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Coronavirus might end with a newly proposed treatment

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A recent trial for a possible treatment for the coronavirus infection has hinted towards hopeful results with DNA vaccine.
Since the coronavirus outbreak in November 2019, the number of effected patients has continuously been increasing. Numerous scientists and research groups are working to develop an effective vaccine and find a possible treatment. However, until now there has been no fruitful outcome. Some speculate that a vaccine would be ready in a few months. However, other reports state that the teams are not even close to developing a cure.
 
A recent vaccine trial has shown some progress in finding a treatment. It has proposed the use of DNA vaccines as a possible solution to end this crisis altogether.
 
Currently, a large number of doctors are employing convalescent plasma therapy. Recovered coronavirus patients are plasma donors. Doctors then inject this plasma in critical patients to improve their immunity. Since it contains appropriate antibodies to ward of the disease, the process has shown some positive results.
 
 
However, it is to note that the technique is not very efficient. Finding a matching blood group can sometimes pose a serious problem. Therefore, the search for the universal solution is still going on.

Clinical Trial

Published in the journal, Science, on 20th May, a study by students from Harvard Medical School in Boston, has shown positive results from DNA vaccine testing on monkeys.
 
By injecting genetically modified plasmids into the blood stream, DNA vaccine can treat infections. The plasmids contain an antigen sequence that trigger an immune response. This allows for the body to make appropriate antibodies.
 
In the trial, the research team produced six distinct DNA plasmids – or DNA vaccines, with an antigen – a spike protein, of the SARS-CoV-2. The theory behind the process was to trigger an immune response and study the antibodies produced as a result.
 
Researchers injected different variations of the plasmids in 35 monkeys – rhesus macaques. They were further infected with coronavirus o see which iteration produced the optimal results. Results showed that one of the six – the one with the complete encoding of the spike protein – was significantly more effective than the rest.
 
Numerous blood tests showed that despite the symptoms, that matched those of the coronavirus, the monkeys did develop numerous new antibodies that were not present before. When studied in detail, the immune response proved to be similar to that of the human coronavirus patients who have recovered.
 
 
The study also showed that unvaccinated monkeys had more virus molecules in their system as compared to the vaccinated ones – hinting towards a more active immune response in the latter.

Conclusion

Researchers have not carried out the trail on humans; however, they believe that it can prove to be a vital step towards finding a cure. Using DNA vaccines that encode the full sequence of the spike protein might trigger a similar response in the human counterparts as well.
 
However, this was just a basic level trial. It requires further research to see if the results were not accidental. Moreover, durability of the vaccine and effectiveness of the antibodies is still not confirmed and hence, needs more testing.
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Cannabis

Cannabis Industry, Celiac Disease, And Processed Flour

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Cannabis And Flour industry

The cannabis industry shall learn from the errors of the flour and cheese industry. Use of certain products, including bleached-flour and consumption of mass gluten, causes multiple diseases, including celiac disease. Due to this reason, many countries around the world including the U.K. and China restrict the use of mass-gluten in the production of flour and cheese.

However, the North American Flour Industry uses two restricted bleaching agents, namely calcium peroxide and benzoyl. Moreover, they use these bleaching agents in the formulation of flour. The possibly damaging point is that these bleaching agents lead to the development of autoimmune diseases and celiac. 

The cannabis industry must solve and prepare beforehand for various problems to continue evolving. Moreover, the marijuana industry has been under suppression for a longer duration. Thus, it must take every step considering the consequences and make efforts to evolve. 

ALSO READ: Colorado In Need Of Regulations To Restrict Marijuana Concentrates To Keep Teens Safe

Vape pen formulation also causes oxidation issues similar to the flour-industry. So, the cannabis industry needs to modify formulation formulas and techniques to produce products that do not lead to diseases. Moreover, there are chances that these diseases can lead individuals to death. Thus, there is also an immediate need to cut off ingredients from processed foods, flour, and other products that can cause cancer or other autoimmune diseases.  

What Is Celiac Disease?

Celiac disease is an autoimmune disease and is a genetic disease. People with the genetic-disease may or may not have symptoms. However, people with asymptomatic celiac disease can develop symptoms later in life. 

Furthermore, the risk of developing celiac disease increases due to various factors, including excessive gluten consumption and eating a lot of processed foods. The main ingredient causing autoimmune-disease is benzoyl peroxide, as it affects flesh and gut bacteria. 

Moreover, benzyl peroxide irritates the skin, causes an antibiotic response, and generates free radicles. Overall, it damages the body and causes the development of autoimmune diseases and cancer. The cannabis vape pens also change color after some time, and oxidation of its agents causes an alteration in its formula leading to pathological conditions. 

Excessive Gluten Consumption And Cannabis

Cannabis industrialists must not use ingredients that can damage the body organs or cause any disease. Moreover, the industry shall avoid using ingredients that it uses to prevent the decolorization of vape pens. Moreover, such chemicals are capable of increasing the risk of autoimmune diseases like celiac disease. 

Individuals with celiac disease have high amounts of enzyme elastase. Gluten breakdown occurs in the presence of enzyme elastase. After breaking, it converts to an amino acid and is considered by the body as toxins. The body begins to fight itself, leading to the initiation of autoimmune diseases like celiac disease. 

Excessive gluten consumption results in a large amount of amino acid production. Moreover, the body considers the amino acid as a toxin and starts to fight the cells containing it, leading the body to fight its cells. Furthermore, mass gluten consumption causes microbiome disruption and strips away the microbiome barrier. 

Benzyl Peroxide And Other Food Alterations 

In addition to gluten, benzoyl peroxide and other such agents in processed flour and cannabis products can have a peeling impact. The bleaching agents erode intestinal-lining, leading to breakage of the wall and damaging the digestive and immune system. 

ALSO READ: U.S. States Most Likely To Legalize Cannabis Recreational Use

Food is changing genetically, and alterations in the soil are also occurring at a faster rate. Moreover, genetic alterations in the plant seeds cause other beneficial effects, but few are life-threatening. 

Furthermore, cannabis cultivation and production need new modified methods for maintaining a variety of marijuana. Over the coming years, how the food industry and crop cultivation changes for the better are yet unclear. However, researchers need to formulate better techniques for future healthy varieties of food and crops. 

 

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Cannabis

Mental Health Issues Marijuana Use Rises In Teenagers Arising Concerns

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Marijuana use rise in teens

The research finds that after legalization, the use of marijuana may increase in youngsters-extremely. Some government officials and lawmakers oppose the legalization of cannabis and favor banning and suppressing cannabis use. Such individuals highlight that the use of stronger cannabis drugs affects teenagers. Moreover, it affects their brain functioning. 

Such reasoning is an old social problem that drug addiction is spoiling the new generation of kids. There remains a gap or a gulf of the-gap in the character building of kids. A moral fault or weakness remains forever in their character building.

Lawmakers and the government have enabled the cannabis industry to overcome some of its problems and difficulties. However, certain matters still need to be solved. Decisions occur according to a new bill legalizing cannabis regarding cases and suits on high nicotine products in the court of law. 

ALSO READ: Cannabis Patient Employment Rights In Pennsylvania 

Authorities are considering the possible results of the new policies on marijuana. The cannabis industry is still facing weaknesses and faults in its policies controlling the cannabis situation. The marijuana industry also plans of introducing rules and regulations to solve the problems.

Survey Reports Highlight Increase Trends Of Marijuana In Teenagers

According to last week’s study, teenagers of grades 7, 9, and 11 are more likely to use cannabis upon approval of legalization and decriminalization. It can make youth addicted to cannabis. 

The report in the Journal of Studies on Alcohol and Drugs highlights that in 2016 when California legalizes marijuana, younger individuals of grade 9 and 11 use 23% more cannabis at the end of the year. 

The 2016 survey study regarding drug use was the first research study of its kind. Previously, cannabis use in teenagers did increase. However, the rise in the number of teenagers involved in drugs has risen remarkably. Moreover, it is likely to rise further. Thus, the situation is increasing concerns. Another research study in Colorado elaborates on the rise in the number of adults involved in cannabis activity from 2017 to 2019. 

Concerns Regarding Cannabis Abuse

According to the National Institute on Drug Abuse, cannabis excessive use and early on-set of use cause irreversible damage to the brain. Furthermore, it also increases the risk of drug abuse, addiction, and schizophrenia

The U.S. Cannabis Council is working on the legalization and decriminalization of cannabis. Moreover, the council came into formulation this month to discuss and manage issues regarding cannabis. 

According to Steven Hawkins, the matter of teen use of cannabis is a critical issue for the public. Moreover, he added that even if the bill for legalization and decriminalization of cannabis passes, still, efforts are to be taken for discouraging underage use. 

ALSO READ: Congress Members Demand Biden To Declare Mass Forgiveness Before Cannabis Legalization

High Potency Users 

The use of high-potency psychotic drugs is dangerous for the health of individuals in the longer run. New cannabis products on the market contain a high dose of THC. Authorities have concerns that the use of high THC marijuana products could potentially increase the risk of addiction. 

Moreover, according to a 2019 study, the use of high potency cannabis products daily increases the risk of having a psychotic disorder as compared to those who avoid marijuana products. Individuals who begin using cannabis high-potency products at the age of 15 have a higher risk of developing a psychotic disorder. 

In Colorado, a proposal suggests banning cannabis products containing more than 15% THC. Moreover, only patients will get approval to buy cannabis products of high-potency containing more than 15% THC. However, the U.S. Cannabis Council does not want anything like that to happen. According to Hawkins, the manufacturing of cannabis products of high demand in public shall occur.

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Cannabis Intake Can Help With Controlling Blood Pressure

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Cannabis Intake Can Help With Controlling Blood Pressure

Medical cannabis usage is on the rise as more and more states legalize it. Cannabis provides some undeniable medical advantages and among them is the miracle of lowering blood pressure. According to a new study, medical cannabis may have the potential to keep blood pressure in check.

The research is part of a study at Ben-Gurion University of the Negev (BGU). The University has affiliations with the Soroka University Medical Center. The study got the nod from the European Journal of Internal Medicine and is part of the current volume.

The participants in the study were adults ages 60 and above. The aim of the study was to focus on the effect of cannabis on blood pressure, pulse rate, and other metabolic processes. This is particularly important as more and more people are resorting towards the recreational drug. If there are benefits of its use, they should definitely get the spotlight. As an increasing number of above 60 people use medical cannabis the effects warrant a study.

Decreased Blood Pressure Due To Cannabis Use?

The participants are all under evaluation and the study took 24-hour ambulatory blood pressure monitoring. Alongside the monitoring, ECG, blood tests and body measurements were also taken. This was done before the study took off and after three months of cannabis therapy.

ALSO READ: Marijuana Legalization And Decriminalization Bills Delayed By Murphy 

The study is a first of its kind and was shown a lot of promise. There was a significant drop in the average blood pressure levels . The lowest point of the blood pressure was about three hours after taking cannabis. This intake could be in any form. Also, the fall in blood pressure is consistent both in the daytime and nighttime.

The BGU research team also thinks that the relief from pain that participants go through is also due to the cannabis. In actual, they believe it is a combination of both, cannabis intake and reducing blood pressure.

The BGU facility of Health Sciences is one of the best medical facilities in Israel. The BGU Soroka Cannabis Clinical Research Institute aims to link the actual physiological effects of cannabis to the frequency and amount of use.

A Study In the Right Direction?

This aspect of cannabis use is unheard of before but is definitely worth the attention. The study aims to provide clinical research to support the medicinal use of cannabis. Perhaps the most intriguing thing about the effects is the fact that all forms of cannabis, whether oral, oil extract or taken in smoking form produce the same effect. The most significant change in the blood pressure is at night. This piece of information needs some more research to replace bedtime hypertension control drugs. Although the research available on the use of cannabis is not much, but it is a step in the right direction.

ALSO READ: Cannabis Industry Updates Of This Week By 420 Investor

The absence of relevant literature is largely due to the illegality of cannabis in the past. But, as mentioned, it is a thing of the past and the future is ready to embrace cannabis and its medicinal wonders.

The chief executive officer of American Associates at Ben Gurion University, Negev also thinks that it is a little early for forming conclusive opinions. The research is indeed a first but he thinks that more effort needs to be focused on the subject. Once enough clinical evidence is available to support the claim, we can head into the future with hopes of an all-natural deterrent to counter silent killers like hypertension.

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