compounds have been shown to suppress cytokines and chemokines – the inflammation-causing proteins, unlike the hormone-mimicking steroids and ibuprofen, which works by blocking prostaglandins (released in the brain in response to injury).

National Institutes of Health funded a comprehensive scientific peer review that was published in the journal, Future Science, in 2009, that explained that compounds in cannabis can identify when and where the immune system is over-reacting, and can hence help down-regulate those responses at the site instead of throughout the body.
The effectiveness of cannabis in particular for inflammatory bowel disease (IBD), is singled out in the review. This disease, not limited to, can include ulcerative colitis and Chrohn’s disease.

Regulation of the tissue response to excessive inflammation in the colon has been shown by cannabinoids. The results suggesting the modulation of the physiological activity of the cannabinoid system during colonic inflammation could potentially be a therapeutic tool for the treatment of several diseases.

130 clinical studies – that mostly involved lab mice, and similar academic reviews and papers are cited by the review. The review concludes that receptors in the endocannabinoid system, are found on the immune system, which is why cannabinoids can play an important role in the regulation of the immune system.

Despite the promising research, clinical trials involving humans have not been performed. Dr. Sue Sisley, the pioneering medical researcher with a groundbreaking study of cannabis for PTSD, has also shown agreement to the general findings of the 2009 review. Sisley’s research, placebo-controlled, blind clinical study that involved more than 70 former US soldiers for their response to cannabis therapy, will help understand the effect of cannabinoids on inflammation in the human body.

According to Sisley, although they have not quantified the degree of anti-inflammation, drawing blood for markers for inflammation, and measuring it pre-treatment and post-treatment, can help see if cannabis has an impact on the inflammatory process.

The results of Sisley’s research will not be revealed until it is completed later this year or early next. However, a positive outcome could cause renewed interest in further exploration of the development of cannabis therapies for inflammation, including the different consumption methods, strains, and terpene profiles that will be best suited for certain types of inflammatory response.

However, Sisley has explained although it is believed that strains high in the terpenes Myrceneand Pinene may have the highest anti-inflammatory effects, there is no proper evidence to support this.

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Recycling Of Tonnes Of Cannabis Containers

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Cannabis Recycling

Cannabis products formulations in solid, liquid, and smoke-able forms are available in the market for medical and recreational use. Marijuana products are kept under storage conditions set out by the manufacturer. 

 

Cannabis products come in containers of variable sizes and shapes. The material used to prepare containers depends upon the manufacturer’s choice and demand for the stability of marijuana products. 

ALSO READ: Cannabis Products Association With Perceived Risks And Availability

 

Recycling of containers is occurring for decades to reuse items or process used items into new ones. Doing so reduces pollution and helps to use one material multiple times. 

 

Returning And Recycling Of Cannabis Containers To SDQC

 

In less than 12 months, about 21 tonnes of empty plastic containers were sent to recycle to the SQDC. SQDC is the company that does the recycling under the name Societe Quebecoise du cannabis. It is a government-owned company. 

 

The company began its recycling package or recovery program in August 2020. Since August, a lot of plastic containers have gone through recovery programs, precisely 2291143 containers.

 

The use of cannabis products has hugely increased in the market. The number of marijuana containers purchased by consumers is likely to be much more than the number of containers send to SQDC to recycle. There is only a deposit on SQDC beverages included in the RECYCQUEBEC consignment system. 

 

However, there is no deposit on the SQDC containers in the system. Quebecers who do return pot containers do so not for money as they do not get money. They do so to keep containers away from trash.

 

According to the SDQC, the benefit of returning empty containers is that others materials cannot contaminate cannabis containers. Moreover, doing so ensures that these packaging materials do not end up in the blue boxes. Collecting these empty plastic packaging allows sending a uniform material to businesses that reuse it easily after quick processing.

 

What Happens To Marijuana Containers After Recycling

 

The Societe Quebecoise du cannabis signed a partnership with TerraCycle. TerraCycle is a U.S.-based recycling business company. The SQDC sends collected cannabis containers to TerraCycle and other such companies that are in agreement to recycle them. 

 

TerraCycle recycling business company focuses on using the used items to form urban furniture such as park benches, flower boxes, etc. According to some individuals, TerraCycle recycles bags that could have added to pollution or result in a landfill otherwise.

 

According to the Canadian press, it is uncertain what happens to those containers. It is also unclear how many of such packagings go into and out of the company. No one knows the exact number of plastic packaging required to produce urban furniture. Furthermore, there is little knowledge about other formulations that use this recyclable material. So far, there is no way to find it as the TerraCycle recycling business company does not respond to emails or phone calls as per the Canadian press. 

ALSO READ: Changes In Cannabis Proposed Ordinance By Santa Fe County Planning Commission

 

The SQDC, in a Facebook post on a page, announces that they will continue to work to improve the environment. They are working with a team of experts to develop an efficient action plan for cannabis containers and packaging recycling that is eco-friendlier. They are looking forward to going further with their environmental efforts. 

Environmentally Unsustainable?

Some people are criticizing SDQC for its products that are considered over-packaged or are environmentally unsustainable. Individuals complain that they have to wait in line to return the cannabis containers, and it would be much better if SQDC places outdoor bins in front of SQDC branches. Some individuals, while returning multiple marijuana containers, feel embarrassed. 

 

SQDC replied to these complaints and said that they are aware of the critical remarks. However, they cannot do much about it as they are to abide by the law. Placing outdoor bins cannot ensure control over the material. Outdoor recycling bins can increase the risk of accidental cannabis consumption in children and youth.  

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Pot Legal In NYC But Where To Buy Recreational Cannabis In New York

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Cannabis Companies Making Moves Before New York Begins Recreational Cannabis Sales

Pot products, including recreational cannabis and medical marijuana products, are legal in New York. The lawmakers have successfully approved the weed legalization and decriminalization bill. However, the administration working and policies to implement the bill is taking way too much time. 

 

The disagreements among legislators and the inability to develop a plan to implement the legislation delays implementation of the new bill. Due to delays in proceeding procedures, things have become difficult for almost everyone. 

 

Cannabis Legalization Program Of New York – A Train To Nowhere

 

Governor Andrew Cuomo and state legislatures did approve cannabis legalization and decriminalization bill in March this year. However, there has not been much progress. According to critics, the Governor is the real buzzkill on the issue. 

ALSO READ: Cannabis Products Association With Perceived Risks And Availability

Critics elaborate that Cuomo is yet to nominate an executive director for his new Office of Cannabis Management. He also has to name appointees to the Cannabis Control Board. The Marijuana Taxation and Regulation Act were passed months ago, yet the official is working slowly to appoint and name some people for the office to begin further proceedings. 

 

The Governor is delaying the procedure because the Senate members have not yet passed Cuomo’s proposed MTA legislation. Richard Azzopardi is the spokesperson of Gov. Andrew Cuomo. According to his spokesperson, there are multiple unfinished businesses in Senate. However, they will submit their nominees and names for designated positions. The spokesperson also mentioned that they hope Senate passes MTA legislation and let nominees selected by the governor implement order regarding cannabis. 

 

Politicians Against Delay In Implementation Of Cannabis Legalization Policy In New York 

 

Mike Murphy is the spokesman for Senate Leader Andrea Stewart Cousins. According to Murphy, MTA approval and nominating nominees are separate issues with no interlinkage. Thus, these matters need separate resolutions, and it is best not to try to relate them. 

 

According to State Senator Diane Savino, after observing the current situation, it is evident that the cannabis legalistic program is likely to delay for much a longer time. She added that the public and officials of New York are in between a rock and a solid hard place. 

 

Moreover, apart from the politicians, the public is angry and frustrated at the delay of matters. Residents of the state are unable to understand the logic or reasoning behind the pending situation. 

 

According to Diane Savino, legislatures or lawmakers should walk and sign a joint agreement at the time regarding the subject to settle things as quickly as possible.

 

The politician further added that nothing can happen concerning marijuana sale policy and license issuance to begin a legal business. At least until regulators develop a set of ground rules to conduct cannabis business, following legal practices is impossible. 

 

What Is More About Marijuana Policy In New York State?

 

According to Diane Savino, no operation involving marijuana is practicable unless legislators set some ground rules. Licenses to individuals to begin a legal sale, cultivation, processing, manufacturing, or distribution of marijuana is unapprovable before settling some limitations. Moreover, it is inappropriate to approve licenses without designing a regulatory system. 

ALSO READ: Cannabis Dealer Stopped By Police

Governor needs to select three people to begin the formation of the five-member Cannabis Control Board. The nominees will first get approval from the Senate to offer their services. The selection of the other two members falls on the legislatures. One member of the five-member committee will be selected by lawmakers from the Assembly and one from the Senate. 

 

The selection of nominees and their approval is the next step after passing the bill, and it took almost a year for completion. Delaying the process cause trouble for the state and the public who had to go to borders to purchase cannabis legally from neighboring states like Massachusetts. 

 

Unless the regulatory and administrative procedures are incomplete, the state is unable to generate revenue. Pending them will only slow down the development process of the cannabis business field and delay experiencing possible benefits from its tax revenue. 

Originally covered on: NYPost

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Cannabis Products Association With Perceived Risks And Availability

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Medical cannabis

Cannabis products are in use for medical and recreational purposes in more than thirty states of the United States. Some of these states allow medical marijuana products, while others allow pot for all purposes, including adult and medical purposes. 

 

Multiple studies have been conducted relating to cannabis, including pot effects and associations with other factors. Perceived risks and availability links with marijuana use disorders. Moreover, research findings can demonstrate how perceived risks can alter pot use disorders in individuals. 

 

According to a new study at Columbia University Mailman School of Public Health, perceptions of the risks and availability of cannabis influence the risk of pot use. This influence is more than the perceived risk and effect of perceived availability alone. 

ALSO READ: Marijuana Growing In Zimbabwe Is The New Farming Trend

 

The research discovers that individuals that perceive cannabis as a low-risk and available drug are more likely to use cannabis. There are some other findings too. Researchers discovered that individuals with perceptions that cannabis is high-risk and unavailable drug report fewer drug use cases. You can find research discoveries in the journal Drug and Alcohol Dependence. 

 

More About Research Regarding Perceived Risks And Availability Effects On Cannabis Use

 

Natalie Levy is a Doctoral Student of the Department of Epidemiology at Columbia Mailman School and the first author of the study. According to this research, perception of cannabis risk affects its use, frequency of use, and pot use disorders. Moreover, the availability of cannabis does influence the chances of drug use, its frequency, and marijuana use disorders. 

 

However, the findings show that cannabis risks and availability together influence pot use more frequently. The research focused on the evolution of collective perceptions of marijuana risk and availability from 2002 to 2018. 

 

Data of 949,285 participants helped in doing the investigation or survey studies. These participants are from the National Surveys on Drug Use and Health. Researchers found that over the years from 2002 to 2018, more people perceive marijuana as a low-risk drug. The prevalence of individuals who perceive pot as a low-risk drug doubled in these years. However, the influence of the change in availability perception was comparatively less evident. 

 

The joined perceptions influence was evident in these years. The percentage of individuals with the perception of cannabis as low-risk and available increased from 17% to 36% from 2002 to 2018, respectively. The number of individuals who perceive marijuana as a high-risk and available or unavailable drug decreases in these years. The percentage of people who perceive pot as high-risk and available is 26 percent. Meanwhile, the percentage of individuals that consider weed as high-risk and unavailable is twenty-seven percent. 

 

Marijuana Perception Effects

 

According to findings, individuals who regard cannabis as low-risk have reported and are likely to report six times more about pot use. Individuals with the perception of cannabis being available are five times more likely to use pot.

ALSO READ: Cannabis Legislation Back From The Dead For Better In Arizona

However, joined perceptions increase the chances of pot use. Individuals with joined perceptions are twenty-two times more likely to use marijuana. That is, people who perceive cannabis as a low-risk and available drug are more than 22 times more likely to use pot than people with the opposite perception.

 

Marijuana perceptions vary from males to females. A large percentage of the male population views marijuana as a low-risk, more available drug when compared to females. Researchers noted variations in pot perceptions in different age groups of each gender. According to the study, individuals of age 12-17 years show minimal cannabis perception differences. 

 

Silvia Martins, MD, Ph.D., is an associate professor of epidemiology at the Columbia Mailman School. She is the director of the Substance Use Epidemiology Unit of the Department of Epidemiology. She is also the senior author of the study. According to Martins, their research will open a new pathway for searching specific hypotheses. Moreover, the study highlights the importance of exploring joint perceived risks and availability on cannabis use. 

Originally covered on: news-medical

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