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Medical cannabis to reduce the use of opioids

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The researchers at the University of Georgia have come up with a new study which states that legalized medical cannabis reduces the use of opioids. It says that states that have approved medical cannabis laws saw a dramatic reduction in opioid use. The research was published in the Journal of the American Medical Association, Internal Medicine.

The researchers of the study examined the number of all opioid prescriptions filled between 2010 and 2015 under Medicare Part D. It is the prescription drug assistance plan accessible to Medicare enrollees. They observed a 14.4 percent reduction in the use of prescription opioids in the states with medical cannabis dispensaries. Moreover, the researchers found nearly a 7 percent reduction in opiate prescriptions filled in states with home-cultivation-only medical cannabis laws.

Some of the states under observation had medical cannabis laws throughout the five-year study period. On the other hand, some never had medical cannabis, and some enacted medical cannabis laws during those five years. So the researchers asked what happens to physician behavior in terms of their opiate prescribing if and when medical cannabis becomes available.

Also, 29 US states and the district of Colombia approved medical cannabis law with California being the first to approve medical cannabis law in 1996.

As per the researchers, physicians cannot prescribe cannabis because it is still a Schedule I drug. The study doesn’t aim at observing that prescriptions for cannabis go up and prescriptions for opioids go down. It only intends to evaluate the changes when medical cannabis laws are in action. Interestingly, the study reveals big reductions in the use of opioids.

Legal status of Marijuana deserves a consideration

The researchers examined all the commonly prescribed opiates including,

  • Hydrocodone
  • Oxycodone
  • Morphine
  • Methadone
  • Fentanyl

Heroin, being an illegal drug, was not included as part of the study. In the previous year, the U.S. Department of Health and Human Services announced a public health emergency with respect to the abuse of opiates. Opioid overdoses caused more than 42,000 deaths in 2016. Surprisingly, more than 40 percent of opioid overdose deaths involved a prescription opioid, according to HHS.

Between 2005 and 2011 the opioid prescription rates increased from about 148 million to 206 million. This added dramatically to the number of opioid-related deaths.

The major reason behind the lower use of opiates is the growing body of literature that suggests cannabis may help to manage pain in patients. Note that the researchers didn’t see any notable decline in the number of non-opioid drugs prescribed during the study period. These non-opioid drugs included blood thinners, flu medications, and phosphorus stimulants.

The researches admit that there is still much work to do if medical cannabis is to become an effective treatment. Research scientists are just beginning to understand the effects of cannabis and its derivatives. They believe that an effective “dose” of cannabis needs a clear definition so that each patient receives a consistent dose.

Regardless of their findings, the researchers of the study suggest quite clearly that medical cannabis and its legalization worth serious consideration. It could be one useful tool in the policy arsenal that can help to diminish the harm of prescription opioids.

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Cannabis

Curaleaf’s Cannabis Tablets out in the Markets of Florida

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Cannabis business is getting popular very rapidly across the globe as it is getting legal in several states of the United States of America. Similarly, by introducing medical cannabis tablets, Curaleaf has become the first firm in Florida to do so. And to make this medication easy to use for users, these pills are available in all the dispensaries of Curaleaf in Florida.

Curaleaf aims to expand its overall impact on the market of medical cannabis in the state. Hence, by introducing the tablets of medical cannabis, it has started its tough journey. 

Why Curaleaf is more inclined towards the medical cannabis market of Florida? 

According to an estimate, the number of people residing in Florida are almost 21 million. Among them, roughly 240,070 residents, which make up to 1.13% of the total population of the state are registered users of medical cannabis according to the Marijuana Policy Project. Seeing all these prospects, iAnthus Capital estimates the market worth $1 billion of medical cannabis by 2020. 

Marijuana Business Daily has gathered some interesting facts about medical cannabis. According to it, Florida is the second in the list of fastest-growing markets of medical cannabis in the United States of America. The daily user’s growth of medical cannabis there is approximately 609. Whereas, in Oklahoma, the daily user’s growth of medical cannabis is 641. Oklahoma is considered the first in the list of rapidly growing medical cannabis markets of the United States of America. Almost 1.6% of the total population of the state is the registered cannabis user. 

Curaleaf is planning to explore and enlarge its business of medical cannabis in Florida due to these growing investment opportunities. It has a total of 49 dispensaries in the United States and 26 of them are only in Florida.

 Competitors of Curaleaf in Florida

There are only 13 out of 22 companies that have operational dispensaries in Florida as mentioned by Marijuana Business Daily. The company leading in this venture in Florida is Trulieve Cannabis. It accounts for 49.2% of the total cannabis sold in the state. Moreover, Curaleaf stands third in the list. 

Kim Rivers, the chair of Trulieve, largely gives the credit of the company’s success in Florida to the fact that it was the first to sell smokable medical cannabis in the state at Tallahassee dispensary. Likewise, this can also be the case with Curaleaf as it is the first company to introduce medical cannabis tablets in the markets of Florida. 

Filing of lawsuit against Curaleaf

In spite of this, the shares of Curaleaf have lessened by 6% a few days ago, because of the lawsuit filed against them. In the light of this lawsuit, Curaleaf is responsible for making deceptive remarks regarding the negative facts of the material. FDA also issued a warning letter for Curaleaf due to its violations. This has led to a reduction in the share’s worth of the company.

Top competitor among cannabis companies

According to the Cannabis Market Cap, Curaleaf ranks seventh in the list of top cannabis companies. Boris Jordan, the CEO of Curaleaf, is the first billionaire in the world established from the wealth of marijuana business as mentioned by Forbes Russia. 

 

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Is Smoking Cannabis Good Enough for Men’s fertility?

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A new research suggests that smoking cannabis has a very positive impact on men’s fertility. This research published a couple of months ago, in the journal Human Reproduction. It involved almost a hundred different couples who were having medication of fertility with the In Vitro Fertilization.

According to this study, men who use cannabis have a better probability of giving birth to a baby with their partner. It is because they have greater sperm counts as compared to those who do not smoke cannabis.

The research also indicates that women who use cannabis have a higher chance of losing their pregnancy as compared to those who do not use it. Both cases are exactly opposite to each other.

What is the credibility of the research?

But only a few participants said that they had used cannabis at the time of their treatments of fertility. This fact lessened the credibility of these results. Hence, all these research works don’t mean that male partners should start using cannabis to increase their fertility. The researchers suggest that cannabis use is not necessary for the treatment of fertility in men. Also, it may not have any damaging effect on the fertility of men too.

In spite of the fact that cannabis is getting popular and legal very quickly across the globe, still, scientists have very little knowledge of cannabis impact on fertility. There must be a detailed research to clarify this confusion of the role of cannabis use.

Some facts of the research

In the recent developments, the researchers gathered information from more than 200 couples who had the treatment of fertility at the General Hospital of Massachusetts during the years of 2005 and 2017. They also analyzed information from further 220 women who had gone through fertility medication. They asked some questions to all the participants including the use of cannabis currently or ever in the past. According to the results, 61% of the men and 44% of the women claimed that they had used cannabis in the past. Only 3% of the women and 12% of the men were consuming cannabis currently.

More than 50% of women who claimed that they were consuming cannabis currently suffered from pregnancy loss compared with 26% of those who were cannabis users in the past or had never used it. The research suggests that cannabis is dangerous for the fertility of women. But as very few women were using cannabis currently in the study, this outcome may be faulty.

At the same time, 48% of the men who were cannabis users currently, gave birth to a child with their female partners compared to 29% men who were cannabis user in the past or had never consumed it.

While doing this study, researchers took care of other factors as well including age, body mass index and coffee intake.

The urologist, Dr. Neel Parekh says this new research isn’t enough to recommend men the use of cannabis before the treatment of fertility. But also, it does not harm the probability of success chances of the treatment of men’s fertility who smoke cannabis.

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How is Big Pharma Influencing Restorative Cannabis?

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The Analytics organization New Frontier Data had an examination which featured the effect of restorative cannabis on its consolidation in drugs.

The firm understands the impact restorative marijuana will have on the therapeutic industry that gets directed in all states. There will be a tremendous move in by and large pattern of complete turnover in medicinal focuses. It will change the state of the economy in important ventures.

More individuals will pick restorative cannabis over specific painkillers as an approach to adapt to incessant pain. Medical Marijuana is productive in getting various conditions. According to the researchers at Harvard; medicinal marijuana is proficient in controlling endless conditions. These incorporate interminable agony, epilepsy, and glaucoma.

Role in chemotherapy

It has been playing a positive role in managing cachexia in chemotherapy

These likewise incorporate intense conditions like queasiness and spewing because of chemotherapy. Therapeutic marijuana is additionally productive in treating psychological wellness issues. An example is Post Traumatic Stress Disorder (PTSD) and anxiety.

People in the United States, for the most part, allude to utilize restorative marijuana for lessening ceaseless pain. There is logical proof that restorative marijuana does not have enough intensity to manage extraordinary torments. This incorporates agony coming about as a result of a crack or post medical procedure.

That is the reason it is fairly effective for countering interminable psychosis that undermines a huge number of Americans consistently. This condition irritates as they become older. Marijuana additionally holds the ability to diminish torments in neurological conditions and multiple sclerosis.

In any case, on utilizing restorative marijuana, patients encountered much better productivity in their day to day lives. They significantly felt less cut off from the errands they needed to do. The favorable advantage cannabis has over sedatives is that it is more secure than other painkillers.

There is no plausibility to surpass the required portion, and it isn’t addictive like different substances. Sooner rather than later, cannabis can even supplant NSAIDs like Aleve and Advil. This is a piece of uplifting news for individuals having renal issues or ulceration, for example, Gastroesophageal Reflux Disorder or GERD.

Impact of cannabis on the medicine companies

According to a Health Affairs consider in 2016, states with legitimized cannabis had around 11 percent decrease in regular meds to manage these disorders. New Frontier Data utilized the information results to translate a conceivable impact.

The last outcome was that there could be a plausibility of having lost around $18.5 billion to the pharmaceutical business. It happened between the years 2016 and 2019. The report from New Frontier Data proposes that the United States holds around 35 percent of the pharmaceutical market over the world. It is in this way, with nothing unexpected, the biggest market around the world.

The US relies upon this industry for its economy on a considerable level. Going toward the restorative cannabis would be nothing in contrast with the impact on the all out the pharmaceutical drug market. Medical marijuana can greatly influence the highly advantageous branched markets for the industry like chemotherapy and chronic pain.

 

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