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Trial shows a possible cure for a rare blood cancer type

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A recent clinical trial has shown positive results for a treatment plan for a rare form of lymphoma blood cancer.

What is Lymphoma?

Found in humans, Lymphoma is one of the most common types of blood cancer. Developing from a group of lymphocytes, the cancerous growth occurs around the lymph nodes, causing them to enlarge. However, a rare subtype of the cancer – Intravascular large B-cell lymphoma (IVLBCL) is sometimes hard to diagnose. Hence, leading to a relatively high mortality rate.

IVLBCL is a form of ‘extranodal malignant non-Hodgkin lymphoma (NHL)’, that causes the lymphoma cells to grow within the capillaries and small arteries or veins. Since the growth takes place inside the blood vessels, the cancer is extremely difficult to diagnose. Particularly during its early stages of developement. Further, the presentation of symptoms is generally non-specific, which makes the diagnosis even more challenging.

As of date, there is no effective treatment for IVLBCL. Since, it mostly develops in senior citizens, the patients are not able to withstand the side effects of extensive chemotherapy. Hence, majority of the patients end up denying the treatment altogether. There is an elevated risk of developing permanent “central nervous system” disorders, even after the treatment.

Also read: New Mexico – Governor in Favor of Legalization of Recreational Cannabis

Numerous studies have focused on finding a possible treatment for the disease, however, nothing significant has been developed so far.

Clinical Trial

A group of researchers from Mie University and NogoyaUniversity, Japan, recently tried to test a new treatment plan that would effectively target the cancer and also minimize the side effects. The study analyzed the patients’ data and concluded that those who underwent chemotherapy combined with “rituximab” drug, showed promising improvements in their overall condition.

However, it still does not prevent or reduce the secondary side effects on the central nervous system. According to Dr. Kazuyuki Shimada, “We considered that rituximab-containing chemotherapies combined with treatment for the secondary CNS problems could lead to further improvement in the clinical outcome.”

The trial consisted of 38 patients between the ages of 20 and 79. They were diagnosed with the Intravascular large B-cell lymphoma but were not showing signs of any central nervous system disorders. The subjects were monitored over several years and the finding were published in a scientific paper, The Lancet Oncology.

Results

The treatment procedure showed some positive results. Out of the total patients, 76% reached the two year survival goal without the progression of disease, whereas 92% reached the overall survival goal. The treatment significantly reduced the overall side effects and only 3% of the patients showed CNS damage. The team also reported that there were very few serious complications that occurred during the trial, especially in comparison to the average number of complications with a standard treatment.

Also read: Ontario Begins Virtual Inspections for Cannabis Stores During Lockdown

Dr. Shimada summarized the findings, saying, “It appears that the proposed treatment protocol might be effective in patients without apparent central nervous system involvement at the time of diagnosis.”

However, further research needs to be done to come to any definitive conclusion. Especially, since the trail group was very small, and the results might be purely coincidental. Despite that, the treatment can stills be employed in clinical practices, since it does not use any ‘novel’ drugs – i.e. all the compounds used are already being used for IVLBCL’s treatment across the globe.

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Cannabis

Variety Of Marijuana Strains Yield Different Health Impacts 

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Marijuana Strains

Marijuana is a plant that has many beneficial medical uses. Moreover, researchers are discovering more and more about the effectiveness of cannabis in treating various psychological and pathological conditions. The plant has been gaining popularity for its health effects. 

Marijuana is effective in reducing pain and anxiety. It is also applicable for elevating the quality of sleep, and recently it is famous for being an aphrodisiac. The impact of various strains of cannabis is different.

Marijuana strains are classified as indica, Sativa, and hybrid. However, the classification is considered controversial. Moreover, each variant-strain of cannabis generates a specific effect. But personal preferences also determine what individuals will use and how it will affect them. 

ALSO READ: Cannabis Strains Perfect For Parents During Back-To-School Season

Are There Any Marijuana Genital-specific Strains?

There is no evidence of the existence of marijuana strains that can result in genital-specific arousal. However, cannabis is usable for treating and helping to ease certain penis-specific situations. Moreover, individuals with anxiety associated with erectile dysfunction can take the anxiety-reducing strain of cannabis.

According to a 2017 study, marijuana use has a positive link with sexual frequency. Moreover, according to some studies, cannabis users have sex more often. Furthermore, there is a possibility that cannabis leads to increased libido levels. 

However, some research studies disagree with cannabis having a positive association with sex. According to a 2011 literature review, frequent marijuana use can cause erectile dysfunction. There is another study of 2010 that links daily use of weed to the inability to achieve orgasm. 

Thus, further research is essential to understand the true-effect of marijuana on sexual health. However, without sufficient evidence, people are still using cannabis to enjoy sex, boost their libido, and deal with other undesirable symptoms like pain or depression.

Various strains of cannabis generate different effects on different individuals. So far, there is no guarantee of which cannabis-strain will be beneficial for your sexual health. Moreover, it is wiser and safer to use marijuana strains with the recommendation of doctors and under their supervision. 

Strains For Arousal 

The two strains most frequently used for enhancing libido are Sativa-dominant hybrid (Sweeties) and hybrid (OG Kush). Sweeties contain 22 percent THC, while OG Kush contains 18 percent THC. 

Sweeties produce euphoria and are usually used for relieving stress, anxiety, and low libido. OG Kush has a reputation for generating happy feelings. However, the usage of OG Kush makes consumers a little sleepy. Thus, consuming it in small doses is safe and effective.

Treating Depression With Cannabis Strains

Depression can lead to multiple conditions including erectile dysfunction, lethargy, fatigue, and low sex drive. Many individuals use Strawberry Diesel and Jillybean to treat depression. Both are hybrid marijuana strains.

Jillybean and Strawberry Diesel strains contain zero CBD, but both have 16 percent THC each. Moreover, jellybean is energizing, produces euphoria, is a mood elevator, and perfect for combating depression. However, Strawberry Diesel does have a euphoric, mood uplifting effect, but it is not too energizing. Moreover, it is not sleep-inducing and thus is useable during day time.

ALSO READ: Cannabis Greenhouse Effect – Areas With More Emission

Getting Rid Of Anxiety And Stress With Aid Of Marijuana Strains

Stress and anxiety are both common libido killers. Moreover, stressed individuals are unable to enjoy and have fun. Furthermore, stress can lead individuals to exhaustion, brain fog, and irritability. It also decreases the potential for sexual pleasure. However, the use of marijuana strains will enable the consumer to reduce stress levels and soothe anxiety. 

Sherbet and Locktite are hybrid strains of marijuana containing 18 percent THC capable of producing euphoria. For arousal, individuals use Locktite, and Sherbet is effective for erogenous play. 

Moreover, if individuals desire to use more energetic strains, they can use Durban Poison and Harlequin. Both have Sativa-strain of marijuana, but Durban Poison contains 17% THC, and Harlequin contains 5% THC.

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Cannabis

Cannabis Greenhouse Effect – Areas With More Emission

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Cannabis Indoor cultivation

Cannabis can cause climate change that can affect the environment and life of human beings, reports The Conversation. The extent to which marijuana contributes to environmental alterations depends upon its cultivation technique and location.

The marijuana industry is expanding, and lawmakers are working on legalizing its cultivation, possession, and other activities across the United States. The cultivation of cannabis can occur indoor and outdoor. However, the effects of cultivating marijuana indoors are different from its cultivation in open outdoor fields.

According to a recent study, cultivating cannabis indoors results in the production of large amounts of greenhouse gasses. Moreover, the impact of these gasses depends upon the location where cannabis indoor cultivation occurs.

ALSO READ: Texas A&M Freshman Desires To Expand Cannabis Medical Use

Energy For Cannabis Indoor Cultivation

Cultivating cannabis indoors requires a controlled environment and source of energy, light, water, and other suitable conditions. A lot of electricity is utilized in producing sufficient light for the cultivation and growth of marijuana indoors. 

Moreover, cannabis cultivation at an optimal growth rate requires a lot of energy. Energy is essential for producing a comfortable growing environment for the marijuana plant. Furthermore, air conditioners and heaters are essentially required to keep the temperatures within a suitable range. 

The growth and cultivation of plants require the presence of a certain percentage of carbon dioxide. Thus, cannabis producers pump carbon dioxide into the indoor marijuana cultivating unit. However, apart from the beneficial effect in the growth of cannabis, carbon dioxide contributes to 11% to 25% of greenhouse gas emissions in facilities. 

Producers require a proper ventilation system that allows clean, fresh air at a suitable temperature and humidity levels to enter the indoor cultivating unit of cannabis. Availability of air is essential for growth but cleaning it and correcting its temperature and humidity is possible with an energy-intensive process.

Intensive energy and other production requirements increase greenhouse gas emissions. Moreover, in some regions, the emission of greenhouse gasses is higher than in other localities. 

Areas With More And Less Greenhouse Gas Emissions 

Regions with milder climates require less heating and air conditioning. Moreover, their electric grids use more clean energy. As a result, greenhouse gas emissions in such regions are less than in other areas.

According to Department of Energy, Environmental Protection Agency, and industry data, growing pot cannabis indoors results in greater emissions of greenhouse gasses in the Mountain West, Midwest, Alaska, and Hawaii in comparison with Pacific and Atlantic coasts. 

Moreover, cannabis in southern California has the lowest emissions, and eastern Oahu in Hawaii has the highest greenhouse gas emission. Greenhouse gas emissions in Southern California are at 143 pounds of carbon dioxide, equivalent per ounce of dried marijuana. However, 324 pounds of carbon dioxide equivalent per ounce emission occurs at Oahu in Hawaii. Moreover, this emission is equivalent to burning 16 gallons of gasoline

Greenhouse Emissions From Cannabis And Its Impact

The emission rate affects the environment, but authorities, cultivators, and industrialists do not consider the environmental impact. There is an urgent need to take measures regarding the greenhouse effect of cannabis cultivation to control the possibly worse situation. 

ALSO READ: Denver’s Cannabis Ordinance Will Jeopardize Hard Earned Public Health And Safety

There are old warehouses that use outdated equipment that emit more greenhouse gasses as they are less energy efficient. Furthermore, there is a need for developing new better techniques for growing high-quality cannabis with energy-efficient methods. 

Unknown variations in the cultivation process and growing methods make it hard to design effective policies that can enable producers to limit the emission of greenhouse gasses. Moreover, one serving of THC, roughly 10mg dried-flower, yields more greenhouse gasses emission than a serving of beer, wine, spirits, coffee, cigarettes.

Furthermore, it is better to cultivate and grow cannabis outdoors in open fields with a suitable environment as it will lower the emission of greenhouse gasses. 

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Texas A&M Freshman Desires To Expand Cannabis Medical Use

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Cannabis Medical use expansion

Cannabis is an illicit drug that is applicable for treating certain medical conditions. Moreover, marijuana is effective in treating psychological disorders but due to its dependency nature and ability to cause addiction, its use is restricted. 

The cannabis industry continues to explore new products, lines of administration, and much more. Furthermore, researchers are working on finding possibilities to expand the medical use of cannabis. Research and development projects continue to work and explore marijuana deeply. 

Julia Patterson is a Texas A&M freshman and has a political science major. She is the first to become one of the youngest registered lobbyists in Texas, reports The Eagle. Medical use of cannabis to treat epileptic seizures was an effective approach for Julia as she was able to recover from epileptic seizures with marijuana use.  

ALSO READ: Know Doctors Recommended Marijuana Tips

Julia Efforts For Expanding Medical Use Of Cannabis In Texas

Julia is currently working on expanding the state’s Compassionate Use Program, and for that, she seeks to influence Texas-Legislatures. She has been very active to encourage and convince lawmakers to expand their medical use of cannabis. Moreover, she has devoted herself to the cause and has been doing so since 2019.

She is also a participant in the Texas Compassionate Use Program, which allows physicians and psychiatrists to use low-THC medicines and products. Moreover, doctors under the program rules can give specific small doses for treating various health-related conditions to those patients who qualify.

In 2015 she advocated for passing the Texas Compassionate Use Program to treat more people with cannabis. In 2019 more qualifying conditions became part of the program. At the time, Julia testified before legislators. 

According to Julia Patterson, expanding the program will make a difference and improve the quality of life. Especially those that can recover from certain diseases with sufficient larger doses of marijuana. Her life altered after getting treatment with marijuana in the form of CBD-oil, and she wants to do the same for others.

Julia desires not only to expand the Compassionate Use Program but also increase the limits of THC. So far, individuals can get only 0.5% THC in any cannabis-based formulation as per the program instructions. However, the program allows for low THC % medication because it is psychoactive and capable of producing a high feeling. Moreover, according to Jayne Reuben, chronic use of high THC medications can lead to Cannabis-use disorder. 

Julia Peterson Recovers From Epileptic Seizers By Using CBD-Oil

Peterson had brain surgery and three medical implants. She was on a ketogenic diet for five years and received various medications. However, of the things she does or eats, nothing was effective in treating or controlling the seizures

She was missing a lot of normal-life and suffering due to epileptic seizures. In February 2018, she was given CBD-oil for treatment through the Compassionate Use Program. According to her, within two months, she was entirely seizure-free. She was able to have a healthy life.

ALSO READ: CBD Oil Solutions To Many Pandemic Mental Health Issues

Along with CBD-oil, she was on second-seizure medication, and the treatment made her life better for good. Moreover, her recovery via medical use of cannabis encourages and motivates her to convince lawmakers to expand the Compassionate Use Program. Furthermore, she suggests that some qualification-conditions shall be part of the list that includes allowing the use of marijuana for non-terminal cancer, PTSD, and chronic pain patients. 

According to Julia, if an individual has a chance of recovery from any disease, by using marijuana, then the doctors shall have access to give the doses. 

According to Julia, increasing the THC percentage from 0.5% to between 1% and 5% will be effective and safe. Julia elaborates that monitoring of patients who receive cannabis-medication always occurs. Furthermore, prescribers monitor, supervise, and administer medication to such patients. The prescriber keeps in check alterations in the condition to ensure intoxication does not occur. They work to improve the quality of life of the patient.

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