According to current scientific knowledge, we are presently certain that cannabinoids are significant biochemical mediators in the skin, regardless of whether their mechanisms have not been surely known yet. After years of lab research, the treatment of skin ailments and conditions with cannabinoids is, at last, entering an “informal” clinical stage. With more and more patients utilizing cannabis oils, creams, and balms to treat or control their skin issues.
In the course of recent years, research has started to clarify how cannabinoids can trigger biochemical responses in animal bodies. Such as helping to heal or shield the skin from the symptoms of various dermatological conditions. As an outcome of both lab data and patient experience, CBD is today viewed as a standout amongst the most encouraging compounds for the treatment of a variety of skin ailments.
Now let’s have a look what cannabis can do for skin.
The vast majority have had acne in some form. This condition happens when skin secretions clog up the pores. Chemicals, lotions, and exfoliators are available to manage skin inflammation, alas, frequently without totally tackling the issue. The endocannabinoid system plays a vital role in the regulation of sebum production by modulating the activity of sebaceous organs. And it would appear that CBD is capable of diminishing sebum production.
An ongoing report on acne clearly demonstrates the mitigating properties of CBD. The research features that the anti-acne action is communicated by hindering the strange lipid production under the skin by diminishing cell multiplication and by bringing down the excess cytokines that cause aggravation.
The mitigating activity of THC, CBD, and furthermore cannabinol (CBN) and cannabigerol (CBG) were observed to have the capability to hinder the multiplication of skin cells. In 2007, an investigation noticed that these cannabinoids hindered the development of keratinocytes in the external layers of the skin.
Supporting a potential job for cannabinoids in the treatment of psoriasis. Likewise, the diminished immune reaction from the skin incited by CBD and THC is another impact that adds to the treatment of psoriasis symptoms. In 2016, a survey of accessible scientific literature affirmed that cannabinoids may represent a helpful treatment for this condition. Regardless of whether large scale clinical examinations will be important to affirm both these outcomes and the beneficial outcomes effectively detailed by patients.
Researches against skin tumor
Information about the antitumor impact of endocannabinoids and phytocannabinoids are amassing. Lab research demonstrates these compounds may inhibit tumor cell expansion and improve intra-tumor apoptosis.
Beginning from Rick Simpson’s case, there are a lot of narrative reports on cannabis extracts effectively applied to the skin so as to heal melanoma and different types of tumors. These outcomes were then affirmed in controlled conditions, where cannabinoids were reported to inhibit the development of melanoma cell lines by actuating apoptosis.
Today, researchers really consider cannabinoid receptors as promising targets for the treatment of melanoma. However, while waiting for the exploration to enter a clinical stage. It is sensible to consider cannabinoids just as complementary solutions to conventional surgical or pharmacological treatments.
Scientists Use Computer Intelligence In Cannabis Research
Just twenty years ago, computers couldn’t store more than a hundred characters on screen before running out of memory. We’ve made untold progress in tech since then, and every field stands to benefit. Where once scientists would struggle to plot everything out by hand, computers breeze through the data in seconds. And from time to time, we end up being the ones learning from our own creations.
A study out of the University of Colorado has led to shock from the international community when it poked holes in our knowledge. This happens all the time in science, though – Stephen Hawking spent a large part of his career correcting himself. But this incident stands out because advanced computer software was the one to burst our bubble this time. And boy, did it leave everyone stunned.
Cannabinoids are difficult to study
Let’s back up for a second. We spend a lot of time here advocating for cannabis usage, and that isn’t changing. However, we also advocate for scientific advancement, and that is why these findings are so relevant. To be clear, a lot of what we know about the effects of cannabis is still true. What has changed is the way we understand complex relationships between the myriad of chemicals in cannabis and how they lead to the experience we all love. And we have computer based learning to thank for that.
So let’s get right into it. For starters, ‘cannabis’ or the two widely known species of the plant, contains hundreds of different chemicals inside the leaves. Some of these, the ones that contribute to the high like THC (tetrahydrocannabinol) and CBD (cannabidiol) are well known. But aside from these, there are numerous other chemicals whose effects we aren’t really sure about. And even excluding those, these chemicals can react in such a way to produce even more chemicals after the fact. So it clearly is not easy to simply make a chart of the different chemicals and their effects. That’s why our conventional, experiment based methods won’t work, and why we need computer learning.
How computers are changing the field
Previously, scientists assumed that THC and CBD were different products of the same precursor chemical, Cannabigerolic acid (CBGA). Scientists assumed before was under exposure to heat, certain chemical reactions take place that make CBGA turn into either one of the two, via a series of steps. What implies is that if any one between the two chemicals i.e. THC or CBD was high in concentration, the other had to be lower in order to balance out. That makes sense, because there’s a fixed amount of CBGA to start out with, and that has to be the same amount converted into both THC and CBD.
And that’s where these scientists made their mistake. Using computers, researchers divided different species of Cannabis by what their most common usage was, and compared the composition of each. This is a technique called “Dimensionality Grouping” and it sounds a lot easier than it is. For a proper study like this, you need to find the exact chemical makeup of each type of plant across a few hundred specimens to get rid of natural fluctuations in the compositions. Cutting out the jargon, that is a lot of work, but thankfully we have amazing computers that brute-force these problems for us instead.
So what does that all mean for me, the average cannabis user?
Frankly, it means nothing. But this opens up a large variety of uses in medicine, chemical engineering and other fields once we understand how these molecules interact. The applications come later; first comes the hard work. And without computers, we’d still be in the dark about how our favorite chemicals work.
Major Canadian City Takes First Steps Towards Cannabis Legislation
As the developed world pushes towards more open laws regarding the sale and distribution of cannabis, it’s wonderful to see the tide of public opinion sway the law. It is truly an emboldening sight to see the will of the many override the political agendas of the few. In this case, Ottawa city residents celebrate as recent polls show the majority of citizens are pro-cannabis legalization. Following such developments, the state has decided to investigate the effects of cannabis in the light of science.
This measure is a commendable step towards normalizing recreational drugs and creating a safer and more tolerant society. It’s no secret that cannabis usage is socially disapproved. That doesn’t mean, however, that there is any basis in fact for that negative reputation. Thankfully, Ottawa’s heads of state exist to serve, and aren’t shy of accepting when they’re wrong. Or learning to rethink their viewpoints, either.
Most people agree less regulation, more toleration is the way forward
As seen reflected in recent polls, more than 60 per cent of Ottawa residents are in favor of more broad-minded approaches to the cannabis issue. Riding the wave of acceptance the 2018 federal legalization of cannabis brought throughout Canada, legislators have begun rolling back restrictions. And that is honestly great news. It is a much needed reminder for North America that our democracy is worth fighting for.
Canadian legislators have begun the long work of making cannabis laws more open and tolerant. To this end, Health Canada has decided to take the help of scientists and health experts to inform their decisions. This is a very good approach, because it lessens the influence social factors have upon law forming. And when the science backs up the relative harmlessness of the drug, opinions are sure to change. As the federal healthcare provider, Health Canada has a serious responsibility to be the most well informed about every drug’s potential risks. So it is good to see them taking positive steps to evaluate the risks and outcomes cannabis has, however few they may be.
Canada’s laws on cannabis may need refinement
While it was a shock to the world when cannabis became federally legalized in 2018, it came with some drawbacks too. For one, the shift in public approval was extremely rapid – that meant there wasn’t enough time for proper discourse. People spent most of their time working to make cannabis legal, and not how that legalization should work. As a result, what we have in Canada is a flawed system made with the best of intentions.
Most young users report they have never tried the drug at all, according to the Canadian Center for Drug Use and Addiction. A concerning trend is that those who do try weed for the first time end up getting it from the wrong source: the black market. It is possible that illegal drug dealers might mix in powerful addictive substances just to get people hooked. But with such a large area, and so few retailers, the black market currently has much more reach than legal stores.
The hardest work is done, but there is still a ways to go
The countrywide legalization of cannabis is a powerful message to the world. In the US, we’re still quite far from that happening. The hardest part of the journey is done, but there is still a lot left to do. Canada can’t get away with ‘just average’ drug control: it needs to be the best to pave the way globally. And with steps like the one Ottawa’s government just took, it’s not hard to believe it will.
How Michigan’s New Cannabis Social Equity Reforms Work
Cannabis regulations, when done right, can pave the way for an equal and prosperous society. Unfortunately, much of history, especially in the United States of America, reflects the opposite. The nation’s long standing so-called ‘War On Drugs‘ still leaves lasting scars on entire communities. That’s why when it comes to racial justice and activism, expungement of cannabis-related charges can bring a lot of good. And especially since studies show black and non-white minorities faced tremendously greater risk of arrest then white cannabis users. Enter the Black & Brown Cannabis Guild.
In Michigan, a state where recreational and medicinal marijuana received legal status in 2018, wrongs need righting. Over the past several decades, countless convictions subjected the innocent. And the punishments, disproportionately severe in relation to the offence, certainly didn’t fit the crime. Simple possession of cannabis could lead to misdemeanor charges, while usage often led to jail time. All of these criminal prosecutions led to permanent stains on records, leading to further marginalization for many.
The Black And Brown Cannabis Guild (BBCG) seeks to secure recompense for racial persecutions
Once Michigan legalized cannabis usage, the obvious question arose. What about those currently serving sentences over cannabis charges, and those with permanent strikes? After all, the countless African American, Latino and other people of color being punished should no longer face criminal records. That’s like prosecuting homosexual relationships, years after the practice got decriminalized. It certainly seemed like amnesty and a clean slate were sorely due.
Recently, the state of Vermont signed off on proposed bills that would try to improve social equity. The two main ways the bill seeks to do this included increased funding for small retailers and expungement. The former seeks to help out minority owners of cannabis stores get up on their feet and compete with bigger, more-privileged chains. And the latter measure would not only immediately release convicts but also wipe the slate clean for all with cannabis charges. Only with this, the bill says, will marginalized communities gain the tools to overcome decades of racism and prejudice.
The War On Drugs left many minority communities persecuted, and expungement is the only moral compensation
The United States at some point decided that drugs of any kind needed brutality to get rid of, at any cost. As a result, police raids, widespread arrests, convictions and wiretaps became all too common since the 1970s. The Nixon-era policy sought to curb increasing illegal drug use, despite not targeting the root causes behind drug usage. This means that instead of combatting poverty, addiction, gang influences and corruption the program simply punished the poor users. The BBCG therefore wants to assist the people of color, and anyone else, wrongfully persecuted.
People with cannabis charges on their permanent record simply face too much oppression. Even outside of jail, they bear reduced likelihoods of employment opportunities, security checks, prejudice and stigma. They carry the label the police wrongfully stuck to them. It doesn’t matter if the arrest was over a simple weed joint or crystal methamphetamine, the stigma remains the same. Furthermore, entire minority communities of former convicts often face discrimination.
The move comes as long overdue, but it is still a step in the right direction
Nothing the government does can magically erase decades of oppression. And it also cannot cure racism, bigotry or discrimination overnight. However, by issuing due apologies, absolving the convicted of charges and funding minority communities, something positive is carried out. These steps hopefully will go a long way for many marginalized groups, as the BBCG hopes.
We can only hope other states catch onto this much-needed policy. For the latest, stay tuned!
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