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Two Coronavirus Vaccines Prove Effective in Human Trials

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Recently, two coronavirus vaccines have proven effective in triggering an immune response in humans. According to the doctors, both drugs led to a similar response as the actual virus.

History

Coronavirus cases have been increasing ever since the virus’s outbreak in Wuhan, China last year. The novel virus belongs to the SARS family and was said to have spread from bats to humans. Soon after the outbreak, it became a global pandemic effecting a large number of countries across the globe.

The governments pushed majority of the nations into lockdown and implemented strict precautionary measures to control the spread of the disease. This adversely affected the world’s economy even causing the oil market to crash.

Various scientists and research groups have been actively working to find a treatment plan for the infection. Numerous attempts have also been made for developing a vaccine. Although, a number of potential candidates are in the human trial phases, FDA has not approved any of them yet. Researchers believe it will take a few more months for the vaccine to be available in the market.

Also read: Spain Orders Killing of 100,000 Minks After They Contract Coronavirus

Vaccine Trials

Recently two human trials testing different vaccines have produced a fruitful outcome. Both drugs were able to trigger an immune response similar to the actual virus in humans. The results showed that antibodies and white blood cell production in the body significantly increased to fight off the foreign bodies.

Source: Al-Jazeera

The human trial for the first vaccine was held in Britain. It involved over thousand adult subjects who were given a shot of the vaccine and the results were analyzed. The findings showed that the developed drug was able to induce a T white blood cell immune response. It also led to the production of strong antibodies in the body.

The second trial was held in China and involved around five hundred people. Like the trial in Britain, the Chinese study subjects were also given a dose of the vaccine. The results showed a powerful immune response in all of the volunteers.The findings from both studies were published in a science journal called The Lancet medical journal.

Future Implications of the Studies

Even if the vaccines do not prove effective in the more advanced phases, the research can prove to be an effective and important stepping stone for the ultimate development of the vaccine for the novel corona virus. Future research can work on, and improve the methods employed by the current studies to increase the probability of success in the vaccine development endeavors.

Also read: Moderna Produces a Safe and Effective Vaccine for Coronavirus

The lead authors of both studies stated that there were very few negative side effects observed in the subjects. They further added that the research is promising. However, more work needs to be done before the vaccine can be made available to the public. Particularly, the drugs need to be modified in order to reduce the intensity of their side effects in older people, who are more likely to die from the coronavirus infection.

Sarah Gilbert a co author of the study from the university of oxford said that if approved by the FDA, the vaccine can be easily produced on a large scale, given the procedure the development process follows.

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Cannabis

3 Ways To Enjoy Cannabis And Its By Products

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Cannabis Is Available In Many Forms

Cannabis is a literal treasure chest of hundreds of useful chemicals. There are so many different substances in its leaves, stem and roots that scientists can’t keep up. As a general rule, any chemical that is extracted from the plant’s leaves or stem can be called a “cannabinoid“. Still, even that term can’t do the multipurpose nature of the plant and its contents justice. In fact, it might be worth the read if you’re wondering how the different chemicals inside act. Understanding the therapeutic effects of each chemical is essential, and for that we’ve prepared a little reading list for your convenience.

Obviously, we won’t bore you with the jargon or the complexity of chemistry. We’ll keep things simple so if you’re new or an experienced marijuana user, you should find it easy to dip into this list. Also, this list isn’t a complete summary of the benefits of cannabis or anything. You can check out more benefits, like helping Multiple Sclerosis patients, or helping the elderly with chronic ailments on this site too. Without further ado, let’s start with the list.

Natural, uncooked cannabis

Nothing beats the efficacy of the mother nature. Raw cannabis has hundreds of chemicals that can be used in a multitude of ways. For example, you can smoke cannabis for a pleasurable high, or you can dissolve it in natural oils like olive oil and drink that too. Marijuana can be mixed into chocolate containing foods without changing their flavor much too. Pot brownies are the most common way people sneak cannabis into universities in the United States, because they’re easy to make and conceal.

Besides the direct uses, cannabis comes in many different varieties as well. There are two very commonly grown varieties, namely Cannabis sativa and Cannabis indica. Both have different concentrations of psychoactive agents, and hence give different highs. You can even get different experiences from cooking raw cannabis in many forms, but that does tend to convert some chemicals to different forms. All in all, nothing beats raw because of the various ways you can use it. The only downside to raw cannabis is that it is difficult to find and distribute across the United States.

Cannabidiol (CBD Oil)

Contrary to expectations, CBD Oil isn’t really an oil. It’s more like a mixture of different chemicals in different concentrations than what you’d find in normal, raw cannabis. It is usually a liquid at room temperature, which gives it the edge over raw cannabis in terms of versatility. You can mix it into your daily diet fairly easily.

However, in a lot of places, Cannabidiol or CBD Oil is mixed into gummy bears, chewable or other solid forms so it’s easier to transport and/or consume. It’s generally a little harder to come across than marijuana in the United States, but it’s benefits are worth going the extra mile. Users report that the high they get from CBD Oil is much more enjoyable. It can last up to two hours longer than the high they get from normal cannabis use.

Cannabis patches

If you want the pleasurable effects of cannabis but don’t want to buy paraphernalia, patches are the way to go. We all know how hard it is to carry a bong around, or how risky. They even come in variants with or without THC, so you can make sure you don’t get high in public. Plus, they’re discrete, and they don’t take too long to kick in. It’s definitely worth checking out.

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Better Keep your CBD Dosage in Check

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CBD dosage control

Cannabidiol demand is higher worldwide than it ever was. People are going for cannabis products in crowds. Keeping your CBD dosage in check becomes more important under these conditions. Let’s discuss different techniques and methods for this drill.

The United Kingdom legalized cannabis products in the country sometime back. People in the UK are using CBD products in much more amounts. Cannabidiol or CBD is one of the extracts of Cannabis.

While there are benefits of CBD products, excess of anything always proves bad. People should avoid any type of activity that could compromise their health.

Physicians prescribe that CBD products should be used in controlled amounts only. Overuse could prove harmful. Such as, excessive use of THC can actually deprive us of dopamine in long term.

Also Read: Why there are age restrictions on CBD products?

CBD is legal in the UK as it does not have more than 0.3 % THC. THC is the psychoactive component of the plant. It produces “high” sensations which grade against the law.

However, CBD products cannot be marketed for medical use. There is a myth revolving that marijuana products can serve as medicine for everything.

While these products can be helpful in many cases, they cannot substitute medicine. People should use them as pain relievers and relaxers but not as medicine.

Until now the only medical use proven of cannabis products is the treatment of epilepsy in children. CBD products are available over the counter in the UK. But they are not regarded as medicine.

People use CBD products for different kinds of pains. They are reported for use in anxiety, depression and insomnia. Different types of pains such as arthritis pain, joint pains etc. also become better with CBD usage.

There is no proven benefit of cannabidiol products against these problems. That’s the reason CBD dosage should be kept in check always.

 

How much CBD to intake?

This question is interesting and confusing at the same time. There is no doctor prescription for CBD products as little research exists in this area.

This depends upon many factors. Your body size is one of these factors. Your state of health is also important. A patient needs more dose than a healthy person.

Strength of the dosage is also an important consideration. Strong CBD products with high proportions of THC are not allowed in large amounts.

Strength of dosage varies. CBD oils can be labelled from 25 mg per dose to 100 mg per dose. You need to remain careful and act cautiously.

To relieve this confusion, some dispensaries are keeping a separate dispensary agent that prescribes amounts differing from person to person.

 

CBD Guru Dosage Calculator

Some entrepreneurs recognized this opportunity and made life easy for many people. CBD Guru Calculator is just one of such projects.

This software is easy to use and gives accurate requirements. Bodyweight is the prime parameter considered when prescribing through this calculator.

This calculator gives three different dosages as low, medium and high. They mainly differ depending upon what type of consumer is there. You can decide the best for yourself!

   Also Read: Hemp is a threat to Society, DEA rules

 

I think this calculator will ease the difficulty of many people. Now we can control our CBD dosage in a very efficient way. The methods applied are easy to use. Everyone can know the right amount of dosage.

Many governments around the world are looking into the legalizing option. However, not all of them will be able to regulate the usage of the product. We can only hope for the best for everyone!

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CBD Cream as a Pain Reliever?

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CBD as pain reliever

CBD cream now comes out as a pain reliever in addition to all other benefits. According to newfound researches, CBD products can help alleviate different body pains such as joint pain.

It is already a fact that Cannabidiol products help a lot in pain-related and mental health issues. It is very effective in many cases such as anxiety, depression and other neurological problems.

Now it is established that the drug helps relieve pains in ailments such as arthritis and migraines. When used for a long period of time, they can help against pain, inflammation and overall discomfort.

Also Read: What does CBD have in store for Horses?

In addition to these problems, CBD products can also ease muscle soreness, menopause and other pain-causing illnesses.

CBD should not be confused with THC, which is a “high” constituent of the drug. It creates a sense of euphoria where a person feels extravagantly relaxed and relieved. Everything becomes funnier and comfortable.

Marijuana is the product of THC in the cannabis family and not CBD. CBD in person does not have any psychoactive effects. It works by inhibiting the production of a compound resulting in pain sensation.

CBD also reduces inflammation which is also one of the major pain contributors. Due to these combined effects, it reduces pain to a great extent, and one feels relieved after consuming the drug.

Now we are ready to discuss the ways in which CBD can be applied for these benefits. One most common and easy way is to use it topically throughout the day. CBD cream is a very good method and is absorbed easily in the skin.

Apply the cream directly on pain source and break free from the pain. This will help greatly against muscle soreness and skin conditions.

CBD is a great pain reliever which is also useful against insomnia, irritability and anxiety. In the age of contamination, people always try to look for a better and more natural solution.

Also Read: Why Cannabis Industry Needs to Evolve to Face Climate Change?

CBD is the answer for all the calls regarding a natural solution for undesired illness and pain. However, it should not be confused with real-time effective drugs.

While CBD is a good reliever, certified and tested drugs should not be ignored. CBD can help relieve pain to a certain extent but after that, you need professional help.

While FDA is trying to analyze the drug as much as they can, they are also making efforts to regulate its use. CBD joins itself to the pain receptors in multiple pathways and reduces pain sensation.

However, some researchers still argue the authenticity of these assumptions. Ziva Cooper, a PHD. Researcher at UCLA says that this drug is very messy and has a lot of targets. Due to this reason, it is not possible to relate it to potential pain-relieving effects.

It is difficult to study the effects of CBD on the body due to these complications. Experimental observations suggest that individuals intaking CBD undergo pain relief. However, it is difficult to pinpoint whether the drug acts directly to reduce pain or is just a third party.

It is entirely possible that the CBD product you get from the market does not directly affect you. It can be a result of a by-product or a combination of other agents. At this point, it is difficult to make a statement.

The authenticity of CBD as a pain reliever is questionable. However, there is no harm in using the drug as of yet.

 

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