Coronavirus: U.K Approves Use of £5 Life-Saving Drug Dexamethasone
With multiple trials underway, one drug has proved to be successful. The U.K government approved the life-saving coronavirus drug dexamethasone. Moreover, the drug is cost-effective, with a price of just £5 ($6).
Researchers at Oxford University initiated a trial on the drug. The results concluded that with only a small dose of the steroid treatment, death risks for patients on ventilators and on oxygen, reduced by a third a fifth respectively. The results were published on Tuesday. This was a very significant survival rate.
The government has now authorized the treatment for use as standard care for COVID-19 patients. U.K’s chief scientific adviser, Sir Patrick Vallance reported that the drug could be ready for immediate use globally, at the government’s briefing on Tuesday.
During the daily briefing, British Prime Minister, Boris Johnson, has considered it a remarkable breakthrough in the current research conducted globally. He also mentioned that the U.K. has adequate supplies of the drug in case of a rise of hospitalized patients. The U.K. is reported to have approximately 200,000 doses of the drug in stock for immediate access.
The benefits of dexamethasone for coronavirus patients
The lead researcher of the trial is a Professor at Oxford Universit, Peter Horby. He said dexamethasone decreased the deaths of patients on ventilators, and on oxygen, by 35% and 20% respectively. Moreover, he stated that the drug saves one in eight patients on ventilators, with a cumulative cost of £40 ($50).
The drug shows a reduction in inflammation in several medical conditions including arthritis, asthma, and a few dermatological conditions. Moreover, the drug has shown reduction of the damage caused to the immune system as the patient tries to battle the coronavirus. Consequently, a cytokine storm can be fatal.
So far, this drug has proven to be the only one to increase the survival rate significantly. This estimates it cost £35 to save a life, with global accessibility. However, researchers recommend not go panic buying mindlessly. Moreover, the drug has not proved to be very helpful for milder cases of coronavirus, who require no aid with breathing.
A team from Oxford University led the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial. It began researching on six possible coronavirus treatments, in March. This also included the low-dose steroid treatment, dexamethasone. Reports state that the drug could’ve saved over 5,000 lives if it was introduced at the start of the pandemic in the U.K.
A few weeks ago, President Donald Trump was reportedly taking hydroxychloroquine. The trials for the drug had begun after the approval of the FDA. However, recently, the lack of advantageous clinical outcome, caused the trials to cease. Over 11,500 patients participated in the trial in 175 hospitals.
Researchers are constantly working on vaccines and treatments for the virus. The research included the testing of multiple drugs, such as BCG, that were used to treat earlier major medical conditions,
Miracle for developing countries
The cost-effectiveness of the drug is a huge advantage with the crashing economy globally. Additionally, as the number of hospitalized patients increases, especially for developing countries, it is harder to treat patients with the best treatments. Moreover, this drug is easily accessible in any local dispensaries and is the first to increases the survival rate.
Moreover, this drug potentially treats severe cases of COVID-19. Mild infected cases usually do not require hospitalization and usually recover in quarantine. However, severe cases require oxygen and ventilators which use hospital facilities. Developing countries are beginning to have a lack of essential medical facilities. Hence, a low-cost drug to help with severe cases is no less than a miracle currently. This drug gives hope individuals worldwide, to the much-anticipated end of the pandemic.
Luxembourg: The First European Country To Legalize Marijuana
Many of the states of the USA have legalized recreational and medicinal marijuana, but in Europe, the laws are strict. Medicinal cannabis is limitedly legal. But Luxembourg will soon become the first country to decriminalize cannabis.
On Friday, the government of Luxembourg announced via a statement that it is legal to grow and use cannabis. As per the new legislation, individuals above 18 in the county will have permission to consume marijuana. Moreover, they can grow four cannabis plants.
One household can cultivate only four plants. With the new law in action, the county would become the only county that permits the production and use of the drug without any limitations.
What Changes Can Occur By Altering The Legislation Regarding Marijuana
Cannabis will become available. Its manufacturing, development, sale, and consumption will no longer be illegal. The decriminalization of marijuana will drastically reduce the rate of the current fine.
Currently, any person possessing three grams of cannabis can be subject to a pay fine between $29 and $581. Previously, individuals were to pay for drug possession, and amerce can vary from $291 to $2910.
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The legislation of Luxembourg does permit marijuana use and cultivation but publically using the drug is still illegal. The new law allows the trading of cannabis seeds. Moreover, there are no limitations on the concentration or quantity of THC in the seeds undergoing the trading process. Tetrahydrocannabinol is the psychoactive compound of weed that can make people high.
The change in the law regarding marijuana will enable the government to clear out cannabis relating drug crimes. Another aim of making the alterations in legislation is to clamp down the drugs trade in the black market. Under the new law, Ministers will be regulating the currently illegal marijuana market.
The new cannabis policy has the support of the government. But to make it official, a vote of parliament is essential. After the voting of parliament in favor, the new proposal will get confirmation.
Chances Of Relaxation In Cannabis Law Across Europe
Luxembourg is a beautiful county with political and communal stability. People are close to their culture, and it is the best place to do business. It has the highest living standards that make it worth living.
It has a population of over 600,000 individuals and is the first to move on the forefront in decriminalizing marijuana. Overall the European continent is moving towards relaxation of cannabis laws.
In a referendum in 2022, Italy will decide about its stand on the legalization of cannabis. Whether Italy will decriminalize pot or not depends upon the number of people in favor. Once the campaign groups become able to gather 500000 required signatures to force a vote, marijuana will become legal.
So far, Italian law permits the consumption of cannabis. Thus, no fine or punishment is inflicted upon its use. Usage of medical cannabis is also legal under the law of Italy. But, purchasing, selling, and cultivating weed on a large scale is against the legislation. Drug dealers can end up in prison for ten years if found guilty.
All the actions that can lead to imprisonment under current Italian law will become legal. But only when the people vote to legalize marijuana in the referendum. After the majority voted in favor, the sale, purchase, and cultivation of cannabis will become legal.
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Other European countries are also considering changing their laws about the use, sale, purchase, cultivation, manufacturing, and distribution of marijuana. Rules and regulations regarding cannabis involving activities are likely to change in the near two to three years.
Also Covered on: CNN
NY Cannabis Board Permits Residential Medical Marijuana Production
The cannabis legalization and decriminalization bill are in practice in NY, rules for medical marijuana are set. The Cannabis Board is responsible for resolving matters involving medical and recreational weed. We are working efficiently to design regulations and procedures. The firm is determined to ensure cannabis-involved activities operate lawfully within the state.
The New York Cannabis board on Thursday issued rules to allow medical marijuana users to cultivate or produce these plants at home. Caregivers also have permission to grow medical hemp plants for their use at their residence.
NY Cannabis Board Proposal
A final decision regarding the cultivation of medical marijuana is yet to occur. Doing so will enable individuals to become self-sufficient in medical cannabis. According to the proposal of the board, they can grow several plants for personal use at home.
ALSO READ: Luxembourg: The First County To Legalize Marijuana
For now, the proposal is open for discussion to the public, and people can comment on it for a period of sixty days. The proposal permits the growth of up to six medical marijuana plants in residential space. After the closing of the commentary period of 60 days, the regulation will take effect. By the end of this period, the cannabis board will finalize the ordinance in its official language.
Since 2014, medical marijuana, despite being legal, was not available in the market. It was also not easy to access items that consisted of constituents of the cannabis plant.
People used to visit medical dispensaries and facilities to purchase cannabis for their treatment. These items are usually expensive, and there is no insurance policy that can help in paying the expenses on sales of cannabis. According to an observational finding, people purchase products from Vireo Health Company. According to the company, a patient, usually on the first visit to a nearby dispensary, spends between $100 and $350.
Residential medical marijuana growth will facilitate many patients and make it easy for them to access cannabis. Once the regulation becomes official, individuals can cultivate six plants in their private living area.
The state Senator Diane Savino also passed remarks on the rules and regulations regarding medical marijuana. According to Daine Savino, the NY Cannabis board proposes the best policy. Diane appreciates Governor Kathy Hochul and the entire team of the board in addressing the issue of medical pot.
According to Diane, the matter regarding cannabis issuance for caregivers and certified patients has been long-standing. Fortunately, the board members address the topic swiftly.
The Road To Medical Marijuana Cultivation At Residents
In NY, recreational pot legislation approval occurred in March 2021. The Marijuana Regulation and Taxation Act was also approved. The decision by the Cannabis Board to legalize medical marijuana production is the first step to putting the Act in action.
The Act does give permission to cultivate pot for medical reasons once the Board puts rules and regulations in place. According to the previous decision, the board members were to provide practical policy within six months of recreational legalization. However, Governor Andrew Cuomo neglected to appoint the board members, so the deadline passed.
Things move forward in a better way after Hochul takes control of the office and assembles it. After taking office in August, till the present, two meetings have already occurred. The Board discusses and implements rules regarding medical marijuana and recreational cannabis legalization.
According to Tremaine Wright, due to the quick action of governor Hochul and lawmakers, the medical pot program will soon expand. The expansion will lead to many other benefits and help in building a new industry. These activities will help in operating the medical marijuana industry safely. The Cannabis Control Board chair, in a statement, highlights the importance of medical pot regulations.
Originally covered on: Gothamist
Cannabis Oil Effectively Reduces Chronic Pain
The use of cannabis oil and other medical items containing marijuana legal since 2018 in the UK. However, the evidence of marijuana being efficacious has come under light recently. Researchers are discovering the effectiveness of marijuana oil in chronic pain patients.
Multiple studies occurred to determine the effectiveness of cannabis oil. Patients receiving marijuana as part of their treatment feel much better and experience improvement in their health.
Gathering Evidence Of Cannabis Oil Being Effective For Chronic Pain Patients
The United Kingdom Medical Cannabis Registry enrolls one hundred and ten patients. The purpose of enrolling these patients was to observe the effectiveness of cannabis oil. Moreover, through these patients, the impact of marijuana on overall improving quality of life was determined.
ALSO READ: New York Cannabis Board Relaxes Medical Cannabis Rules
The registry reports that enrolled patients feel much better after one, three, and six months of cannabis oil intake. They experience that their pain reduces after using medical pot. They experience comfort, and their sleep quality has improved hugely. According to the registry, there are significant improvements in patients’ health-associated quality of life.
The National Health Service of the United Kingdom has a strict cannabis oil prescription policy. It is hard for patients to get a marijuana prescription because of the strict rules of the NHS. Patients who don’t respond well to conventional therapy have access to medical marijuana. The conditions under which patients can access medical marijuana include pain sufferers, individuals with anxiety issues, and multiple sclerosis.
About sixty-five percent of the patients part of the study had never used cannabis oil or medical marijuana. The participants are primarily diagnosed with chronic non-cancer pain, neuropathic pain, and fibromyalgia.
16% of the participants suffered from fibromyalgia and 48% percent from chronic non-cancer pain. Twenty-four percent of the participants are suffering from neuropathic pain.
Experts Focus On Research
For the betterment of society and its safety, it is vital to gather research-based evidence. Doctors and scientists consider it essential to discover the realities of using cannabis before prescribing it.
Dr. Simon Erridge is the head of research at Sapphire Medical Clinics. In a statement, he said that the number of medical marijuana prescriptions is increasing quickly in the UK. In this situation, it is essential to determine the outcomes of patients. Collecting real-world practical evidence regarding cannabis oil consumption is vital.
According to Dr. Simon, this research that they conducted is one of a kind in Europe. His team will continuously review inpatients, outpatients, and marijuana products via the Medical Cannabis Registry UK. So far, the selection of observational data has occurred. In the future, more critical research, including randomized controlled investigations, will occur.
Sapphire Medical Clinics developed the registry. They survey patients suffering from various diseases receiving separate prescriptions depending upon their condition. Surveying these individuals enables us to reduce the knowledge gap.
Filling the blank space regarding medical marijuana and cannabis oil in scientific knowledge helps a lot. The study’s findings were published in the well-known scientific journal, the Journal of Clinical Pharmacology.
The research does prove that medical marijuana is effective in improving multiple conditions of people. But researchers require more research to form guidelines, funders, and licensing agencies.
Adven is a subsidiary of Curaleaf International. It is one of the largest independent marijuana companies in Europe. Adven cannabis oil was used in studies such that the average CBD dose was 20mg per day. The average THC dose that participants get is 1mg per day. Administration of cannabis oil occurs in a ratio CBD/THC of 20 to 1.
More participants enrolled in the survey process. Sapphire Medical Clinic plans to continue its survey-based research.
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