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Two Coronavirus Vaccines Prove Effective in Human Trials

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Recently, two coronavirus vaccines have proven effective in triggering an immune response in humans. According to the doctors, both drugs led to a similar response as the actual virus.

History

Coronavirus cases have been increasing ever since the virus’s outbreak in Wuhan, China last year. The novel virus belongs to the SARS family and was said to have spread from bats to humans. Soon after the outbreak, it became a global pandemic effecting a large number of countries across the globe.

The governments pushed majority of the nations into lockdown and implemented strict precautionary measures to control the spread of the disease. This adversely affected the world’s economy even causing the oil market to crash.

Various scientists and research groups have been actively working to find a treatment plan for the infection. Numerous attempts have also been made for developing a vaccine. Although, a number of potential candidates are in the human trial phases, FDA has not approved any of them yet. Researchers believe it will take a few more months for the vaccine to be available in the market.

Also read: Spain Orders Killing of 100,000 Minks After They Contract Coronavirus

Vaccine Trials

Recently two human trials testing different vaccines have produced a fruitful outcome. Both drugs were able to trigger an immune response similar to the actual virus in humans. The results showed that antibodies and white blood cell production in the body significantly increased to fight off the foreign bodies.

Source: Al-Jazeera

The human trial for the first vaccine was held in Britain. It involved over thousand adult subjects who were given a shot of the vaccine and the results were analyzed. The findings showed that the developed drug was able to induce a T white blood cell immune response. It also led to the production of strong antibodies in the body.

The second trial was held in China and involved around five hundred people. Like the trial in Britain, the Chinese study subjects were also given a dose of the vaccine. The results showed a powerful immune response in all of the volunteers.The findings from both studies were published in a science journal called The Lancet medical journal.

Future Implications of the Studies

Even if the vaccines do not prove effective in the more advanced phases, the research can prove to be an effective and important stepping stone for the ultimate development of the vaccine for the novel corona virus. Future research can work on, and improve the methods employed by the current studies to increase the probability of success in the vaccine development endeavors.

Also read: Moderna Produces a Safe and Effective Vaccine for Coronavirus

The lead authors of both studies stated that there were very few negative side effects observed in the subjects. They further added that the research is promising. However, more work needs to be done before the vaccine can be made available to the public. Particularly, the drugs need to be modified in order to reduce the intensity of their side effects in older people, who are more likely to die from the coronavirus infection.

Sarah Gilbert a co author of the study from the university of oxford said that if approved by the FDA, the vaccine can be easily produced on a large scale, given the procedure the development process follows.

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Can Cannabis Cause Complications in Surgery and Anesthesia Administration?

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anesthesia

There are undeniable health benefits of cannabis, and that’s what is moving the drug towards federal legalization. Some of the top health benefits include easing pain, and it also helps deal with insomnia. But the most important ones are related to the psychological help it can provide, including help in dealing with anxiety, mild to severe depression, and even PTSD. But is it beneficial for anesthesia administration and surgery too?

Cannabis or marijuana can help an individual find peace and enjoy their life to the fullest. However, if someone uses other drugs to manage a certain condition, cannabis can actually have some very negative effects. Cannabis and anesthesia are one such combination that can prove detrimental to health.

Anesthesia and Cannabis

Anesthesia before surgery helps your body relax into a state of self-induced sleep. This can become highly unreliable for cannabis users, and a cannabis user might ‘wake up’ before time. Cannabis users are advised to disclose all information about the usage of cannabis even if it is not in use in the near past, reported Leafy.

The anesthesia administering doctor will know how to manage the cannabis in your system and what dosage will be just fine for you. But to decide accurately, the doctor will need a complete disclosure. Anything less might make his calculations inaccurate, and you’ll be posing a risk to your own life.

An individual might be worried about disclosing cannabis use, particularly if it is against the laws of the state. A physician, nurse, and other healthcare support staff cannot disclose sensitive information under the oath of law.

The information may only be disclosed if it poses a threat to the life of someone and can only be disclosed to law enforcement agencies. The staff can also disclose the information in order to comply with a direct order from the court of law.

ALSO READ: Medical Cannabis Legal For School Students Or Not, In South Dakota

Cannabis directly affects cardiovascular and respiratory systems and increases the risks involved when an individual is under the influence of anesthesia.

The problem is still solvable only if the patient discloses everything to the doctor beforehand so that the doctor can take appropriate action. The social stigma attached to cannabis usage is now gone, and more than a dozen states have already declared it to be a legal drug.

Are THC and CBD Different under Anesthesia?

Cannabis is not just one drug; it has a number of active components, of which CBD is considered safe for medical uses, and THC is the Euphoric or recreational drug. The effects produced by both these components are quite different. Hence, it is important that the doctor knows the type of drug that you use so they can take appropriate action accordingly. The information should also contain information like frequency of use, periods of break, any effects, and the ways in which the drug is taken. Ingesting is usually many times more strong than smoke.

ALSO READ: Residents Against Opening of Medical Cannabis Dispensary in Bethlehem Township 

This difference is so important that anyone failing to disclose these things can pose a threat to their lives. This is because THC is assumed to increase heart rhythms and increase blood pressure. On the other hand, CBD slows down the heart rate and helps keep the blood pressure down. The differences don’t just stop there.

According to studies, THC stimulates appetite but can actually lead to slowed gastric motility with continued use. Moreover, THC and anesthesia elicit similar responses from the body. So, if the body has already developed some kind of tolerance to THC, the same tolerance will apply to anesthesia. This means that such an individual will need higher doses of anesthesia to exhibit the response needed.

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Cannabis

Now Get High with a New Cannabis Product In Ohio

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cannabis

As the cannabis industry is flourishing, new products are on the market, stores in Ohio have the latest hemp-containing product. Bills to legalize marijuana and decriminalize it are getting approval from lawmakers and officials at the state level. Competition in the marijuana business is also likely to increase as more investors are attracted to weed activities.

People who are already in the cannabis business in Ohio or other areas are working hard to expand their companies or organizations by retaining their position in the market. Increasing sales, introducing new items in the market, signing agreements, and other such activities, are means of improving business.

Delta 8 THC – The New Cannabis Product

Delta 8 THC is a new hemp item available at almost every store in Ohio. The product contains ingredients that cause consumers to become high. The components do not have any illegal ingredients. Some Delta 8 THC ingredients are capable of producing psychoactive effects. However, the formula does not go against the rules and regulations of the state.

Multiple types of stores, including convenience stores in Ohio, shops at gas stations, CBD stores, and online stores, provide Delta 8 THC in almost all parts of the state. Furthermore, there is no need for a prescription or official physician recommendation to purchase the new hemp product from the market. People without medical cannabis patient cards can also get Delta 8 THC.

ALSO READ: Here’s Everything You Need To Know About THC And CBD

Delta 8 THC contains less than 0.3% delta-9-tetrahydrocannabinol, this component is a psychoactive compound and increases brain activity. The percentage of THC in the new cannabis product is within the range specified by the Food and Drug Administration under the Controlled Substances Act and the 2018 Farm bill.

What Concerns Do People Have About The Product?

People are not sure whether the new cannabis product available everywhere in Ohio is legal or not. However, the legal authorities did clarify people’s doubts by confirming that the product is legally produced, manufactured, and sold.

Moreover, people are not overusing Delta 8 THC, and no issues or problems occur in people due to its consumption. Different consumers have different experiences of using the new cannabis products. Some users suggest that people shall not use high doses in the initial phase and shall be cautious while using Delta 8 THC product. The outcome of using it varies from person to person, but it is not hazardous to health.

ALSO READ: Discrepancies in Ohio’s Medical Marijuana Prices Reflect Barriers for Patients

People are hesitant to use Delta 8 THC that contains hemp. In Ohio, people are not objecting to its use. But federal and other state authorities have concerns about consuming the product formulated from the cannabis plant, reported news5cleveland.

According to Haren, there is a lot of confusion between what is legal and what is illegal in the cannabis field. The reason for this confusion is the difference or contraindication of federal and state laws regarding marijuana. Ohio and many other states have legalized and decriminalized marijuana involving activities. But on the federal level, such activities are still illegal.

Changing Cannabis Laws in Ohio and Other Areas

Lawmakers are suggesting various proposals and legislation. According to some lawmakers, instead of legalizing and decriminalizing cannabis in Ohio and other states, they can narrow the type of cannabis plant usage. Other changes include limiting possession of marijuana plants and product numbers.

However, different states have different limitations and regulations. Thus, it becomes difficult for people to determine which rule is applicable in which state. Delta 8 THC hemp product is accessible with ease in Ohio, but its legality in different states is questionable until the cannabis law formulation process is complete. Furthermore, every component of the new hemp product is going through an investigation process. Until the process is complete, there is no surety about its legality.

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A Study Says “Marijuana Can Treat Migraines”

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migraines

A neurological condition named migraine is common across the globe. Researchers are working to find new and more effective methods, including the use of marijuana to treat migraines. Physicians adopt various treatment strategies to treat the condition or reduce the pain individuals experience during migraines.

Migraine in Simple Words

A neurological condition in which people experience episodes of intense pain in the brain is called migraine. Apart from the pain, people also experience nausea, tingling, vomiting, numbness, and difficulty speaking. Some patients develop sensitivity issues to visual changes and slight light and sound alterations. As a result, such individuals get irritated when they are exposed to high-intensity light and sound.

Pain intensity varies, and it lasts for hours or days continuously. Types of pain can be different; some patients experience throbbing or pulsating pain, others experience radiating pain, and it usually occurs on one side of the brain.

ALSO READ: CBD Cream as a Pain Reliever?

There are various types of migraines, and the percentage of people affected by each type also varies. People may suffer from acute or chronic migraines. The neurological condition can develop in any individual irrespective of age. The cause of the condition varies from person to person. Family history, genetics, stress, and other factors contribute to the development of migraines in people. Some people begin to use marijuana on their own to treat migraines.

People with migraines develop depression and get agitated on smaller or smaller changes. The pain experienced during migraines causes problems in sensations, movement, vision, and speech. Patients with migraines with different symptoms use marijuana, THC, or CBD-containing substances to cure their migraines.

Procedure Used to Conduct the Study

Physicians do not recommend the use of CBD or THC products or products containing both CBD and THC for migraine treatment. They lack evidence of cannabis effectiveness in treating neurological conditions.

The research investigators intend to enroll 90 participants for fulfilling the purpose of the study, reports Kpbs. People of age limits between 21-65 who have migraines each month and do not use opium or are not habitual drug users can apply for participation. Participants that fulfill qualification criteria can become part of the research investigation.

These participants will be divided into four groups, and each group will receive four different treatments. The first group will receive CBD-based treatment, the second group will get THC-based treatment, and the third will get a combination of CBD and THC for treatment. However, the fourth group will only receive a placebo.

Administration of marijuana constituents containing products occurs through a vaporizer. According to Dr. Shuster, people with migraine symptoms, including nausea, vomiting, or gastrointestinal discomfort, can get better by consuming vaporized cannabis.

ALSO READ: Cannabis Inhaler, a new way of consuming cannabis

Monitoring the effectiveness of THC, CBD, and marijuana-containing compounds in treating patients with migraines occurs. Observing the effectiveness of the compound and further studies can enable researchers in designing and determining the dosage regimen of marijuana.

What Researchers Found Through their Study

US San Diego Health took the initiative to conduct a study to determine the effectiveness of marijuana in treating acute migraines. The researchers found that despite multiple FDA-approved treatment methods available in the market to cure migraines, people use more marijuana, CBD, or THC-containing products to treat their migraines.

Nathaniel Schuster is an investigator at UCSD Center for Medicinal Cannabis Research. Schuster works at UCSD Health as a headache neurologist and pain management specialist. According to Nathaniel Schuster, patients have been self-treating migraines and using marijuana-containing substances on their own.

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