This year in October, Canada will officially legalize the use of cannabis flower. By doing so, they would be able to produce and manufacture a wide range of products and make use of their advantages.
The cannabis flower helps in maintaining health and also quickens the healing process. Its legalization will urge the investors as well as provide opportunity to them to invest more in this venture. It will also furnish more opportunities to the manufacturing industries of the cannabis products. These companies would manufacture CBD edibles and dried sales of these flowers.
Hexo Corporation is a major cannabis flower products manufacturer. This company had a major drop down in shares by at least 50%. This gave investors a chance to invest in the lower priced shares. Hexo’s competitor Horizons marijuana life sciences had a fall of shares by 39.1%.
The cannabis manufacturing companies were restricted due to the supply issues. Due to this reason, fewer products were manufactured which ultimately led to a drop in sales and shares.
Hexo Corp. may be down at the moment but they are a strong company and they can become a leader in the sales of the cannabis flower. They have an agreement with Molson Coors Brewing to produce CBD infused products and beverages. Hexo Corp. owns about 600,000 square feet land to grow and process CBD products. They expect to have a sales growth from $59.7 million in 2019 to almost $400 million in 2020.
Organigram Holdings sales fell by 30% in August. Canada’s health department has been extremely slow in approving sales license for the company. The Organigram Holdings postponed the launch of CBD derivative products till December rather than the October.
Organigram is different from others for couple of reasons. While most manufacturers are located in Ontario or British Colombia, Organigram is located in the New Brunswick. At the moment, Organigram is the only cannabis company to have supply agreements with all the provinces in the country.
Unlike the two companies mentioned above, MediPharm labs is an extractor and provider rather than a cannabis producer. An extraction-based provider like MediPharm has been a self-relying and convenient producer as told by the experts.
If an investor has to choose between many extractor stocks, he/she would definitely pick MediPharm for a couple of reasons.
One reason is that MediPharm is already gaining good profits margins. Medipharm’s sales may not be as expected by an investor but they seem quite impressive when you consider that it had very few sales in the last year.
MediPharm has also gotten extraction contracts with big companies such as Canopy Growth and Cronos Group. These agreements will cost millions of dollars and would also assist the firm to flourish over the next few years. As CBD derivative products are offering a greater profit as compared to dried flowers, much more firms are initiating the services of extraction like medipharm.
With the legalization 2.0 of cannabis, medipharm may have a hand in many more extraction agreements and projects with massive profit margins.
Long Term Use of Cannabis Could Affect Your Social Behavior, Here’s Why
While there’s no denying the fact that cannabis has tons of medical benefits, extended exposure to it could have serious social behavioral repercussions.
In a nutshell, long term use of cannabis affects the ability of astrocytes to manufacture food for neurons from glucose. This reduced food production compromises on the neural function, which appears to have adverse effects on the person’s behavior.
The way long term cannabis use alters behavior appears to have a direct link with the cannabinoid function. While it is mostly observation and researchers know of no concrete mechanism yet, cannabis consumption could lead to reduced social interactions and withdrawal.
A deeper understanding of the cannabinoid receptors could prove fruitful in determining the relationship between cannabis and social behavior.
The role of cannabinoids
The role cannabinoids play is much more important than ever since some of these receptors are also present on the mitochondrial membrane. ‘Mitochondrion is the powerhouse of the cell’, is a statement almost everyone is well familiar with. If something were to happen to the mitochondria inside the cells, it could very well reflect on the person’s behavior.
Mitochondria metabolize glucose into lactate, which neurons use as food. The main psychoactive compound in cannabis is THC. A better understanding of the relationship between the two could open doors to new possibilities.
Observations in mice reveal that if astrocytes are exposed to THC for an extended period of time, the cannabinoid receptors present in them start a chain of reactions that in turn lead to glucose metabolism dysfunction.
Therefore, there’s less available ‘food’ for astrocytes. This is like operating some heavy machinery with dry cells from a TV remote. Observations made suggest that this lack of ‘food’ has a direct impact on the subject’s behavior.
Moreover, in extreme cases, exposure to THC hampered social interactions for up to 24 hours.
While uncontrolled use of cannabis could be dangerous, controlled use with appropriate observations could very well be used to deal with some behavioral problems more easily and effectively.
The debate over therapeutic cannabis is yet again a hot topic. A better understanding of cannabis’ effects on the human body could help in finding the optimal solution.
However, for now, a simple rule to keep in mind, excess of everything is bad.
Pennsylvania: Lt. Gov. Fetterman Urges Cannabis Legalization
Lt. Gov. John Fetterman urges Cannabis Legalization to reduce the impact of the budget deficit. Due to the COVID-19 pandemic, the economy has suffered a lot. Due to the economic setback, the state faces a budget shortfall of $3.2 billion.
Fetterman tweeted to support the legalization of recreational marijuana. He says that legalization of marijuana will open new avenues to generate tax revenue. According to Fetterman, the legalization of marijuana could generate half of this COVID-19 deficit. It will also be helpful in reforming the state prison system.
Recently, Lt. Gov. Fetterman took to Twitter in support of cannabis legalization.
If only there was a widely-consumed unregulated cash crop, wholly confined to the black market, that could generate billions of dollars + 1000’s of jobs + help PA farmers. https://t.co/oIfEeUb8sm
— John Fetterman (@JohnFetterman) July 2, 2020
Catering For Budget Deficit
In an economy greatly hit by the global pandemic, the legalization of recreational cannabis will help providing thousands of jobs to the unemployed.
Majority people of Pennsylvania support the legalization. Fetterman is of the viewpoint that cannabis in Pennsylvania could bring up to 500 million dollars into the state’s coffers which is why he urges Cannabis Legalization.
I don’t know who needs to hear this jk I know who- but earnestly reforming our state prison system + legalization of marijuana could generate half of this COVID-19 deficit.
It would, however, could have other unintended consequences like justice and personal freedom.
— John Fetterman (@JohnFetterman) July 2, 2020
Pennsylvania has a big marijuana market. Its legalization will allow Pennsylvania to stand on its own feet.
Some other politicians, however, disagree with the notion of legalization. They think that instead of adding new taxes, they should try to control the spending. The bill to legalize the adult use of Marijuana is in the committee. However, nothing can be said about the legalization with certainty.
However, According to State Sen. Stefano, his committee is reviewing new research. He told KDKA’s Meghan Schiller that the biggest hurdle is that there is no measurement technique for determining THC concentration in the human body. He said he’s hesitant to move forward, until there’s a way to determine the amount of intoxication.
The State Senator said that the bill was in his committee and he didn’t have plans to bring it up anytime soon. There is still room for a lot of research to be done. The decision to legalize adult-use marijuana isn’t a very wise decision without taking all the factors into account.
However, it’s research business owner Posteraro sees this as an opportunity. He hopes that it doesn’t take too much time to legalize it, because opportunities like these seldom present themselves.
Whether or not Cannabis should be legalized still remains open to debate, but there is no denying could help the nation face a huge financial deficit.
Cannabis Rendered Helpful in Saving Lives of COVID-19 Patients
Recent Researches revealed how Cannabis plant can help in saving lives of COVID-19 patients. The active components found in Cannabis Plant make it seem as a possible treatment for coronavirus infections.
Anti-Inflammatory Properties of Cannabis
The University of Nebraska and the Texas Biomedical Research Institute are conducting further researches to study the utility of CBD to check its utility in treating inflammation of lungs caused by coronavirus. The anti-inflammatory properties of Cannabis can be especially valuable in improving issues related to behaviour, immunity and brain.
Researchers explained that the infection is related to a cytokine superstorm, that causes symptoms like cough, fever and muscle pain. The increased inflammation can even cause pneumonia and breathing difficulties. Breathing difficulties are the number one cause of deaths due to COVID-19.
Reduction in the Amount of Cytokines
Previously, researches conducted on CBD show that it can bring down the level of several cytokines, that cause inflammation, including IL-6. It also helps in controlling interleukin (IL)-2, interferon gamma, IL-1α and β, inducible protein-10, macrophage inflammatory protein-1α, monocyte chemoattractant protein-1 and tumor necrosis factor-α. Excess of these leads to severe COVID-19 conditions. Moreover, CBD also increases the interferons production. Interferon is a protein that prevents viruse replication and activates immune cells.
CBD’s anti-inflammatory properties have worked wonders for asthma patients by reducing the production of pro-inflammatory cytokine production. CBD also reduces pulmonary fibrosis. This condition causes scarring, thickening and damage to the lung tissue, along with making breathing considerably more painful. COVID-19 actually leaves patients with pulmonary fibrosis. This is the major reason why Cannabis can greatly help COVID-19 patients.
An insight into how COVID-19 works
Much like other respiratory pathogens, COVID-19 is also spread through respiratory droplets. However, it also has potential for contact and aerosol spread.
Coronavirus makes it way into the human body through receptor-mediation. This is done through angiotensin-converting enzyme II (ACE2). ACE2 is present in lung tissue, oral and nasal mucosa, gastrointestinal tract, kidneys, and testes.
This information opens door to a new way of hindering the spread of coronavirus. Modulation of ACE2 could prove fruitful in this regard.
A special strain of cannabis can render this function. Through ACE2 modulation it could block the virus’ entry into the human body. Nipping the evil in the bud.
Basically, ACE2 acts like doorways to the virus. The main idea is to temporarily alter the extent of ACE2 gene expression. Therefore, it could very well make the human body a no entry zone for the virus. The same strain could also be used to stop the virus’ propagation if it has made its way into a person’s body.
This is where Cannabis sativa comes into play. Plants with high CBD content have been proposed as a way to modulate the ACE2 gene expression in target tissues.
At this point in time, it is more of a theory than a confirmed fact. However, it sure opens a new avenue with promising prospects. If it proves successful, the next step would be to start manufacture that particular strain into a medication.
It sure looks like CBD properties of cannabis can prove fruitful in the treatment and prevention of coronavirus. However, further research will prove whether it is the case or not.
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